CGH2466 dihydrochloride
CGH 2466 dihydrochloride is an orally active adenosine A1, A2B and A3 receptor antagonist with the IC50 values of 19 nM, 21 nM, and 80 nM respectively. CGH 2466 dihydrochloride inhibits p38 MAPK (IC50 = 187~ 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). CGH 2466 dihydrochloride displays potent anti-inflammatory effects both in vitro and in vivo, and can be used for research on asthma and chronic obstructive pulmonary disease (COPD).
For research use only. We do not sell to patients.
- CAS No.: 1177618-54-0
- Formula: C14H11Cl4N3S
- Molecular Weight:395.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Adenosine Receptor Isoforms
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Biological Activity
|
A1 19 nM (IC50) |
A2B 21 nM (IC50) |
A3 80 nM (IC50) |
Chemical Information
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CAS No. 1177618-54-0
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Molecular Weight 395.13
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Formula C14H11Cl4N3S
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SMILES
NC1=NC(C2=CC=C(Cl)C(Cl)=C2)=C(C3=CC=NC=C3)S1.Cl.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CGH2466 dihydrochloride Related Classifications
HY-103167 Related Classifications
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