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adenosine A 1 receptors

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Kinase (1) Adenosine Receptor (141) Adenylate Cyclase (3) Akt (1) Antibiotic (1) Apoptosis (17) Aurora Kinase (1) Autophagy (15) Bacterial (1) Calcium Channel (2) Drug Intermediate (1) Drug Metabolite (1) Endogenous Metabolite (36) Environmental Pollutants (1) Epigenetic Reader Domain (1) ERK (1) Fungal (1) HBV (1) HSV (10) Isotope-Labeled Compounds (23) JNK (1) MMP (1) Nucleoside Antimetabolite/Analog (15) p38 MAPK (1) PARP (1) Phosphodiesterase (PDE) (5) PI3K (3) Platelet-activating Factor Receptor (PAFR) (1) Reference Standards (22) SGLT (1) Xanthine Oxidase (1)
By Research Areas:	Cancer (41) Cardiovascular Disease (43) Endocrinology (1) Infection (12) Inflammation/Immunology (43) Metabolic Disease (30) Neurological Disease (60)
Oligonucleotides:	Nucleoside Analogs (1)

166

Inhibitors & Agonists

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Isotope-Labeled Compounds

Oligonucleotides

Adenosine monophosphate Maximum Cited Publications 18 Publications Verification AMP	Endogenous Metabolite Adenosine Receptor HSV	Infection Metabolic Disease
Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

Inosine 15+ Cited Publications	Adenosine Receptor Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A₁ (A₁R) and A_2A (A_2AR) receptors .

Theobromine 1 Publications Verification 3,7-Dimethylxanthine	Adenosine Receptor Endogenous Metabolite	Neurological Disease
Theobromine is a methylxanthine found in cacao beans which can inhibit adenosine receptor A1 (AR1) signaling.

DPCPX 5+ Cited Publications PD 116948	Adenosine Receptor	Cardiovascular Disease
DPCPX (PD 116948), a xanthine derivative, is a highly potent and selective **Adenosine A1 receptor antagonist, with a K_i** of 0.46 nM in ³H-CHA binding to A1 receptors in rat whole brain membranes .

MRS 1754 5+ Cited Publications	Adenosine Receptor	Metabolic Disease Inflammation/Immunology
MRS 1754 is a selective antagonist radioligand for A_2B adenosine receptor with very low affinity for A₁ and A₃ receptors of both humans and rats .

CGS 15943	Adenosine Receptor PI3K	Inflammation/Immunology Cancer
CGS 15943 is an orally bioavailable non-xanthine **Adenosine Receptor antagonist. Its K_i** for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM in transfected CHO cells, respectively. .

Swertisin 2 Publications Verification	Adenosine Receptor HBV SGLT	Infection Neurological Disease Inflammation/Immunology
Swertisin is an oral **adenosine A1 receptor antagonist and an SGLT2 inhibitor. Swertisin has anti-diabetic, antioxidant properties, inhibits HBV**, and improves cognitive and memory impairments in mice .

Capadenoson 5+ Cited Publications BAY 68-4986	Adenosine Receptor	Cardiovascular Disease
Capadenoson is a selective agonist of **adenosine-A1 receptor**.

Adenosine 5'-monophosphate monohydrate Maximum Cited Publications 18 Publications Verification 5'-AMP monohydrate	Endogenous Metabolite Adenosine Receptor HSV	Infection Metabolic Disease
Adenosine 5'-monophosphate monohydrate is an **adenosine A₁ receptor** agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against HSV-1 and HSV-2 .

Vipadenant 1 Publications Verification BIIB-014; CEB-4520	Adenosine Receptor	Neurological Disease
Vipadenant (BIIB-014; CEB-4520) is an **adenosine receptor antagonist, with K_i*s of 1.3 nM and 68 nM for A_2A and A₁,* respectively.

Adenosine monophosphate (Standard) AMP (Standard)	Reference Standards Endogenous Metabolite Adenosine Receptor HSV	Infection Metabolic Disease
Adenosine monophosphate (Standard) is the analytical standard of Adenosine monophosphate (HY-A0181). This product is intended for research and analytical applications. Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

Derenofylline 2 Publications Verification SLV 320	Adenosine Receptor	Cardiovascular Disease
Derenofylline (SLV 320) is a potent, selective and orally active **adenosine A₁ receptor antagonist, with K_i** values of 1 nM, 200 nM and 398 nM for human A₁, A₃ and A_2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats .

Adenosine (Standard) Adenine riboside (Standard); D-adenosine (Standard)	Reference Standards Nucleoside Antimetabolite/Analog Autophagy Apoptosis Endogenous Metabolite	Metabolic Disease Cancer
Adenosine (Standard) is the analytical standard of Adenosine. This product is intended for research and analytical applications. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .

Adenosine monophosphate-13C10,15N5 dilithium AMP-13C10,15N5 dilithium	Isotope-Labeled Compounds Endogenous Metabolite Adenosine Receptor HSV	Infection Metabolic Disease
Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅(AMP- ¹³C₁₀, ¹⁵N₅) is the ¹³C-labeled and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

Adenosine A1 receptor activator T62 1 Publications Verification	Adenosine Receptor	Neurological Disease Inflammation/Immunology
Adenosine A1 receptor activator T62 is an allosteric enhancer of **adenosine A1 receptor*. Adenosine* A1 receptor activator T62 produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain .

Adenosine amine congener ADAC	Adenosine Receptor	Neurological Disease Inflammation/Immunology
Adenosine amine congener (ADAC) is a selective A1 adenosine receptor agonist, can ameliorate noise- and Cisplatin-induced cochlear injury. Adenosine amine congener also has neuroprotective effects .

A2A receptor antagonist 1 CPI-444 analog	Adenosine Receptor	Neurological Disease Cancer
A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both **adenosine A_2A receptor** and A₁ receptor with K_i values of 4 and 264 nM, respectively .

GR79236	Adenosine Receptor	Inflammation/Immunology
GR79236 is a highly potent, selective and orally active **adenosine A1 receptor agonist with a K_i*s of 3.1 nM and 1300 nM for A1 and A2 receptors*, respectively. GR79236 has anti-nociceptive and anti-inflammatory actions .

9-Ethyladenine	Adenosine Receptor	Neurological Disease
9-Ethyladenine is a precursor of competitive antagonists of **adenosine receptors** (A₁, A₂, A₃), with no significant inhibitory effect on adenine phosphoribosyltransferase (APRT). 9-Ethyladenine derivatives have high affinity and selectivity for A₁ (K_i=27 nM), A₂A (K_i=46 nM), and A₃ (K_i=86 nM) receptors. 9-Ethyladenine does not inhibit brain APRT activity, can be used in the study of adenosine receptor-related diseases (such as nervous system diseases) models .

MRS-1706 1 Publications Verification	Adenosine Receptor	Inflammation/Immunology
MRS-1706 is a potent and selective **adenosine A_2B receptor inverse agonist. MRS-1706 has K_i** values of 1.39, 112, 157, and 230 nM for human A_2B, A_2A, A₁ and A₃ receptors respectively. MRS-1706 blocks adenosine-mediated cAMP induction .

8-Cyclopentyl-1,3-dimethylxanthine 1 Publications Verification	Adenosine Receptor	Cardiovascular Disease
8-Cyclopentyl-1,3-dimethylxanthine (Compound 2a) is a selective **adenosine A1 receptor antagonist with K_i*s of 10.9 nM and 1440 nM for A1 receptor* and A2 receptor, respectively .

M1069 1 Publications Verification	Adenosine Receptor	Cancer
M1069 is a selective and orall active, dual A_2A/A_2B adenosine receptor antagonist with a selectivity of >100 fold against the A₁ and A₃ receptors. M1069 counteracts immune-suppressive mechanisms of adenosine, and exhibits anti-tumor activity .

Trabodenoson INO-8875	Adenosine Receptor	Inflammation/Immunology
Trabodenoson (INO-8875), an adenosine mimetic, is a highly selective **Adenosine A1 receptor** agonist. Trabodenoson (INO-8875) is used in the study for Primary Open-Angle Glaucoma .

BAY-545	Adenosine Receptor	Inflammation/Immunology
BAY-545 is a potent and selective A_2B adenosine receptor antagonist, with an IC₅₀ of 59 nM. BAY-545 also exhibits IC₅₀s of 66, 400, 280 nM for human, mouse, rat A_2B adenosine receptor in cells, respectively, and a K_i of 97 nM for human A_2B adenosine receptor, with more selectivity over A₁, A_2A, and A₃ adenosine receptor .

LUF5834	Adenosine Receptor	Others
LUF5834 is a selective A_2B adenosine receptor (A2BR) partial agonist (EC₅₀ = 12 nM). LUF5834 is also a partial *A₁/A_2A* adenosine receptor agonist (lacking selectivity) with K_i values of 2.6 and 28 nM, respectively .

Sulmazole	Adenosine Receptor	Cardiovascular Disease
Sulmazole is a cardiotonic agent. Sulmazole has competitive inhibitory for A1 adenosine receptor. Sulmazole can improve cardiac index and reduce pulmonary capillary wedge pressure .

DMPX 3,7-Dimethyl-1-propargylxanthine	Adenosine Receptor	Neurological Disease
DMPX (3,7-Dimethyl-1-propargylxanthine) is a selective A_2A adenosine receptor (A_2A AR) antagonist that crosses the blood-brain barrier, with a K_i of 11 μM for rat A₂ adenosine receptor and a K_i of 45 μM for rat A₁ adenosine receptor. By blocking A2A receptors in specific brain regions, DMPX protects dopaminergic and GABAergic neurons from mitochondrial dysfunction. DMPX is applicable to research related to depression, Parkinson's disease and Huntington's disease .

Adenosine receptor antagonist 4	Adenosine Receptor	Cancer
Adenosine receptor antagonist 4 (compound 2) is an **adenosine A1 receptor antagonist with a K_i** of 101 nM for human A1 receptor .

Adenosine receptor inhibitor 2	Xanthine Oxidase Adenosine Receptor	Inflammation/Immunology
Adenosine receptor inhibitor 2 (compound 14b) is a potent AR (adenosine receptor) inhibitor. Adenosine receptor inhibitor 2 shows dual affinity toward A₁/A_2A ARs with higher affinity for the A₁- than the A_2AAR. Adenosine receptor inhibitor 2 has K_i values of 52.2 nM for the A₁AR and 167 nM for the A_2AAR .

Neladenoson	Adenosine Receptor	Cardiovascular Disease Neurological Disease Cancer
Neladenoson is a potent and selective **Adenosine A1 Receptor** agonist. Neladenoson is promising for research of heart failure .

Adenosine-d13 Adenine riboside-d₁₃; D-adenosine-d₁₃	Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog Endogenous Metabolite Autophagy Apoptosis	Metabolic Disease Cancer
Adenosine-d₁₃ (Adenine riboside-d₁₃; D-Adenosine-d₁₃) is deuterium labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

KFM19	Adenosine Receptor	Neurological Disease
KFM19 is a potent, selective **Adenosine receptor** (A1-receptor) antagonist, with an IC₅₀ of 50 nM.

Tecadenoson CVT-510	Adenosine Receptor	Cardiovascular Disease Neurological Disease
Tecadenoson (CVT-510) is a selective A1 adenosine receptor agonist.

A1AR antagonist 6	Adenosine Receptor	Neurological Disease
A1AR antagonist 6 (compound 15) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC₅₀ of 6.38 and a pK_i of 7.13 .

Adenosine monophosphate3C10,15N5 AMP-¹³C₁₀,¹⁵N₅	Isotope-Labeled Compounds Endogenous Metabolite Adenosine Receptor HSV	Infection
Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅ (AMP- ¹³C₁₀, ¹⁵N₅) is the ¹³C- and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

Tonapofylline BG 9928	Adenosine Receptor	Cardiovascular Disease Metabolic Disease
Tonapofylline (BG 9928) is an orally active and selective **adenosine A₁ receptor antagonist with a K_i** of 7.4 nM for human adenosine A₁ receptor (hA₁), which displays 915-fold selectivity versus human adenosine A_2A receptor and 12-fold selectivity versus human adenosine A_2B receptor and is used in development for the treatment of heart failure .

Cat. No.	Product Name

HY-L070

Neuroprotective Compound Library

1,748 compounds

Neurodegenerative diseases are characterised by progressive dysfunction and death of neurons, such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis (MS). Neuroprotection is an approach to preserve neurons so that neurons cannot be hurt by different pathological factors in neurodegenerative diseases. Neuroprotectors are some agonists and antagonists targeting some key targets in neuroprotactive signal pathways, such as calcium and sodium channel blockers, GABA receptor agonists, NMDA receptor Antagonists, etc. Current neuroprotectors cannot reverse existing damage, but they may protect against further nerve damage and slow down any degeneration of the central nervous system (CNS) and still play important roles in the treatment of neurodegenerative diseases.

MCE offers a unique collection of 1,748 compounds with potential neuroprotective activities. These compounds mainly act on some key targets in neuroprotetive signal pathways, such as calcium channel, sodium channel, adenosine A1 receptor, etc. MCE Neuroprotective Compopund Library is a useful tool in neuroprotective drug discovery.

Cat. No.	Product Name	Target	Research Area

HY-P5708

Adenoregulin Dermaseptin b2	Antibiotic Fungal Bacterial	Infection
Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .

Cat. No.	Product Name	Chemical Structure

HY-B0228S1

Adenosine-13C5
Adenosine- ¹³C₅ is the ¹³C labeled Adenosine . Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .

HY-B0228S11

Adenosine-15N5

Adenosine- ¹⁵N₅ (Adenine riboside- ¹⁵N₅; D-Adenosine- ¹⁵N₅) is the ¹⁵N labled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .

HY-N0092S2

Inosine-13C5 2 Publications Verification
Inosine- ¹³C₅ is the ¹³C₅ labeled Inosine (HY-N0092). Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A₁ (A₁R) and A_2A (A_2AR) receptors .

HY-A0181S1

Adenosine monophosphate-15N5 dilithium
Adenosine monophosphate- ¹⁵N₅ dilithium is the ¹⁵N labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-A0181S

Adenosine monophosphate-13C10,15N5 dilithium

Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅(AMP- ¹³C₁₀, ¹⁵N₅) is the ¹³C-labeled and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-B0228S13

Adenosine-13C10

Adenosine- ¹³C₁₀ (Adenine riboside- ¹³C₁₀; D-Adenosine- ¹³C₁₀) is ¹³C-labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

HY-B0228S9

Adenosine-13C10,15N5

Adenosine- ¹³C₁₀, ¹⁵N₅ is the ¹³C and ¹⁵N labeled Adenosine (HY-B0228) . Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .

HY-B0228S6

Adenosine-d2
Adenosine-d₂ is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio

HY-B0228S4

Adenosine-1′-13C
Adenosine-1′- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo

HY-B0228S

Adenosine-d1
Adenosine-d is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .

HY-B0228S5

Adenosine-13C
Adenosine- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology,

HY-A0181S3

Adenosine monophosphate-13C10 dilithium
Adenosine monophosphate- ¹³C₁₀ (AMP- ¹³C₁₀) dilithium is ¹³C-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-N0138S1

Theobromine-d3 1 Publications Verification
Theobromine-d₃ is the deuterium labeled Theobromine. Theobromine is a methylxanthine found in cacao beans which can inhibit adenosine receptor A1 (AR1) signaling.

HY-N0092S

Inosine-2,8-d2
Inosine-2,8-d₂ is the deuterium labeled Inosine. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors .

HY-B0004S

Doxofylline-d6
Doxofylline-d₆ is the deuterium labeled Doxofylline. Doxofylline is an antagonist of adenosine A1 receptor which also inhibits phosphodiesterase IV.

HY-A0181S2

Adenosine monophosphate-d12 dilithium
Adenosine monophosphate-d₁₂ (AMP-d₁₂) dilithium is deuterium labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-B0228S12

Adenosine-d13

Adenosine-d₁₃ (Adenine riboside-d₁₃; D-Adenosine-d₁₃) is deuterium labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

HY-A0181S6

Adenosine monophosphate3C10,15N5

Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅ (AMP- ¹³C₁₀, ¹⁵N₅) is the ¹³C- and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-A0181S4

Adenosine monophosphate-13C10,15N5,d12 dilithium

Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅,d₁₂ (AMP- ¹³C₁₀, ¹⁵N₅,d₁₂) dilithium is ¹³C and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

HY-B0228S8

Adenosine-d1-2
Adenosine-d-2 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular phys

HY-B0228S14

Adenosine-d9
Adenosine-d₉ is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio .

HY-B0228S2

Adenosine-2′-13C
Adenosine-2′- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo

HY-N0138S

Theobromine-d6
Theobromine-d₆ is the deuterium labeled Theobromine. Theobromine is a methylxanthine found in cacao beans which can inhibit adenosine receptor A1 (AR1) signaling.

HY-N0092S1

Inosine-13C
Inosine- ¹³C is the ¹³C labeled Inosine. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A₁ (A₁R) and A_2A (A_2AR) receptors .

HY-A0168S

Regadenoson-d3

Regadenoson-d₃ is the deuterium labeled Regadenoson. Regadenoson (CVT-3146) is a potent and selective A2A adenosine receptor agonist, with K_is of 290 and 1120 nM for rat and pig adenosine A2A receptor, respectively. Regadenoson is selective for the adenosine A2A receptor over adenosine A1 and A2B receptors, and shows 13-fold selectivity over the human adenosine A1 receptor. Regadenoson is a vasodilator stress agent has shifted the landscape of vasodilator myocardial perfusion imaging. Regadenoson increases blood-brain barrier (BBB) permeability in rodents .

HY-B0228S7

Adenosine-d1-1
Adenosine-d-1 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular phys

HY-B0228S3

Adenosine-3′-13C
Adenosine-3′- ¹³C is the ¹³C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo

HY-B0004S1

Doxofylline-d4
Doxofylline-d₄ is the deuterium labeled Doxofylline. Doxofylline is an antagonist of adenosine A1 receptor which also inhibits phosphodiesterase IV .

HY-W779021

Adenosine-15N
Adenosine- ¹⁵N (Adenine riboside- ¹⁵N) is ¹⁵N labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .

HY-A0181S5

Adenosine monophosphate-15N5,d12 dilithium

Adenosine monophosphate- ¹⁵N₅,d₁₂ (AMP- ¹⁵N₅,d₁₂) dilithium is deuterium and ¹⁵N labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

Cat. No.	Product Name		Classification

HY-103185A

CCPA hemihydrate 2-Chloro-N6-cyclopentyladenosine hemihydrate		Nucleoside Analogs
CCPA (2-Chloro-N6-cyclopentyladenosine) hemihydrate a highly selective A1 adenosine receptors agonist with a K_i of 0.4 nM. CCPA hemihydrate inhibits adenylate cyclase with an IC₅₀ of 33 nM. CCPA hemihydrate exhibits anti-seizure and cardiacprotective activity. CCPA hemihydrate can be used for the research of seizure and myocardial infarction .

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