2. Recombinant Proteins
  3. Enzymes & Regulators
  4. Matrix Metalloproteinases
  5. MMP-7
  6. MMP-7 Protein, Cynomolgus (CHO, His)

MMP-7 proteins enzymatically degrade a variety of substrates, including casein, gelatin (types I, III, IV, and V), and fibronectin. Its proteolytic effect activates procollagenase, indicating its role in the regulation of collagen metabolism. MMP-7 Protein, Cynomolgus (CHO, His) is the recombinant human-derived MMP-7 protein, expressed by CHO, with N-His labeled tag.

For research use only. We do not sell to patients.

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Description

MMP-7 proteins enzymatically degrade a variety of substrates, including casein, gelatin (types I, III, IV, and V), and fibronectin. Its proteolytic effect activates procollagenase, indicating its role in the regulation of collagen metabolism. MMP-7 Protein, Cynomolgus (CHO, His) is the recombinant human-derived MMP-7 protein, expressed by CHO, with N-His labeled tag.
Species

Cynomolgus
Source

CHO
Tag

N-His
Accession

G7PNJ9 (L21-K270)
Gene ID

102139796
Molecular Construction
N-term
His
MMP7 (L21-K270)
Accession # G7PNJ9
C-term
Protein Length

Full Length of Mature Protein
Synonyms
Matrilysin; Matrin; Matrix metalloproteinase-7; Pump-1 protease; MPSL1; PUMP1
AA Sequence

LPLPREAGGMSELQWKQAQDYLKRFYLYDSETKNANSLEAKLKEMEKFFGLPITGMLNSRIIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHFTVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDPYPFDGPGNTLAHAFAPGPGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK

Predicted Molecular Mass
29.9 kDa
Molecular Weight

Approximately 30-32 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Glycosylation
Yes
Purity

≥ 90%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
SDS (251 KB)

COA (220 KB)

Handling Instructions (2659 KB)

MMP-7 Protein, Cynomolgus (CHO, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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