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  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. MMP17 Antibody (YA1728)

MMP17 Antibody (YA1728)

Cat. No.: HY-P81983
User Guide for Antibodies Technical Support

MMP17 Antibody (YA1728) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP17.

For research use only. We do not sell to patients.

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20 μL In-stock
50 μL In-stock
100 μL In-stock
250 μL   Get quote  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

MMP17 Antibody (YA1728) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP17.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Molecular Weight
Predicted band size: 67 kDa;
Observed band size: 58 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human MMP17 aa150-210/603.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000-1:2000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:100-1:200
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-1:200
Sensitivity Endogenous Purity Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin
Subcellular Localization：Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side; Secreted, extracellular space, extracellular matrix
Expression：
Tissue_specificity:Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types
Isoforms & Post-Translational Modification：Q9ULZ9 has 2 isomers: Q9ULZ9-1: 66653 Da (predicted); Q9ULZ9-2: 57938 Da (predicted).
The precursor is cleaved by a furin endopeptidase
Database

Entrez Gene: 4326 Human ; 23948 Mouse ; 288626 Rat

SwissProt: Q9ULZ9 Human ; Q9R0S3 Mouse ;

OMIM: 602285 Human

Research Field

Cardiovascular
Synonyms
MMP17; MT4MMP; Matrix metalloproteinase-17; MMP-17; Membrane-type matrix metalloproteinase 4; MT-MMP 4; MTMMP4; Membrane-type-4 matrix metalloproteinase; MT4-MMP; MT4MMP
Documentation
User Guide for Antibodies (1077 KB)

MMP17 Antibody (YA1728) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MMP17 Antibody (YA1728)
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