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Cat. No.: HY-110303

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Xanthine amine congener dihydrochloride

Name: Xanthine amine congener dihydrochloride
Brand: MedChemExpress
SKU: HY-110303
Availability: PreOrder

(Synonyms: XAC dihydrochloride)

Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2 receptor antagonist with IC₅₀ values of 1.8 and 114 nM, respectively. Xanthine amine congener acts as a convulsant agent in mice model.

For research use only. We do not sell to patients.

CAS No.: 1962928-23-9
Formula: C₂₁H₃₀Cl₂N₆O₄
Molecular Weight:501.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Xanthine amine congener dihydrochloride Chemical Structure

CAS No.: 1962928-23-9

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Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IC₅₀ & Target

IC50: 1.8 nM (Adenosine A1 receptor)
IC50: 114 nM (Adenosine A2 receptor)^[1]

All Adenosine Receptor Isoforms :

In Vivo

Xanthine amine congener dihydrochloride is more potent as a convulsant than either caffeine or theophyllin in infusion studies at the dosage 39.8 mg/kg. XAC has no effects by administering the drug via an i.p. injection, the seizure threshold >1000 mg/kg^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Mice^[1]
Dosage:

39.8 mg/kg
Administration:

Infusion injection; single dose
Result:

Acted as a convulsant agent than either caffeine or theophyllin.

Chemical Information

CAS No. 1962928-23-9
Molecular Weight 501.41
Formula C₂₁H₃₀Cl₂N₆O₄
SMILES

O=C1N(C(C2=C(N1CCC)N=C(C3=CC=C(C=C3)OCC(NCCN)=O)N2)=O)CCC.Cl.Cl
Synonyms

XAC dihydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. P F Morgan, et al.Potent Convulsant Actions of the Adenosine Receptor Antagonist, Xanthine Amine Congener (XAC). Life Sci. 1989;45(8):719-28 [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Xanthine amine congener dihydrochloride

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Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References

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Xanthine amine congener dihydrochloride

All Adenosine Receptor Isoforms

Biological Activity

Description

IC50 & Target

In Vivo

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs