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Cat. No.: HY-118232

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VUF8504

VUF-8504 is a potent and selective adenosine A3 receptor antagonist with K_i value of 0.017, 14 nM for human A3, A1, respectively.

For research use only. We do not sell to patients.

CAS No.: 112575-50-5
Formula: C₂₂H₁₇N₃O₂
Molecular Weight:355.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

VUF8504 Chemical Structure

CAS No.: 112575-50-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

VUF-8504 is a potent and selective adenosine A3 receptor antagonist with K_i value of 0.017, 14 nM for human A3, A1, respectively^[1].

IC₅₀ & Target^[1]

human A3

0.017 nM (Ki)

human A1

14 nM (Ki)

All Adenosine Receptor Isoforms :

Chemical Information

CAS No. 112575-50-5
Molecular Weight 355.39
Formula C₂₂H₁₇N₃O₂
SMILES

O=C(C1=CC=C(C=C1)OC)NC2=NC(C3=NC=CC=C3)=CC4=C2C=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. van Muijlwijk-Koezen JE, et al. A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds. J Med Chem. 1998 Oct 8;41(21):3994-4000. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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VUF8504

All Adenosine Receptor Isoforms