2. GPCR/G Protein
  3. Adenosine Receptor
  4. Neladenoson

Neladenoson is a potent and selective Adenosine A1 Receptor agonist. Neladenoson is promising for research of heart failure.

For research use only. We do not sell to patients.

Neladenoson

Neladenoson Chemical Structure

CAS No. : 1239234-36-6

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
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100 mg   Get quote  

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Neladenoson Related Antibodies

Top Publications Citing Use of Products

View All Adenosine Receptor Isoform Specific Products:

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Adenosine A1 receptor (A1R) Adenosine A2A receptor (A2AR) Adenosine A2B receptor (A2BR) Adenosine A3 receptor (A3R)

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Description

Neladenoson is a potent and selective Adenosine A1 Receptor agonist. Neladenoson is promising for research of heart failure[1].

Clinical Trial
Molecular Weight

574.12

Formula

C29H24ClN5O2S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N#CC1=C(C2=CC=C(OCCO)C=C2)C(C#N)=C(N3CCCC3)N=C1SCC4=CSC(C5=CC=C(Cl)C=C5)=N4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (87.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7418 mL 8.7090 mL 17.4180 mL
5 mM 0.3484 mL 1.7418 mL 3.4836 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7418 mL 8.7090 mL 17.4180 mL 43.5449 mL
5 mM 0.3484 mL 1.7418 mL 3.4836 mL 8.7090 mL
10 mM 0.1742 mL 0.8709 mL 1.7418 mL 4.3545 mL
15 mM 0.1161 mL 0.5806 mL 1.1612 mL 2.9030 mL
20 mM 0.0871 mL 0.4354 mL 0.8709 mL 2.1772 mL
25 mM 0.0697 mL 0.3484 mL 0.6967 mL 1.7418 mL
30 mM 0.0581 mL 0.2903 mL 0.5806 mL 1.4515 mL
40 mM 0.0435 mL 0.2177 mL 0.4354 mL 1.0886 mL
50 mM 0.0348 mL 0.1742 mL 0.3484 mL 0.8709 mL
60 mM 0.0290 mL 0.1451 mL 0.2903 mL 0.7257 mL
80 mM 0.0218 mL 0.1089 mL 0.2177 mL 0.5443 mL
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Neladenoson Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neladenoson1239234-36-6Adenosine ReceptorP1 receptorHeart Diseasesheart failureInhibitorinhibitorinhibit

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