Tubulin/MMP-IN-3
Tubulin/MMP-IN-3 (Compound 15j) is the dual inhibitor for tubulin polymerization and MMP, and inhibits MMP-2 and MMP-9 with IC50 of 21.13 μM and 19.24 μM. Tubulin/MMP-IN-3 inhibits NF-κB signaling pathway, causes mitochondrial dysfunction and the apoptosis through a mitochondrial-dependent pathway. Tubulin/MMP-IN-3 exhibits antiproliferative activity in a variety of cancer cells, arrests the cell cycle at G2/M phase, and exhibits antitumor efficacy in mouse models.
For research use only. We do not sell to patients.
- Formula: C38H41N2O12P
- Molecular Weight:748.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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Molecular Weight 748.71
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Formula C38H41N2O12P
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SMILES
CCOP(OCC)(C(NC1=CC=C(CC(OC2=C(OC)C=CC(/C=C/C(C3=CC(OC)=C(OC)C(OC)=C3)=O)=C2)=O)C=C1)C4=CC([N+]([O-])=O)=CC=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tubulin/MMP-IN-3 Related Classifications
HY-172088 Related Classifications
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