1. GPCR/G Protein
  2. Adenosine Receptor
  3. KFM19

KFM19 is a potent, selective Adenosine receptor (A1-receptor) antagonist, with an IC50 of 50 nM.

For research use only. We do not sell to patients.

KFM19 Chemical Structure

KFM19 Chemical Structure

CAS No. : 133058-72-7

Size Price Stock Quantity
1 mg USD 555 In-stock
5 mg USD 1110 In-stock
10 mg USD 1450 In-stock
25 mg USD 2180 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Description

KFM19 is a potent, selective Adenosine receptor (A1-receptor) antagonist, with an IC50 of 50 nM.

IC50 & Target

IC50: 50 nM (Adenosine receptor)[1]

Molecular Weight

318.37

Formula

C16H22N4O3

CAS No.
Appearance

Solid

Color

Off-white to pink

SMILES

O=C(N1CCC)N(CCC)C2=C(N=C(C3CC(CC3)=O)N2)C1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (314.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1410 mL 15.7050 mL 31.4100 mL
5 mM 0.6282 mL 3.1410 mL 6.2820 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1410 mL 15.7050 mL 31.4100 mL 78.5250 mL
5 mM 0.6282 mL 3.1410 mL 6.2820 mL 15.7050 mL
10 mM 0.3141 mL 1.5705 mL 3.1410 mL 7.8525 mL
15 mM 0.2094 mL 1.0470 mL 2.0940 mL 5.2350 mL
20 mM 0.1570 mL 0.7852 mL 1.5705 mL 3.9262 mL
25 mM 0.1256 mL 0.6282 mL 1.2564 mL 3.1410 mL
30 mM 0.1047 mL 0.5235 mL 1.0470 mL 2.6175 mL
40 mM 0.0785 mL 0.3926 mL 0.7852 mL 1.9631 mL
50 mM 0.0628 mL 0.3141 mL 0.6282 mL 1.5705 mL
60 mM 0.0523 mL 0.2617 mL 0.5235 mL 1.3087 mL
80 mM 0.0393 mL 0.1963 mL 0.3926 mL 0.9816 mL
100 mM 0.0314 mL 0.1570 mL 0.3141 mL 0.7852 mL
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KFM19 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
KFM19
Cat. No.:
HY-U00251
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