2. Apoptosis Cell Cycle/DNA Damage Metabolic Enzyme/Protease Autophagy
  3. Nucleoside Antimetabolite/Analog Autophagy Endogenous Metabolite Apoptosis
  4. Adenosine-13C

Adenosine-13C  (Synonyms: Adenine riboside-13C; D-Adenosine-13C)

Cat. No.: HY-B0228S5 Purity: ≥99.0%
COA Handling Instructions

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Adenosine-13C is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology,

For research use only. We do not sell to patients.

Adenosine-<sup>13</sup>C Chemical Structure

Adenosine-13C Chemical Structure

CAS No. : 54447-57-3

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1 mg USD 190 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Adenosine-13C:

Adenosine-13C Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Adenosine-13C is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology,

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Adenosine-13C Related Antibodies
Molecular Weight

268.23

Formula

C913CH13N5O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@](O[C@@H]([C@H]1O)[13CH2]O)([H])N2C3=NC=NC(N)=C3N=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.3 mg/mL (124.15 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 6.67 mg/mL (24.87 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7281 mL 18.6407 mL 37.2814 mL
5 mM 0.7456 mL 3.7281 mL 7.4563 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (257 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.7281 mL 18.6407 mL 37.2814 mL 93.2036 mL
5 mM 0.7456 mL 3.7281 mL 7.4563 mL 18.6407 mL
10 mM 0.3728 mL 1.8641 mL 3.7281 mL 9.3204 mL
15 mM 0.2485 mL 1.2427 mL 2.4854 mL 6.2136 mL
20 mM 0.1864 mL 0.9320 mL 1.8641 mL 4.6602 mL
DMSO 25 mM 0.1491 mL 0.7456 mL 1.4913 mL 3.7281 mL
30 mM 0.1243 mL 0.6214 mL 1.2427 mL 3.1068 mL
40 mM 0.0932 mL 0.4660 mL 0.9320 mL 2.3301 mL
50 mM 0.0746 mL 0.3728 mL 0.7456 mL 1.8641 mL
60 mM 0.0621 mL 0.3107 mL 0.6214 mL 1.5534 mL
80 mM 0.0466 mL 0.2330 mL 0.4660 mL 1.1650 mL
100 mM 0.0373 mL 0.1864 mL 0.3728 mL 0.9320 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Adenosine-13C Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adenosine-13C54447-57-3Adenine riboside-13CD-Adenosine-13CNucleoside Antimetabolite/AnalogAutophagyEndogenous MetaboliteApoptosisInhibitorinhibitorinhibit

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