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Results for "

(R,R)-MMP-1-IN-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (3) Apoptosis (9) Cadherin (1) Caspase (1) Drug Isomer (2) Fluorescent Dye (1) Microtubule/Tubulin (3) MMP (83) NF-κB (2) Reactive Oxygen Species (ROS) (1) SDCBP (1) Small Interfering RNA (siRNA) (34) STAT (1)
By Research Areas:	Cancer (40) Cardiovascular Disease (3) Inflammation/Immunology (16) Metabolic Disease (3) Neurological Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (9) Mouse Pre-designed siRNA Sets (10) Human Pre-designed siRNA Sets (15) siRNAs (34)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

GMP Molecules

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-135232

MMP-9-IN-1 Maximum Cited Publications 8 Publications Verification	MMP	Cancer
MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor, which selectively target the hemopexin (PEX) domain of MMP-9, but not other MMPs .

HY-151540

MMP-7-IN-1 1 Publications Verification	MMP	Cancer
MMP-7-IN-1 is a highly potent and selective *MMP-7* inhibitor with an IC₅₀ of 10 nM. MMP-7-IN-1 can be used in the research of diseases such as cancer and fibrosis .

HY-112546

MMP-2 Inhibitor I	MMP	Cancer
MMP-2 Inhibitor I (OA-Hy) is a potent MMP-2 inhibitor with a K_i of 1.7 μM .

HY-124029

BI-4394 MMP13-IN-3	MMP	Inflammation/Immunology
BI-4394 (MMP13-IN-3), a chemical probe, is a potent, selective, and orally active *MMP-13* inhibitor (IC₅₀=1 nM ) for the potential treatment of osteoarthritis . BI-4394 is >1000 selective over other MMPs .

HY-P2179

MMP-1/MMP-9 Substrate, Fluorogenic	Fluorescent Dye MMP	Others
MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9 .Ex/Em = 340/440 nm

HY-146754

MMP2-IN-1 1 Publications Verification	MMP Apoptosis	Cancer
MMP2-IN-1 is a moderate potenet *MMP2* inhibitor with IC₅₀ of 6.8 µM. MMP2-IN-1 exhibits remarkable antiproliferative activity in certain cancer cells by arresting the cell cycle and inducing apoptosis .

HY-116399

MMP-2/MMP-9-IN-1	MMP	Cancer
MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase (MMP-9 and *MMP-2) inhibitor with IC₅₀s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1* is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer .

HY-12093

MMP408 1 Publications Verification	MMP	Inflammation/Immunology
MMP408 is a selective and orally effective inhibitor of *MMP-12* with IC₅₀ values for human, mouse and rat *MMP-12* of 2 nM, 160 nM and 3 μM respectively. MMP408 exhibits IC₅₀ value for human *MMP-13* of 120 nM, and its activity against other MMPs is weak. MMP408 can alleviate inflammation, fibrosis and tissue remodeling by inhibiting MMP-12. MMP408 can be used in the research of chronic obstructive pulmonary disease and chronic sinusitis with nasal polyps .

HY-128133

MMP-8 inhibitor-1 MMP8-I	MMP	Cancer
MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent *MMP-8* inhibitor without significant oral bioavailability .

HY-114418

MMP3 inhibitor 1 1 Publications Verification	MMP	Cancer
MMP3 inhibitor 1 is a potent and highly selective *MMP-3* inhibitor with an IC₅₀ of 1 nM .

HY-119423

MMP Inhibitor II	MMP	Cancer
MMP Inhibitor II (compound 4e) is a potent, reversible pan-MMP inhibitor with IC₅₀ values of 24 nM, 18.4 nM, 30 nM, and 2.7 nM for MMP-1,MMP-3, MMP-7, and MMP-9, respectively .

HY-153563

MMP-7-IN-2	MMP	Cancer
MMP-7-IN-2 is a potent and selective inhibitor of *MMP7* with an IC₅₀ value of 16 nM. MMP-7-IN-2 can be used for the research of diseases such as cancer and fibrosis .

HY-156430

MMP-7-IN-3	MMP	Cancer
MMP-7-IN-3 is a potent and selective inhibitor of *MMP-7. MMP*-7-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction .

HY-128026

MMP-9/MMP-13 Inhibitor I	MMP	Inflammation/Immunology
MMP-9/MMP-13 Inhibitor I is a potent *MMP-9* and *MMP-13* inhibitor with IC₅₀s of both 0.9 nM. MMP-9/MMP-13 Inhibitor I shows >20-folds selectivity for MMP-9/MMP-13 over other MMPs .

HY-122624

MMP13-IN-2	MMP	Inflammation/Immunology
MMP13-IN-2 is a potent, selective and orally active *MMP-13* inhibitor. MMP13-IN-2 exhibits excellent potency for MMP-13 (IC₅₀=0.036 nM) and selectivities (greater than 1,500-fold) over MMP-1, 3, 7, 8, 9, 14, and TACE. MMP13-IN-2 has the ability to block the release of collagen from cartilage in vitro. MMP13-IN-2 has the potential for collagenase related disease research .

HY-152092

MMP-1-IN-1 1 Publications Verification	MMP	Cancer
MMP-1-IN-1 (Compound 6) is a highly potent *MMP-1* inhibitor with an IC₅₀ of 0.034 μM .

HY-12093A

*(R)-MMP408*	Drug Isomer MMP Cadherin	Inflammation/Immunology
(R)-MMP408 is an isomer of MMP408 (HY-12093). MMP408 is an orally active *MMP-12* inhibitor (IC₅₀=2.0 nM for hMMP-12) that effectively interferes with the epithelial-mesenchymal transition (EMT) process. MMP408 significantly upregulates the expression of E-cadherin in nasal epithelial cells, while inhibiting mesenchymal markers such as vimentin, α-smooth muscle actin and fibronectin, thereby reversing the EMT phenotype. MMP408 is used in studies of airway remodeling-related diseases, including chronic rhinosinusitis with nasal polyps, chronic obstructive pulmonary disease (COPD) and asthma .

HY-147745

MMP2-IN-2	MMP	Cancer
MMP2-IN-2 (compound 42) is a potent and selective *MMP-2* (matrix metalloproteinases) inhibitor, with an IC₅₀ of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against *MMP-13, MMP-9* and *MMP-8, with IC₅₀* values of 12, 23.3, and 25 μM, respectively .

HY-116302

MMP-9-IN-9	MMP	Neurological Disease Inflammation/Immunology
MMP-9-IN-9 (compound 4f) is a slective *MMP-9* inhibitor with an IC₅₀ of 5 nM. MMP-9-IN-9 shows selective for MMP-9 over MMP-1 and MMP-13. MMP-9-IN-9 shows strong anti-inflammatory and neuroprotective effects .

HY-161285

MMP-9/10-IN-2	MMP	Cancer
MMP-9/10-IN-2 (compound 6e) is a potent inhibitor of *MMP10 and MMP9, with IC₅₀* of 0.076 μM for *MMP*10, and 93.18% inhibition at 0.5 μM for *MMP9. MMP*-9/10-IN-2 plays an important role in anti-tumor .

HY-P10143

MMP-2/MMP-9 Substrate Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt	MMP	Others
MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .

HY-P10043

MMP-1 Substrate	MMP	Others
MMP-1 Substrate is a matrix metalloproteinase-1 (MMP-1) selective substrate that can be used for the fluorometric determination of MMP-1 enzymatic activity .

HY-130391

MMP12-IN-3	MMP	Inflammation/Immunology
MMP12-IN-3 (compound 32) is a potent *MMP12* inhibitor with an IC₅₀ value of 4.9 nM. MMP12-IN-3 has the potential for the research of chronic respiratory diseases such as emphysema .

HY-RS08528

MMP14 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA) MMP	Others
MMP14 Human Pre-designed siRNA Set A contains three designed siRNAs for MMP14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MMP14 Human Pre-designed siRNA Set A MMP14 Human Pre-designed siRNA Set A

HY-P11348

*TG-MMP-Lys*	MMP	Cancer
TG-MMP-Lys is an *MMP*-sensitive crosslinking peptide. TG-MMP-Lys is promising for research of fibrotic diseases (e.g., liver fibrosis) .

HY-P2414

MMP-13 Substrate	MMP	Inflammation/Immunology
MMP-13 Substrate is a substrate of MMP-13. MMP-13 Substrate can be used for the research of osteoarthritis (OA) .

HY-130076

MMP-2 Inhibitor II	MMP	Cancer
MMP-2 Inhibitor II (compound 2) is a selective *MMP-2* inhibitor. The Kinetic parameters for MMP inhibition are 2.4 μM (MMP-2), 45 μM (MMP-1), and 379 μM (MMP-7), respectively .

HY-149848

MMP-9-IN-6	MMP	Inflammation/Immunology
MMP-9-IN-6 (Compound 3g) is a *MMP-9* inhibitor with IC₅₀ value of 50 μM, which has good anti-ulcer effect .

HY-RS22645

Mmp16 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mmp16 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mmp16 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mmp16 Mouse Pre-designed siRNA Set A Mmp16 Mouse Pre-designed siRNA Set A

HY-RS08558

Mmp9 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA) MMP	Others
Mmp9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mmp9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mmp9 Mouse Pre-designed siRNA Set A Mmp9 Mouse Pre-designed siRNA Set A

HY-RS08557

MMP9 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA) MMP	Others
MMP9 Human Pre-designed siRNA Set A contains three designed siRNAs for MMP9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MMP9 Human Pre-designed siRNA Set A MMP9 Human Pre-designed siRNA Set A

HY-P2166

MMP3 inhibitor 3	MMP	Cancer
MMP3 inhibitor 3 is an inhibitor of *MMP3. MMP*3 inhibitor 3 can used to study breast cancer .

HY-175558

MMP-9-IN-12	MMP Apoptosis Reactive Oxygen Species (ROS)	Cancer
MMP-9-IN-12 is a matrix metalloproteinase-9 (MMP-9) inhibitor with an IC₅₀ of 6.57 μM. MMP-9-IN-12 shows an IC₅₀ value of 1.54 μM for HCT-116 cells. MMP-9-IN-12 induces cell apoptosis, ROS production and mitochondrial depolarization. MMP-9-IN-12 inhibits cells migration and disrupts cell cycle progression. MMP-9-IN-12 can be used for the research of colorectal cancer (CRC) .

HY-152030

*Tubulin/MMP-IN-2*	Microtubule/Tubulin MMP Apoptosis	Cancer
Tubulin/MMP-IN-2 is dual inhibitor of tubulin and matrix metalloproteinases. Tubulin/MMP-IN-2 can strongly inhibit tubulin polymerization and induces cell apoptosis. Tubulin/MMP-IN-2 has inhibitory activities against MMP-2, MMP-3 and MMP-9 with IC₅₀ values of 24.95 μM, 31.60 μM and 22.37 μM, respectively. Tubulin/MMP-IN-2 can be used for the research of cancer .

HY-110397G

KP-457	MMP	Cardiovascular Disease
KP-457 (GMP) is KP-457 (HY-110397) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture.KP-457 is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, with higher selectivity for ADAM17 than for other MMPs and ADAM10, and IC₅₀s are 11.1 nM (ADAM17), 748 nM (ADAM10), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively .

HY-156247

IVMT-Rx-3	SDCBP NF-κB MMP	Cancer
IVMT-Rx-3 is a inhibitor of SDCBP targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin. IVMT-Rx-3 blocks MDA-9/Syntenin interaction with Src, reduces NF-κB activation, and inhibits *MMP-2/MMP-9* expression. IVMT-Rx-3 inhibits Melanoma Metastasis ^[1]

HY-176412

MMP-9-IN-11	MMP	Cancer
MMP-9-IN-11 (compound 77) is a potent *MMP-9* inhibitor. MMP-9-IN-11 exhibits significant cytotoxic activity against A549 and L929 with IC₅₀s of 4.04 and 13.97 μg/mL, respectively .

HY-161284

MMP-9/10-IN-1	MMP	Cancer
MMP-9/10-IN-1 (Compound 6b) is a potent dual *MMP-9/10* Inhibotor with IC₅₀s of 0.076 and 0.139 μM against NSCLC and A549 cells, respectively. MMP-9/10-IN-1 has anti-invasive and anti-angiogenic activities when in combination with Sorafenib (HY-10201) .

HY-P2166A

MMP3 inhibitor 3 TFA	MMP	Cancer
MMP3 inhibitor 3 (TFA) is an inhibitor of *MMP3. MMP*3 inhibitor 3 (TFA) can used to study breast cancer .

HY-146006

*Tubulin/MMP-IN-1*	Microtubule/Tubulin MMP	Cancer
Tubulin/MMP-IN-1 (compound 15g) is a potent inhibitor of tubulin and *MMP. Tubulin/MMP-IN-1 has the potential for the research of cancer diseases. Tubulin/MMP*-IN-1 suppresses tubulin polymerization, induces cell cycle arrest at the G2/M phase, leads to reactive oxidative stress (ROS) generation of HepG2 cells, and results in apoptosis by the mitochondrial-dependent apoptotic pathway .

HY-P2682

MMP-8/MMP-26 Fluorogenic substrate	MMP	Metabolic Disease
MMP-8/MMP-26 Fluorogenic substrate (DNP-Pro-Leu-Ala-Tyr-Trp-Ala-Arg) is a matrix metalloproteinase-8 (MMP-8) fluorogenic substrate. MMP-8/MMP-26 Fluorogenic substrate can be used for the research of atherosclerosis, pulmonary fibrosis, and sepsis .

HY-14155

MMP145	MMP	Inflammation/Immunology
MMP145 (compound 27) is a potent, selective and orally active *MMP-12* inhibitor. MMP145 is effective in inflammation and asthma reasearch .

HY-146218

MMP-9-IN-5	MMP Akt Apoptosis	Cancer
MMP-9-IN-5 is a *MMP-9* inhibitor (IC₅₀: 4.49 nM) that forms hydrogen bond with MMP-9. MMP-9-IN-5 also inhibits _AKT activity (IC₅₀: 1.34 nM). MMP-9-IN-5 shows cell cytotoxicity and induces cell apoptosis. MMP-9-IN-5 can be used in the research of cancers .

HY-146216

MMP-9-IN-3	MMP Akt Apoptosis	Cancer
MMP-9-IN-3 is a *MMP-9* inhibitor (IC₅₀: 5.56 nM) that forms hydrogen bond with MMP-9. MMP-9-IN-3 also inhibits AKT activity (IC₅₀: 2.11 nM). MMP-9-IN-3 shows cell cytotoxicity and induces cell apoptosis. MMP-9-IN-3 can be used in the research of cancers .

HY-147746

MMP2-IN-3	MMP	Cancer
MMP2-IN-3 (compound 2) is a potent *MMP-2* (matrix metalloproteinases) inhibitor, with an IC₅₀ of 31 μM. MMP2-IN-3 also shows inhibitory activity against *MMP-9* and *MMP-8, with IC₅₀* values of 26.6, and 32 μM, respectively .

HY-146217

MMP-9-IN-4	MMP Akt Apoptosis	Cancer
MMP-9-IN-4 is a *MMP-9* inhibitor (IC₅₀: 7.46 nM) that has H-π interactions with MMP-9. MMP-9-IN-4 also inhibits _AKT activity (IC₅₀: 8.82 nM). MMP-9-IN-4 shows cell cytotoxicity and induces cell apoptosis. MMP-9-IN-4 can be used in the research of cancers .

HY-153913

MMP-9-IN-7	MMP	Inflammation/Immunology
MMP-9-IN-7 is a potent *MMP9* inhibitor with an IC₅₀ of 0.52 μM in proMMP9/MMP3 P126 activation assay. MMP-9-IN-7 is extracted from patent WO2012162468 (example 59), and can be used for MMP9/MMP13 mediated syndrome research .

HY-P2414A

MMP-13 Substrate TFA	MMP	Inflammation/Immunology
MMP-13 Substrate TFA is a substrate of MMP-13. MMP-13 Substrate TFA can be used for the research of osteoarthritis (OA) .

HY-161707

MMP2-IN-4	MMP	Cancer
MMP2-IN-4 (compound 3h) is a potent *MMP2* inhibitor. MMP2-IN-4 inhibits *MMP2, MMP9* and *MMP12* with IC₅₀s of 266.74, 402.75 and 1237.39 nM, respectively .

HY-170604

MMP-2 Inhibitor-4	MMP	Cardiovascular Disease Cancer
MMP-2 Inhibitor-4 (Compound 5g) is an *MMP-2* inhibitor with an IC₅₀ of 152.62 nM. MMP-2 Inhibitor-4 can reduce the levels of *MMP-2* in the K562 cell line through stable binding at the MMP-2 active site, and it demonstrates strong antiangiogenic effects in the ACHN cell line. MMP-2 Inhibitor-4 holds promise for research in chronic myeloid leukemia (CML) .

Cat. No.	상품명

HY-L185

Anti-Fibrosis Compound Library

2,415 compounds

Fibrosis is a kind of repair response to long-term tissue damage, which is mainly manifested by excessive deposition of extracellular matrix (ECM) and scar formation. Myofibroblasts are the main generating cells of extracellular matrix, and their activation process is related to various pathological mechanisms including Oxidative stress, chronic inflammation and cytokine secretion. Fibrosis can occur in many organs, such as kidneys, liver, heart, lungs, etc. Continuous fibrosis can lead to the destruction of the normal structure of tissues and organs, and if not controlled in time, may cause organ failure or even life-threatening.

MCE contains 2,415 compounds targeting ant-fibrosis targets such as TGF-β, PI3K, Wnt, MMP, etc. These compounds have clear or potential anti-fibrosis activity and can be used for mechanism research and drug screening of fibrosis diseases.

HY-L012

Metabolism/Protease Compound Library

7,056 compounds

Metabolism is the set of life-sustaining chemical reactions in organisms. Metabolic pathways are enzyme-mediated biochemical reactions that lead to biosynthesis (anabolism) or breakdown (catabolism) of natural product small molecules within a cell or tissue. Acting as catalysts, enzymes are crucial to metabolism - they allow a reaction to proceed more rapidly - and they also allow the regulation of the rate of a metabolic reaction. Proteases are used throughout an organism for various metabolic processes. Proteases control a great variety of physiological processes that are critical for life, including the immune response, cell cycle, cell death, wound healing, food digestion, and protein and organelle recycling. Imbalances in metabolic activities have been found to be critical in a number of pathologies, such as cardiovascular diseases, inflammation, cancer, and neurodegenerative diseases.

MCE designs a unique collection of 7,056 Metabolism/Protease-related small molecules that act as a useful tool for drug discovery of metabolism-related diseases.

HY-L210

Anti-Rheumatic Arthritis Compound Library

1,883 compounds

Rheumatoid Arthritis (RA) is a autoimmune disease characterized by persistent joint inflammation. The pathology of RA includes immune cell infiltration, synovial lining proliferation, pannus formation, and the destruction of joint cartilage and bone, which is highly disabling. Due to long-term chronic inflammation, RA not only severely affects the quality of life of patients but can also damage multiple organs, leading to lung diseases, cardiovascular diseases, and malignant tumors. The pathogenesis of RA is complex, involving genetic, environmental, and immune factors. With the advancement of high-throughput screening technology, screening for compounds targeting JAK, CCR, MEK, MMP targets may contribute to the development of more effective drugs against Rheumatoid Arthritis (RA).

MCE has collected 1,883 small molecule compounds with definite or potential anti-rheumatoid arthritis activity. This library is of significant value for researching the anti-RA drugs.

Cat. No.	상품명	Type

HY-110397G

KP-457

Fluorescent Dyes

KP-457 (GMP) is KP-457 (HY-110397) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture.KP-457 is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, with higher selectivity for ADAM17 than for other MMPs and ADAM10, and IC₅₀s are 11.1 nM (ADAM17), 748 nM (ADAM10), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively .

Cat. No.	상품명	Type

HY-110397G

KP-457

Biochemical Assay Reagents

Cat. No.	상품명	Target	Research Area

HY-P2179

MMP-1/MMP-9 Substrate, Fluorogenic	Fluorescent Dye MMP	Others
MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9 .Ex/Em = 340/440 nm

HY-153563

MMP-7-IN-2	MMP	Cancer
MMP-7-IN-2 is a potent and selective inhibitor of *MMP7* with an IC₅₀ value of 16 nM. MMP-7-IN-2 can be used for the research of diseases such as cancer and fibrosis .

HY-156430

MMP-7-IN-3	MMP	Cancer
MMP-7-IN-3 is a potent and selective inhibitor of *MMP-7. MMP*-7-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction .

HY-P10143

MMP-2/MMP-9 Substrate Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt	MMP	Others
MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .

HY-P10043

MMP-1 Substrate	MMP	Others
MMP-1 Substrate is a matrix metalloproteinase-1 (MMP-1) selective substrate that can be used for the fluorometric determination of MMP-1 enzymatic activity .

HY-P11348

*TG-MMP-Lys*	MMP	Cancer
TG-MMP-Lys is an *MMP*-sensitive crosslinking peptide. TG-MMP-Lys is promising for research of fibrotic diseases (e.g., liver fibrosis) .

HY-P2414

MMP-13 Substrate	MMP	Inflammation/Immunology
MMP-13 Substrate is a substrate of MMP-13. MMP-13 Substrate can be used for the research of osteoarthritis (OA) .

HY-P2689

DNP-PLGMWSR	Peptides	Others
DNP-PLGMWSR is a? fluorogenic substrate for *MMP-2 and MMP*-9 .

HY-P2166

MMP3 inhibitor 3	MMP	Cancer
MMP3 inhibitor 3 is an inhibitor of *MMP3. MMP*3 inhibitor 3 can used to study breast cancer .

HY-P2166A

MMP3 inhibitor 3 TFA	MMP	Cancer
MMP3 inhibitor 3 (TFA) is an inhibitor of *MMP3. MMP*3 inhibitor 3 (TFA) can used to study breast cancer .

HY-P2682

MMP-8/MMP-26 Fluorogenic substrate	MMP	Metabolic Disease
MMP-8/MMP-26 Fluorogenic substrate (DNP-Pro-Leu-Ala-Tyr-Trp-Ala-Arg) is a matrix metalloproteinase-8 (MMP-8) fluorogenic substrate. MMP-8/MMP-26 Fluorogenic substrate can be used for the research of atherosclerosis, pulmonary fibrosis, and sepsis .

HY-P2414A

MMP-13 Substrate TFA	MMP	Inflammation/Immunology
MMP-13 Substrate TFA is a substrate of MMP-13. MMP-13 Substrate TFA can be used for the research of osteoarthritis (OA) .

HY-P4905

Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2	MMP	Cancer
Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is highly selective substrate for matrix metalloproteases 12 (MMP12) substrate with a kcat/Km value of 1.8510 ⁵ M ^-1s ^-1, and poor substrate of other MMPs with the exception of MMP13* (kcat/Km = 0.5310 ⁵ M ^-1s ^-1) and MMP9* (0.33*10 ⁵ M ^-1s ^-1) .

Cat. No.	상품명	Target	Research Area	Image

HY-P990468

*Anti-MMP9 Antibody*	MMP	Inflammation/Immunology
Anti-MMP9 Antibody is a CHO-expressed human antibody that targets *MMP9. The Anti-MMP9 Antibody is composed of a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.76 kDa. For the isotype control of the Anti-MMP*9 Antibody, you can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P992267

*Anti-MMP-16 Antibody*	MMP	Inflammation/Immunology
Anti-MMP-16 Antibody is a monoclonal antibody targeting MMP-16. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-MMP-16 Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).

Species:	Human (29) Rat (2) Mouse (11) Cynomolgus (3)
Tag:	His (31) Tag Free (13) Avi (2) Fc (1)
Source:	HEK293 (29) CHO (2) P. pastoris (3) E. coli (11)

Cat. No.	Compare	상품명	Species	Source	Image

HY-P75929A

	MMP-19 Protein, Human Matrix metalloproteinase-19; MMP-19; MMP-18; RASI	Human	E. coli
	MMP-19 proteins act as endopeptidases that degrade multiple components of the extracellular matrix, including aggrecan and cartilage oligomeric matrix protein (comp), during critical developmental processes, hemostasis, and pathological conditions such as arthritis. ) plays a key role. In addition to participating in matrix remodeling, MMP-19 may also contribute to neovascularization, or angiogenesis. MMP-19 Protein, Human is the recombinant human-derived MMP-19 protein, expressed by E. coli , with tag free.

HY-P75929

	MMP-19 Protein, Human (solution) Matrix metalloproteinase-19; MMP-19; MMP-18; RASI	Human	E. coli
	MMP-19 proteins act as endopeptidases that degrade multiple components of the extracellular matrix, including aggrecan and cartilage oligomeric matrix protein (comp), during critical developmental processes, hemostasis, and pathological conditions such as arthritis. ) plays a key role. In addition to participating in matrix remodeling, MMP-19 may also contribute to neovascularization, or angiogenesis. MMP-19 Protein, Human (solution) is the recombinant human-derived MMP-19 protein, expressed by E. coli , with tag free.

HY-P705546

	MMP-14 Protein, Human (C-His) Matrix metalloproteinase 14 ; Matrix metalloproteinase-14; Membrane type 1 matrix metalloproteinase ; Membrane type 1 metalloprotease; Membrane type matrix metalloproteinase 1; Membrane-type-1 matrix metalloproteinase; MMP 14; MMP X1; MMP-14; MMP-X1; MMP14; MMP14_HUMAN; MMPX1; MT MMP 1	Human	E. coli
	MMP-14 protein is an endopeptidase that degrades collagen and activates progelatinase A.

HY-P79097

	MMP-16 Protein, Human (I152N, His) Matrix metalloproteinase-16; MMP16; MMP-16; MMP-X2; Membrane-type matrix metalloproteinase 3; MT-MMP 3; MTMMP3; Membrane-type-3 matrix metalloproteinase; MT3-MMP; MT3MMP; C8orf57; MMPX2; Matrix Metalloproteinase 16/Membrane Type 3 MMP	Human	E. coli
	The MMP-16 protein functions as an endopeptidase capable of degrading various components of the extracellular matrix, particularly type III collagen and fibronectin. Its effects extend to the activation of progelatinase A, which contributes to the dynamic remodeling of the extracellular matrix within blood vessels. MMP-16 Protein, Human (I152N, His) is the recombinant human-derived MMP-16 protein, expressed by E. coli , with C-10*His labeled tag.

HY-P701987

	MMP-13 Protein, Human (His) MMP13; Collagenase 3; Matrix metalloproteinase-13; MMP-13	Human	E. coli
	The MMP-13 protein plays a role in the degradation of extracellular matrix proteins, especially fibrillar collagen, fibronectin, TNC, and ACAN. It cleaves triple-helical collagen, preferentially cleaves type II collagen, and can also target other collagen types. MMP-13 Protein, Human (His) is the recombinant human-derived MMP-13 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70342

	MMP-12 Protein, Mouse (HEK293, His) 1 Publications Verification rMuMacrophage metalloelastase/MMP12, His; Macrophage metalloelastase; MME; Matrix metalloproteinase-12; MMP-12; MMP12; Mme; Mmel	Mouse	HEK293
	MMP-12 protein has significant elastolytic activity and may contribute to tissue damage and remodeling.Its substrate preferences include preference for leucine at the P1' site and aromatic/hydrophobic residues at the P1 site, and preference for small hydrophobic residues such as alanine at the P3 site.MMP-12 Protein, Mouse (HEK293, His) is the recombinant mouse-derived MMP-12 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70250

	MMP-1 Protein, Human (HEK293, His, solution) 1 Publications Verification rHuInterstitial collagenase/MMP-1, His; Interstitial Collagenase; Fibroblast Collagenase; Matrix Metalloproteinase-1; MMP-1; MMP1; CLG	Human	HEK293
	The MMP-1 protein acts as an enzyme capable of cleaving types I, II, and III collagen at specific sites within the helical domain. In addition, it exhibits lytic activity against type VII and type X collagen. MMP-1 Protein, Human (HEK293, His, solution) is the recombinant human-derived MMP-1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70250A

	MMP-1 Protein, Human (HEK293, C-His) rHuInterstitial collagenase/MMP-1, His; Interstitial Collagenase; Fibroblast Collagenase; Matrix Metalloproteinase-1; MMP-1; MMP1; CLG	Human	HEK293
	The MMP-1 protein acts as an enzyme capable of cleaving types I, II, and III collagen at specific sites within the helical domain. In addition, it exhibits lytic activity against type VII and type X collagen. MMP-1 Protein, Human (HEK293, C-His) is the recombinant human-derived MMP-1, expressed by HEK293, with C-6*His labeled tag.

HY-P74744

	MMP-12 Protein, Human Macrophage metalloelastase; MME; MMP-12; HME	Human	E. coli
	MMP-12 protein is potentially engaged in tissue injury and remodeling, displaying significant elastolytic activity. It shows flexibility at the P1' site, accommodating both large and small amino acids, yet favoring leucine. At the P1 site, it prefers aromatic or hydrophobic residues, with a tendency for small hydrophobic residues like alanine in the P3 position. MMP-12 Protein, Human is the recombinant human-derived MMP-12 protein, expressed by E. coli , with tag free.

HY-P705514

	MMP-12 Protein, Human (His) EC 3.4.24.65; HME; Macrophage elastase; Macrophage metalloelastase; Macrophage metaloelastase; Matrix metallopeptidase 12 (macrophage elastase); Matrix metalloprotease 12; Matrix metalloproteinase-12; ME; MGC138506; MME; MMP 12; MMP-12; MMP12; MMP12_HUMAN	Human	E. coli

HY-P70139

	*Stromelysin-1/MMP-3 Protein, Human (HEK293, His)* rHuStromelysin-1/MMP-3, His; Stromelysin-1; SL-1; Matrix metalloproteinase-3; MMP-3; Transin-1; MMP3; STMY1	Human	HEK293
	The Stromelysin-1/MMP-3 protein is a multifunctional metalloprotease that degrades a variety of extracellular matrix components and activates molecules such as growth factors, plasminogen, and MMP9. It is released into the ECM and is activated through the plasmin cascade. Stromelysin-1/MMP-3 Protein, Human (HEK293, His) is the recombinant human-derived Stromelysin-1/MMP-3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76498

	MMP-26 Protein, Human Matrix metalloproteinase-26; MMP-26; Endometase; Matrilysin-2	Human	E. coli
	The MMP-26 protein has broad substrate specificity and hydrolyzes type IV collagen, fibronectin, fibrinogen, β-casein, type I gelatin, and α-1 protease inhibitors. The versatility of this enzyme suggests involvement in the degradation and remodeling of various extracellular matrix components. MMP-26 Protein, Human is the recombinant human-derived MMP-26 protein, expressed by E. coli , with tag free.

HY-P72507

	MMP-8 Protein, Human (HEK293, His) 1 Publications Verification Neutrophil collagenase; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CL; MMP8; CLG1	Human	HEK293
	MMP-8, also known as matrix metalloproteinase-8 or collagenase-2, is recognized for its enzymatic abilities, particularly its ability to break down fibrillar types I, II, and III collagen. This enzymatic activity suggests that MMP-8 plays an important role in the remodeling and turnover of collagen-rich tissues such as connective tissue, cartilage, and bone. MMP-8 Protein, Human (HEK293, His) is the recombinant human-derived MMP-8 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P78328

	MMP-8 Protein, Mouse (HEK293, His) MMP-8; PMNL-CL; CLG1; MMP8; Collagenase 2; PMNL-CL; HNC	Mouse	HEK293
	MMP-8 protein degrades different fibrillar collagens, such as type I, II, and III.It is implicated in the breakdown of collagen fibers during uterine involution.MMP-8 Protein, Mouse (HEK293, His) is the recombinant mouse-derived MMP-8 protein, expressed by HEK293 , with C-His labeled tag.

HY-P73298

	MMP-8 Protein, Human (HEK293) Neutrophil collagenase; MMP-8; PMNL-CL; CLG1	Human	HEK293
	MMP-8, also known as matrix metalloproteinase-8 or collagenase-2, is recognized for its enzymatic abilities, particularly its ability to break down fibrillar types I, II, and III collagen. This enzymatic activity suggests that MMP-8 plays an important role in the remodeling and turnover of collagen-rich tissues such as connective tissue, cartilage, and bone. MMP-8 Protein, Human (HEK293) is the recombinant human-derived MMP-8 protein, expressed by HEK293 , with N-Met labeled tag.

HY-P73808

	MMP-8 Protein, Mouse (HEK293) Neutrophil collagenase; MMP-8; PMNL-CL; CLG1	Mouse	HEK293
	MMP-8 protein degrades different fibrillar collagens, such as type I, II, and III.It is implicated in the breakdown of collagen fibers during uterine involution.MMP-8 Protein, Mouse (HEK293) is the recombinant mouse-derived MMP-8 protein, expressed by HEK293 , with tag free.

HY-P73809

	MMP-8 Protein, Mouse (CHO, His) Neutrophil collagenase; MMP-8; PMNL-CL; CLG1	Mouse	CHO
	MMP-8 protein degrades different fibrillar collagens, such as type I, II, and III.It is implicated in the breakdown of collagen fibers during uterine involution.MMP-8 Protein, Mouse (CHO, His) is the recombinant mouse-derived MMP-8 protein, expressed by CHO , with C-His labeled tag.

HY-P73297

	*Stromelysin-1/MMP-3 Protein, Human* Stromelysin-1; SL-1; MMP-3; Transin-1; STMY1	Human	E. coli
	The Stromelysin-1/MMP-3 protein is a multifunctional metalloprotease that degrades a variety of extracellular matrix components and activates molecules such as growth factors, plasminogen, and MMP9. It is released into the ECM and is activated through the plasmin cascade. Stromelysin-1/MMP-3 Protein, Human is the recombinant human-derived Stromelysin-1/MMP-3 protein, expressed by E. coli , with tag free.

HY-P70268

	MMP-2 Protein, Human (HEK293, His) 3 Publications Verification rHu72 kDa type IV collagenase/MMP-2, His ; 72 kDa Type IV Collagenase; 72 kDa Gelatinase; Gelatinase A; Matrix Metalloproteinase-2; MMP-2; TBE-1; MMP2; CLG4A	Human	HEK293
	MMP-2 protein is a multifunctional metalloproteinase that actively participates in physiological processes such as vascular remodeling, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. In addition to degrading extracellular matrix proteins, it also acts on non-matrix proteins to promote vasoconstriction. MMP-2 Protein, Human (HEK293, His) is the recombinant human-derived MMP-2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P700573

	MMP-2 Protein, Rat (P. pastoris, His) 1 Publications Verification rHu72 kDa type IV collagenase/MMP-2, His ; 72 kDa Type IV Collagenase; 72 kDa Gelatinase; Gelatinase A; Matrix Metalloproteinase-2; MMP-2; TBE-1; MMP2; CLG4A	Rat	P. pastoris
	MMP-2 is a multifunctional metalloproteinase that plays multiple roles in vasculature remodeling, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. In addition to degrading extracellular matrix proteins, MMP-2 also acts on non-matrix proteins to promote vasoconstriction. MMP-2 Protein, Rat (P. pastoris, His) is the recombinant rat-derived MMP-2 protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P700139AF

	*Animal-Free MMP-2 Protein, Human (His)* rHu72 kDa type IV collagenase/MMP-2, His ; 72 kDa Type IV Collagenase; 72 kDa Gelatinase; Gelatinase A; Matrix Metalloproteinase-2; MMP-2; TBE-1; MMP2; CLG4A	Human	E. coli
	MMP-2 protein is a multifunctional metalloproteinase that actively participates in physiological processes such as vascular remodeling, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. In addition to degrading extracellular matrix proteins, it also acts on non-matrix proteins to promote vasoconstriction. Animal-Free MMP-2 Protein, Human (His) is the recombinant human-derived animal-FreeMMP-2 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P700572

	MMP-9 Protein, Human (P. pastoris, His) rHuMatrix metalloproteinase-9/MMP-9, His; Matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; MMP9	Human	P. pastoris
	MMP-9 Protein, a matrix metalloproteinase, plays a crucial role in localized extracellular matrix breakdown, facilitating leukocyte migration. Its potential involvement in bone osteoclastic resorption is suggested. MMP-9 cleaves KiSS1 and NINJ1, generating their secreted forms. It degrades type IV and type V collagen, producing distinct fragments, and fibronectin, while laminin and Pz-peptide remain unaffected. MMP-9 Protein, Human (P. pastoris, His) is the recombinant human-derived MMP-9 protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P73807

	MMP-9 Protein, Mouse (HEK293) 3 Publications Verification Matrix metalloproteinase-9; MMP-9; Gelatinase B; GELB; CLG4B	Mouse	HEK293
	The MMP-9 protein is a matrix metalloproteinase that is critical for local extracellular matrix proteolysis and leukocyte migration.It is suggested that it may be involved in bone osteoclastic resorption.MMP-9 Protein, Mouse (HEK293) is the recombinant mouse-derived MMP-9 protein, expressed by HEK293 , with tag free.

HY-P73300

	MMP-9 Protein, Human (HEK293) 2 Publications Verification Matrix metalloproteinase-9; MMP-9; Gelatinase B; GELB; CLG4B	Human	HEK293
	MMP-9 is an important member of the MMP protein family and regulates the extracellular matrix during physiological processes such as development and tissue remodeling. It involves arthritis and metastasis. MMP-9 Protein, Human (HEK293) is the recombinant human-derived MMP-9 protein, expressed by HEK293 , with tag free.

HY-P700893

	MMP-9 Protein, Cynomolgus (HEK293, His) MMP-9; GELB; CLG4B; MANDP2; Gelatinase B	Cynomolgus	HEK293
	The MMP-9 protein is a matrix metalloproteinase that is critical for local extracellular matrix proteolysis and leukocyte migration. It is suggested that it may be involved in bone osteoclastic resorption. MMP-9 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived MMP-9 protein, expressed by HEK293 , with C-His labeled tag.

HY-P70145A

	MMP-9 Protein, Human (HEK293, C-His) rHuMatrix metalloproteinase-9/MMP-9, His; Matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; MMP9	Human	HEK293
	MMP-9 Protein, a matrix metalloproteinase, plays a crucial role in localized extracellular matrix breakdown, facilitating leukocyte migration. Its potential involvement in bone osteoclastic resorption is suggested. MMP-9 cleaves KiSS1 and NINJ1, generating their secreted forms. It degrades type IV and type V collagen, producing distinct fragments, and fibronectin, while laminin and Pz-peptide remain unaffected. MMP-9 Protein, Human (HEK293, C-His) is the recombinant human-derived MMP-9 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73301

	MMP-9 Protein, Rat (HEK293, His) Matrix metalloproteinase-9; MMP-9; Gelatinase B; GELB; CLG4B	Rat	HEK293
	Matrix metalloproteinase-9 (Mmp9) is a member of the matrix metalloproteinase (MMP) family. Mmp9 is secreted as inactive proproteins which are activated when cleaved by extracellular proteinases to generate a mature, zinc-dependent endopeptidase enzyme that degrades collagens of type IV, V and XI, and elastin. Mmp9 is also involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow. MMP-9 Protein, Rat (HEK293, His) is the recombinant rat-derived MMP-9 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P78492

	MMP-9 Protein, Human (HEK293, His-Avi) MMP-9; GELB; CLG4B; MANDP2; Gelatinase B	Human	HEK293
	MMP-9 Protein, a matrix metalloproteinase, plays a crucial role in localized extracellular matrix breakdown, facilitating leukocyte migration. Its potential involvement in bone osteoclastic resorption is suggested. MMP-9 cleaves KiSS1 and NINJ1, generating their secreted forms. It degrades type IV and type V collagen, producing distinct fragments, and fibronectin, while laminin and Pz-peptide remain unaffected. MMP-9 Protein, Human (HEK293, His-Avi) is the recombinant human-derived MMP-9 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P704792

	MMP-8 Protein, Mouse (242a.a, HEK293, His) Neutrophil collagenase; MMP-8; PMNL-CL; CLG1	Mouse	HEK293
	MMP-8 protein degrades different fibrillar collagens, such as type I, II, and III. It is implicated in the breakdown of collagen fibers during uterine involution. MMP-8 Protein, Mouse (242a.a, HEK293, His) is the recombinant mouse-derived MMP-8 protein, expressed by HEK293, with C-His labeled tag.

HY-P70351A

	MMP-9 Protein, Mouse (HEK293, C-His) 1 Publications Verification rMuMatrix metalloproteinase-9/MMP-9, His; Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB	Mouse	HEK293
	The MMP-9 protein is a matrix metalloproteinase that is critical for local extracellular matrix proteolysis and leukocyte migration.It is suggested that it may be involved in bone osteoclastic resorption.MMP-9 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived MMP-9 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P70351

	MMP-9 Protein, Mouse (HEK293, His, solution) rMuMatrix metalloproteinase-9/MMP-9, His; Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB	Mouse	HEK293
	The MMP-9 protein is a matrix metalloproteinase that is critical for local extracellular matrix proteolysis and leukocyte migration.It is suggested that it may be involved in bone osteoclastic resorption.MMP-9 Protein, Mouse (HEK293, His) is the recombinant mouse-derived MMP-9 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P78175

	MMP-9 Protein, Human (Biotinylated, HEK293, His-Avi) MMP-9; GELB; CLG4B; MANDP2; Gelatinase B	Human	HEK293
	MMP-9 Protein, a matrix metalloproteinase, plays a crucial role in localized extracellular matrix breakdown, facilitating leukocyte migration. Its potential involvement in bone osteoclastic resorption is suggested. MMP-9 cleaves KiSS1 and NINJ1, generating their secreted forms. It degrades type IV and type V collagen, producing distinct fragments, and fibronectin, while laminin and Pz-peptide remain unaffected. MMP-9 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived MMP-9 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P73296

	MMP-2 Protein, Human (HEK293) Maximum Cited Publications 8 Publications Verification 72 kDa Type IV Collagenase; Gelatinase A; MMP-2; TBE-1; CLG4A	Human	HEK293
	MMP-2 protein is a multifunctional metalloproteinase that actively participates in physiological processes such as vascular remodeling, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. In addition to degrading extracellular matrix proteins, it also acts on non-matrix proteins to promote vasoconstriction. MMP-2 Protein, Human (HEK293) is the recombinant human-derived MMP-2 protein, expressed by HEK293 , with tag free.

HY-P700793

	MMP-8 Protein, Cynomolgus (HEK293, His) PMNL-CL; CLG1; MMP8; Collagenase 2; PMNL-CL; HNC	Cynomolgus	HEK293
	MMP-8, also known as matrix metalloproteinase-8 or collagenase-2, is recognized for its enzymatic abilities, particularly its ability to break down fibrillar types I, II, and III collagen. This enzymatic activity suggests that MMP-8 plays an important role in the remodeling and turnover of collagen-rich tissues such as connective tissue, cartilage, and bone. MMP-8 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived MMP-8 protein, expressed by HEK293 , with C-His labeled tag.

HY-P73810

	MMP-2 Protein, Mouse (HEK293, His) 72 kDa Type IV Collagenase; Gelatinase A; MMP-2; TBE-1; CLG4A	Mouse	HEK293
	MMP-2 protein is a ubiquitous metalloprotease that contributes to vasculature remodeling, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. In addition to extracellular matrix degradation, it also targets non-matrix proteins and promotes vasoconstriction. MMP-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived MMP-2 protein, expressed by HEK293 , with N-His labeled tag.

HY-P705699

	MMP-2 Protein, Mouse (HEK293, Fc) 72 kDa Type IV Collagenase; Gelatinase A; MMP-2; TBE-1; CLG4A	Mouse	HEK293
	MMP-2 protein is a ubiquitous metalloprotease that contributes to vasculature remodeling, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. In addition to extracellular matrix degradation, it also targets non-matrix proteins and promotes vasoconstriction. MMP-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived MMP-2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P705697

	MMP-2 Protein, Mouse (431a.a, HEK293, His) 72 kDa Type IV Collagenase; Gelatinase A; MMP-2; TBE-1; CLG4A	Mouse	HEK293
	MMP-2 protein is a ubiquitous metalloprotease that contributes to vasculature remodeling, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. In addition to extracellular matrix degradation, it also targets non-matrix proteins and promotes vasoconstriction. MMP-2 Protein, Mouse (431a.a, HEK293, His) is the recombinant mouse-derived MMP-2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P705929

	MMP-9 Protein, Human (Active, Q279R, 601a.a, HEK293, His) Matrix metalloproteinase-9; MMP-9; Gelatinase B; GELB; CLG4B	Human	HEK293
	MMP-9 is an important member of the MMP protein family and regulates the extracellular matrix during physiological processes such as development and tissue remodeling. It involves arthritis and metastasis. MMP-9 Protein, Human (Active, Q279R, 601a.a, HEK293, His) is the recombinant human-derived MMP-9 protein, expressed by HEK293 , with C-His tag.

HY-P700571

	MMP-10 Protein, Human (P. pastoris, His) EC 3.4.24; EC 3.4.24.22; matrix metallopeptidase 10 (stromelysin 2); matrix metalloprotease 10; matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase-10; MMP10; MMP-10; SL-2; STMY2stromelysin-2; Stromelysin 2; transin 2; transin-2	Human	P. pastoris
	MMP-10 protein is a member of the matrix metalloproteinase family and plays a crucial role in extracellular matrix remodeling by promoting the degradation of various substrates. As a protease, MMP-10 is involved in tissue homeostasis, wound healing, and inflammatory responses. MMP-10 Protein, Human (P. pastoris, His) is the recombinant human-derived MMP-10 protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P704541

	MMP-10 Protein, Human (HEK293) EC 3.4.24; EC 3.4.24.22; matrix metallopeptidase 10 (stromelysin 2); matrix metalloprotease 10; matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase-10; MMP10; MMP-10; SL-2; STMY2stromelysin-2; Stromelysin 2; transin 2; transin-2	Human	HEK293
	MMP-10 protein is a member of the matrix metalloproteinase family and plays a crucial role in extracellular matrix remodeling by promoting the degradation of various substrates. As a protease, MMP-10 is involved in tissue homeostasis, wound healing, and inflammatory responses. MMP-10 Protein, Human (Active, HEK293) is the recombinant human-derived MMP-10 protein, expressed by HEK293, with tag free.

HY-P705615

	MMP-7 Protein, Cynomolgus (CHO, His) Matrilysin; Matrin; Matrix metalloproteinase-7; Pump-1 protease; MPSL1; PUMP1	Cynomolgus	CHO
	MMP-7 proteins enzymatically degrade a variety of substrates, including casein, gelatin (types I, III, IV, and V), and fibronectin. Its proteolytic effect activates procollagenase, indicating its role in the regulation of collagen metabolism. MMP-7 Protein, Cynomolgus (CHO, His) is the recombinant human-derived MMP-7 protein, expressed by CHO, with N-His labeled tag.

HY-P703938

	MMP-7 Protein, Human (HEK293, His) Matrilysin; Matrin; Matrix metalloproteinase-7; Pump-1 protease; MPSL1; PUMP1	Human	HEK293
	MMP-7 proteins enzymatically degrade a variety of substrates, including casein, gelatin (types I, III, IV, and V), and fibronectin. Its proteolytic effect activates procollagenase, indicating its role in the regulation of collagen metabolism. MMP-7 Protein, Human (HEK293, His) is the recombinant human-derived MMP-7 protein, expressed by HEK293, with N-His labeled tag.

HY-P702527

	MMP-13 Protein, Human (HEK293) CLG 3; CLG3EC 3.4.24; collagenase 3; EC 3.4.24.-; EC 3.4.24.22; EC 3.4.24.24; EC 3.4.24.35; EC 3.4.24.65; EC 3.4.24.7; MANDP1; matrix metallopeptidase 13 (collagenase 3); matrix metalloproteinase 13 (collagenase 3); Matrix metalloproteinase-13; MMP13; MMP-13	Human	HEK293
	The MMP-13 protein plays a role in the degradation of extracellular matrix proteins, especially fibrillar collagen, fibronectin, TNC, and ACAN. It cleaves triple-helical collagen, preferentially cleaves type II collagen, and can also target other collagen types. MMP-13 Protein, Human (HEK293) is the recombinant human-derived MMP-13 protein, expressed by HEK293 , with tag free.

HY-P71156

	Lipocalin-2/NGAL Protein, Human (HEK293, His) Neutrophil gelatinase-associated lipocalin; NGAL; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; Lipocalin-2; Oncogene 24p3; Siderocalin LCN2; p25; HNL; NGAL	Human	HEK293
	Lipocalin-2/NGAL is an iron transporter that plays a crucial role in various cellular processes. It interacts with the siderophore 2,3-DHBA to transport iron into or out of cells depending on cellular needs. Lipocalin-2/NGAL Protein, Human (HEK293, His) is the recombinant human-derived Lipocalin-2/NGAL protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71934

	Lipocalin-2/NGAL Protein, Human 24p3; 25 kDa alpha 2 microglobulin related subunit of MMP9; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; Alpha 2 microglobulin related protein; HGNC:6526; HNL; Lcn 2; Lcn2; Lipocalin-2; Migration stimulating factor inhibitor; MSFI; Neutrophil gelatinase associated lipocalin; Neutrophil gelatinase associated lipocalin precursor; Neutrophil gelatinase-associated lipocalin; NGAL; NGAL_HUMAN; Oncogene 24p3; Oncogenic lipocalin 24p3; p25; Siderocalin; siderocalin LCN2; SV40 induced 24P3 protein; Uterocalin	Human	E. coli
	Lipocalin-2/NGAL is an iron transporter that plays a crucial role in various cellular processes. It interacts with the siderophore 2,3-DHBA to transport iron into or out of cells depending on cellular needs. Lipocalin-2/NGAL Protein, Human is the recombinant human-derived Lipocalin-2/NGAL protein, expressed by E. coli , with tag free.

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Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

Host:	Mouse (8) Rabbit (25)
Reactivity:	Human (32) Rat (19) Mouse (19) Monkey (2) Rabbit (2) Hamster (4)
Application:	IHC-P (23) ICC/IF (20) IF-Tissue (3) IP (10) IHC-F (3) WB (28) FC (11) ELISA (13)
Isotype:	IgG,Kappa (2) IgG (20) IgG1 (4) IgG2a (3) IgG/Kappa (2) IgG,IgG/Kappa (1)
Conjugation:	Non-conjugated (33) Biotin (1)
Clonality:	Polyclonal (3) Monoclonal (21) Monoclonal Antibody (2) Recombinant (13)
Modification:	Unmodified (27)

Cat. No.	Compare	상품명	Application	Reactivity	Image

HY-P81845

	MMP14 Antibody (YA1590) MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1	WB, IHC-P, ICC/IF, FC, IP	Human, Mouse, Rat
	MMP14 Antibody (YA1590) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP14.

HY-P81845A

	MMP14 Antibody (YA1590)(PBS only) MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1	WB, IHC-P, ICC/IF, FC, IP	Human, Mouse, Rat
	MMP14 Antibody (YA1590) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP14.

HY-P81983

	MMP17 Antibody (YA1728) MMP17; MT4MMP; Matrix metalloproteinase-17; MMP-17; Membrane-type matrix metalloproteinase 4; MT-MMP 4; MTMMP4; Membrane-type-4 matrix metalloproteinase; MT4-MMP; MT4MMP	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	MMP17 Antibody (YA1728) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP17.

HY-P80425

	MMP-9 Antibody (YA285) 1 Publications Verification MMP-9; GELB; MMP9; CLG4B	WB, IHC-P, ICC/IF, FC, IF-Tissue	Human, Rat
	MMP-9 Antibody (YA285) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP-9.

HY-P85767

	MMP2 Antibody (YA5459) MMP2	WB, IHC-P, ICC/IF	Human, Rat, Mouse
	MMP2 Antibody (YA5459) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MMP2.

HY-P80754

	MMP-1 Antibody MMP1; CLG; Interstitial collagenase; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1	WB, IP	Human
	MMP-1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to MMP-1.

HY-P83398

	MMP13 Antibody (YA3143) MMP13; Collagenase 3; Matrix metalloproteinase-13; MMP-13	WB	Human, Mouse
	MMP13 Antibody (YA3143) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP13.

HY-P86592

	MMP13 Antibody (YA6284) MMP13; Collagenase 3; Matrix metalloproteinase-13; MMP-13	WB, IHC-P, ICC/IF, ELISA	Human
	MMP13 Antibody (YA6284) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP13.

HY-P80754A

	MMP-1 Antibody (YA3394) MMP1; CLG; Interstitial collagenase; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1	WB, FC, ICC/IF, IHC-P	Human
	MMP-1 Antibody (YA3394) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP-1.

HY-P84007

	MMP2 Antibody (YA3704) CLG4; MONA; CLG4A; MMP-2; TBE-1; MMP-II	WB, FC, ELISA	Human, Mouse
	MMP2 Antibody (YA3704) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MMP2.

HY-P85280

	MMP-1 Antibody (YA4972) MMP1; CLG; Interstitial collagenase; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1	WB	Human
	MMP-1 Antibody (YA4972) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MMP-1.

HY-P81117

	MMP-7 Antibody 1 Publications Verification Matrilysin; Matrilysin uterine; Matrin; Matrix Metalloproteinase 7; MMP-7; MMP 7; MMP7; MPSL1; PUMP 1; Pump 1 protease; PUMP1; Uterine Matrilysin; Uterine metalloproteinase; MMP7_HUMAN.	IHC-P, IHC-F, ICC/IF, ELISA	Human, Mouse
	MMP-7 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to MMP-7.

HY-P84007A

	MMP2 Antibody (YA3704)(PBS only) CLG4; MONA; CLG4A; MMP-2; TBE-1; MMP-II	WB, FC, ELISA	Human, Mouse
	MMP2 Antibody (YA3704) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MMP2.

HY-P82937

	MMP11 Antibody (YA2682) MMP11; STMY3; Stromelysin-3; SL-3; ST3; Matrix metalloproteinase-11; MMP-11	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	MMP11 Antibody (YA2682) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP11.

HY-P86555

	MMP3 Antibody (YA6247) MMP3; STMY1; Stromelysin-1; SL-1; Matrix metalloproteinase-3; MMP-3; Transin-1	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	MMP3 Antibody (YA6247) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP3.

HY-P84101

	MMP-9 Antibody (YA3798) GELB; CLG4B; MMP-9; MANDP2	IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat, Rabbit, Monkey
	MMP-9 Antibody (YA3798) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MMP-9.

HY-P86378

	MMP-7 Antibody (YA6070) MMP7; MPSL1; PUMP1; Matrilysin; Matrin; Matrix metalloproteinase-7; MMP-7; Pump-1 protease; Uterine metalloproteinase	WB, IHC-P, ICC/IF, IP, ELISA	Human
	MMP-7 Antibody (YA6070) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP-7.

HY-P80756

	MMP-9 Antibody 2 Publications Verification MMP9; CLG4B; Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	MMP-9 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to MMP-9.

HY-P80755

	MMP12 Antibody (YA288) Macrophage metalloelastase; MME; 3.4.24.65; Macrophage elastase; ME; hME; Matrix metalloproteinase-12; MMP-12; MMP12; HME	WB, IP	Human, Rat, Hamster
	MMP12 Antibody (YA288) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP12.

HY-P84101A

	MMP-9 Antibody (YA3798)(PBS only) GELB; CLG4B; MMP-9; MANDP2	IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat, Rabbit, Monkey
	MMP-9 Antibody (YA3798) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MMP-9.

HY-P80424

	MMP3 Antibody (YA286)	WB, IHC-P	Human, Mouse, Rat
	MMP3 Antibody (YA286) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP3.

HY-P80509

	MMP2 Antibody (YA287)	WB, IHC-P	Human, Mouse
	MMP2 Antibody (YA287) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP2.

HY-P87877

	MMP-1 Antibody (YA7562)	WB, IHC-P, ICC/IF, IP, ELISA	Human
	MMP-1 Antibody (YA7562) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to MMP-1.

HY-P87884

	MMP9 Antibody (YA7569)	WB, IHC-P, ICC/IF, IP, ELISA	Mouse, Rat
	MMP9 Antibody (YA7569) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to MMP9.

HY-P87348

	MMP12 Antibody (YA7031)	WB, IHC-P, IHC-F, IF-Tissue	Human
	MMP12 Antibody (YA7031) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP12.

HY-P80755A

	MMP12 Antibody (YA288)(PBS only) Macrophage metalloelastase; MME; 3.4.24.65; Macrophage elastase; ME; hME; Matrix metalloproteinase-12; MMP-12; MMP12; HME	WB, IP	Human, Rat, Hamster
	MMP12 Antibody (YA288) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP12.

HY-P86224

	MMP2 Antibody (YA5916) MMP2; CLG4A; 72 kDa type IV collagenase; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; TBE-1	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	MMP2 Antibody (YA5916) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP2.

HY-P84006

	MMP1 Antibody (YA3703) CLG; CLGN	IHC-P, ICC/IF, FC, ELISA	Human
	MMP1 Antibody (YA3703) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MMP1.

HY-P83285

	MMP8 Antibody (YA3030) HNC; CLG1; MMP-8; PMNL-CL; COLLAGENASE I; NEUTROPHIL; matrix metalloproteinase 8	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	MMP8 Antibody (YA3030) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP8.

HY-P84006A

	MMP1 Antibody (YA3703)(PBS only) CLG; CLGN	IHC-P, ICC/IF, FC, ELISA	Human
	MMP1 Antibody (YA3703) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MMP1.

HY-P83495

	MMP26 Antibody (YA3240) Matrix metalloproteinase-26; Endometase; Matrilysin-2	WB	Human, Hamster, Rat
	MMP26 Antibody (YA3240) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP26.

HY-P83495A

	MMP26 Antibody (YA3240)(PBS only) Matrix metalloproteinase-26; Endometase; Matrilysin-2	WB	Human, Hamster, Rat
	MMP26 Antibody (YA3240) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP26.

HY-P86656

	MMP-9 Antibody (YA6348) Matrix metalloproteinase-9 precursor; MMP-9; MMP9; MMP 9; 92 kDa type IV; Collagenase; 92 kDa gelatinase; Gelatinase B; GELB; MMP9_HUMAN; 82 kDa matrix metalloproteinase-9; 92 kDa type IV collagenase; CLG 4B; CLG-4B; CLG4B; Collagenase Type 4 beta; Collagenase Type-4 beta; Collagenase type IV 92 KD; Collagenase type IV 92 KD; EC 3.4.24.35; Gelatinase 92 KD; Gelatinase 92 KD; Gelatinase beta; Gelatinase-beta; GelatinaseB; GELB; Macrophage gelatinase; MANDP2; Matrix metallopeptidase 9(gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); Matrix Metalloproteinase 9; Type V collagenase.	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse, Rat
	MMP-9 Antibody (YA6348) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP-9.

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Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-110397G

KP-457	MMP	Cardiovascular Disease
KP-457 (GMP) is KP-457 (HY-110397) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture.KP-457 is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, with higher selectivity for ADAM17 than for other MMPs and ADAM10, and IC₅₀s are 11.1 nM (ADAM17), 748 nM (ADAM10), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively .

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