MMP12 Antibody (YA7031)

Cat. No.: HY-P87348: Data Sheet User Guide for Antibodies
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MMP12 Antibody (YA7031) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP12.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

MMP12 Antibody (YA7031) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP12.

Host

Rabbit

Clonality

Recombinant

Molecular Weight

Predicted band size: 42 kDa;

Species Reactivity

Human

SwissProt ID

P39900

Immunogen

A synthesized peptide derived from human MMP12

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-500
IHC-F IHC-F: Immunohistochemistry-Frozen	1:100-500
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:100-500

Sensitivity	Endogenous	Purity	affinity purified by Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 10mM TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3

Subcellular Localization：Secreted, extracellular space, extracellular matrix

Expression：
Tissue_Specificity: Found in alveolar macrophages but not in peripheral blood monocytes
Induction: By exposure to bacterial lipopolysaccharides (LPS). Inhibited by dexamethasone

Isoforms & Post-Translational Modification：P39900: 470 amino acids, molecular weight 54002 Da.

Documentation

User Guide for Antibodies (1077 KB)