2. Metabolic Enzyme/Protease
  3. MMP
  4. MMP13-IN-6

MMP13-IN-6 (Compound 10a) is a MMP-13 inhibitor with a Ki value of 40 nM against hMMP-13. MMP13-IN-6 can be used in the research of osteoarthritis and rheumatoid arthritis.

For research use only. We do not sell to patients.

MMP13-IN-6

MMP13-IN-6 Chemical Structure

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MMP13-IN-6 Related Antibodies

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MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8 MMP-19

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Description

MMP13-IN-6 (Compound 10a) is a MMP-13 inhibitor with a Ki value of 40 nM against hMMP-13. MMP13-IN-6 can be used in the research of osteoarthritis and rheumatoid arthritis[1].

IC50 & Target[1]

MMP13

40 nM (Ki)

In Vitro

MMP13-IN-6 (20-80% inhibition concentrations; 30 min preincubation) potently inhibits recombinant human MMP-13 (catalytic domain) with a mean Ki value of 40 ± 1.7 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MMP13-IN-6 Related Antibodies
Molecular Weight

740.85

Formula

C40H45N4O6PS
SMILES

O=P(C(NC(OCC1=CC=CC=C1)=O)CSCC2=CC=CC=C2)(CC(C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N)=O)=O)CCCC5=CC=CC=C5)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MMP13-IN-6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MMP13-IN-6MMPMatrix metalloproteinasesMMP-13catalytic Zn2+ ioncatalytic domainrecombinant human MMP-13S1 pocketactive siteCYP inhibitionInhibitorinhibitorinhibit

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MMP13-IN-6
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HY-181698
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