2. GPCR/G Protein
  3. Adenosine Receptor
  4. Adenosine A1 receptor activator T62

Adenosine A1 receptor activator T62 

Cat. No.: HY-106199 Purity: 98.93%
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Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor. Adenosine A1 receptor activator T62 produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain.

For research use only. We do not sell to patients.

Adenosine A1 receptor activator T62 Chemical Structure

Adenosine A1 receptor activator T62 Chemical Structure

CAS No. : 40312-34-3

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10 mM * 1 mL in DMSO USD 594 In-stock
Solid
1 mg USD 185 In-stock
5 mg USD 390 In-stock
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Based on 1 publication(s) in Google Scholar

Adenosine A1 receptor activator T62 Related Antibodies

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Description

Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor. Adenosine A1 receptor activator T62 produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].

IC50 & Target

Adenosine A1 receptor[1]
In Vivo

Adenosine A1 receptor activator T62 (0.3-3 μg; intrathecal administration; male SpragueDawley rats) treatment produces a dose-dependent antihypersensitivity effect, with no effect on ambulation or activity level[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male SpragueDawley rats (250 g) after paw incision surgery[1]
Dosage: 0.3 μg, 0.5 μg, 1 μg, and 3 μg
Administration: Intrathecal administration
Result: Produced a dose-dependent antihypersensitivity effect, with no effect on ambulation or activity level. The ED40 (95% confidence interval) was 0.77 (0.63-0.91) μg.
Clinical Trial
Molecular Weight

291.80

Formula

C15H14ClNOS
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=CC=C(Cl)C=C1)C2=C(N)SC3=C2CCCC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 98.93%

COA (246 KB) RP-HPLC (207 KB)

Handling Instructions (2659 KB)
References
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Adenosine A1 receptor activator T62 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adenosine A1 receptor activator T6240312-34-3Adenosine ReceptorP1 receptorEnhancerallostericadenosinehypersensitivityneuropathicantihypersensitivityα2-adrenoceptorsintrathecalInhibitorinhibitorinhibit

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