MMP-2/9-IN-2
MMP-2/9-IN-2 (Compound 6k) is a MMP-2 and MMP-9 inhibitor, with IC50 values of 29.27 and 24.87 μM respectively. MMP-2/9-IN-2 exhibits good selective toxicity against multiple human hepatoma cell lines. MMP-2/9-IN-2 induces cell cycle arrest and apoptosis, significantly inhibits cell migration and invasion. MMP-2/9-IN-2 inhibits the phosphorylation of the STAT3 signaling pathway. MMP-2/9-IN-2 shows strong anti-tumor activity in a nude mouse xenograft model of HepG2 liver cancer cells.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C23H31N3O4
- Masse moléculaire:413.51
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Protocole
- Pureté et documentation
-
Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
MMP-2 29.27 μM (IC50) |
MMP-9 24.87 μM (IC50) |
STAT3 |
Chemical Information
-
Masse moléculaire 413.51
-
Formule C23H31N3O4
-
SMILES
O=C(NCCCN(C)C)NC1=CC(/C=C\C2=CC(OC)=CC(OC)=C2)=CC=C1OC
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MMP-2/9-IN-2 Related Classifications
HY-180117 Related Classifications
Powered by Bioz