CL-82198 hydrochloride
Based on 9 publication(s) in Google Scholar
CL-82198 hydrochloride is a selective inhibitor of MMP-13. CL-82198 hydrochloride binds to the entire S1’ pocket of MMP-13, which is the basis of its selectivity against MMP-1, MMP-9, and TACE.
For research use only. We do not sell to patients.
- CAS No.: 1188890-36-9
- Formula: C17H23ClN2O3
- Molecular Weight:338.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) CL-82198 hydrochloride
More- Nat Biomed Eng. 2025 May 16. [Abstract]
- Cell Stem Cell. 2023 May 4;30(5):648-664.e8. [Abstract]
- Nat Commun. 2026 Jun 11. [Abstract]
- Nat Commun. 2022 Jul 11;13(1):4007. [Abstract]
- Mar Drugs. 2023 Jul 31;21(8):433. [Abstract]
- J Cell Physiol. 2019 Sep;234(9):15395-15406. [Abstract]
- Biol Reprod. 2025 Apr 13;112(4):709-727. [Abstract]
- bioRxiv. 2025 Sep 21:2025.09.18.677154. [Abstract]
- Patent. US20240271130A1.
Biological Activity
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MMP13 |
Chemical Information
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CAS No. 1188890-36-9
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Molecular Weight 338.83
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Formula C17H23ClN2O3
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SMILES
O=C(C1=CC2=C(C=CC=C2)O1)NCCCCN3CCOCC3.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (9)
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Journal Impact Factor
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Most Recent
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Nat Biomed Eng
siRNA conjugate with high albumin affinity and degradation resistance for delivery and treatment of arthritis in mice and guinea pigs. [Abstract]2025 May 16. PMID: 40379798 -
Cell Stem Cell
Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal. [Abstract]2023 May 4;30(5):648-664.e8. PMID: 37146584 -
Nat Commun
Bone-derived Osterix+ osteolineage cells are a source of tumor-promoting myofibroblastic cancer-associated fibroblasts in breast cancer. [Abstract]2026 Jun 11. PMID: 42277024 -
Nat Commun
Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance. [Abstract]2022 Jul 11;13(1):4007. PMID: 35817773 -
Mar Drugs
Astaxanthin: A Marine Drug That Ameliorates Cerebrovascular-Damage-Associated Alzheimer's Disease in a Zebrafish Model via the Inhibition of Matrix Metalloprotease-13. [Abstract]2023 Jul 31;21(8):433. PMID: 37623714 -
J Cell Physiol
2019 Sep;234(9):15395-15406. PMID: 30710340 -
Biol Reprod
Collagen turnover during cervical remodeling involves both intracellular and extracellular collagen degradation pathways. [Abstract]2025 Apr 13;112(4):709-727. PMID: 39823285 -
bioRxiv
Myofibroblastic CAFs arising from bone-resident osteoblast precursors retain an osteolineage signature and support breast cancer progression via Osterix-mediated signaling. [Abstract]2025 Sep 21:2025.09.18.677154. PMID: 41279302 -
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CL-82198 hydrochloride Related Classifications
HY-110046 Related Classifications
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