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Referencia número: HY-144115

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A1AR antagonist 1

A1AR antagonist 1 (compound 18g) is a potent A₁ adenosine receptor (AR) antagonist with K_is of 2.08, 6.91, and 31.2 nM for hA1, hA2A and hA2B, respectively.

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No. CAS: 2760128-99-0
Fòrmula: C₁₈H₁₄N₄O
Peso molecular:302.33

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

A1AR antagonist 1 Chemical Structure

No. CAS: 2760128-99-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

A1AR antagonist 1 (compound 18g) is a potent A₁ adenosine receptor (AR) antagonist with K_is of 2.08, 6.91, and 31.2 nM for hA1, hA2A and hA2B, respectively^[1].

Ver todos los productos específicos de isoformas Adenosine Receptor :

Chemical Information

No. CAS 2760128-99-0
Peso molecular 302.33
Fòrmula C₁₈H₁₄N₄O
SMILES

NC1=NC(C2=CC(OC)=CC=C2)=C(C(C3=CC=CC=C3)=N1)C#N
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Val C, et al. Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1 Antagonists. J Med Chem. 2022;65(3):2091-2106. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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A1AR antagonist 1

Ver todos los productos específicos de isoformas Adenosine Receptor

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

A1AR antagonist 1 Related Classifications

HY-144115 Related Classifications

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