MMP17 Antibody (YA1728)

製品番号: HY-P81983: データシート User Guide for Antibodies
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MMP17 Antibody (YA1728) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP17.

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容量	価格（税別）	在庫状況	数量
20 μL	$146	在庫あり	Estimated Time of Arrival: December 31
50 μL	$222	在庫あり	Estimated Time of Arrival: December 31
100 μL	$360	在庫あり	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

MMP17 Antibody (YA1728) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP17.

Host

Rabbit

Clonality

Recombinant,Monoclonal

分子量

Predicted band size: 67 kDa;

Observed band size: 58 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9ULZ9

Gene ID

4326 [NCBI]

Immunogen

A synthesized peptide derived from human MMP17 aa150-210/603.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Sensitivity	Endogenous	純度	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin

Subcellular Localization：Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side; Secreted, extracellular space, extracellular matrix

Expression：
Tissue_specificity:Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types

Isoforms & Post-Translational Modification：Q9ULZ9 has 2 isomers: Q9ULZ9-1: 66653 Da (predicted); Q9ULZ9-2: 57938 Da (predicted).
The precursor is cleaved by a furin endopeptidase

Database

Entrez Gene: 4326 Human ; 23948 Mouse ; 288626 Rat

SwissProt: Q9ULZ9 Human ; Q9R0S3 Mouse ;

OMIM: 602285 Human

Research Field

Cardiovascular

Synonyms

MMP17; MT4MMP; Matrix metalloproteinase-17; MMP-17; Membrane-type matrix metalloproteinase 4; MT-MMP 4; MTMMP4; Membrane-type-4 matrix metalloproteinase; MT4-MMP; MT4MMP

ドキュメンテーション

User Guide for Antibodies (1077 KB)