A1/A3 AR antagonist 1
A1/A3 AR antagonist 1 (compound 10) is a potent adenosine 1 (A1) and adenosine 3 (A3) receptor dual antagonist with Kis of 36.7 nM, 25.4 nM and 1.47 nM for human A1, human A3 and rat A1, respectively. A1/A3 AR antagonist 1 can be used for researching kidney failure, inflammatory pulmonary diseases, and Alzheimer’s disease.
For research use only. We do not sell to patients.
- CAS No.: 312929-49-0
- Formula: C24H18N2O3S
- Molecular Weight:414.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Adenosine Receptor Isoforms
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Biological Activity
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human A1 36.7 nM (Ki) |
rat A1 1.47 nM (Ki) |
human A3 25.4 nM (Ki) |
Chemical Information
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CAS No. 312929-49-0
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Molecular Weight 414.48
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Formula C24H18N2O3S
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SMILES
COC1=CC=C(C=C1)C(NC2=NC(C3=CC=CC=C3)=C(S2)C(C4=CC=CC=C4)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)