MMP13-IN-6
MMP13-IN-6 (Compound 10a) is a MMP-13 inhibitor with a Ki value of 40 nM against hMMP-13. MMP13-IN-6 can be used in the research of osteoarthritis and rheumatoid arthritis.
For research use only. We do not sell to patients.
- Formula: C40H45N4O6PS
- Molecular Weight:740.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
MMP13 40 nM (Ki) |
In Vitro
MMP13-IN-6 (20-80% inhibition concentrations; 30 min preincubation) potently inhibits recombinant human MMP-13 (catalytic domain) with a mean Ki value of 40 ± 1.7 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 740.85
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Formula C40H45N4O6PS
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SMILES
O=P(C(NC(OCC1=CC=CC=C1)=O)CSCC2=CC=CC=C2)(CC(C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N)=O)=O)CCCC5=CC=CC=C5)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)