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Cat. No.: HY-116675

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Sulmazole

Sulmazole is a cardiotonic agent. Sulmazole has competitive inhibitory for A1 adenosine receptor. Sulmazole can improve cardiac index and reduce pulmonary capillary wedge pressure.

For research use only. We do not sell to patients.

CAS No.: 73384-60-8
Formula: C₁₄H₁₃N₃O₂S
Molecular Weight:287.34

Storage:

Store at room temperature 3 years.

In solvent -80°C, 2 years , -20°C, 1 year

Sulmazole Chemical Structure

CAS No.: 73384-60-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Bioz

Biological Activity

Description

Sulmazole is a cardiotonic agent. Sulmazole has competitive inhibitory for A1 adenosine receptor. Sulmazole can improve cardiac index and reduce pulmonary capillary wedge pressure^[1].

All Adenosine Receptor Isoforms :

In Vitro

Sulmazole has competitive inhibitory for A1 adenosine receptors^[1].
Sulmazole attenuates the capacity of GTP to inhibit adenylate cyclase activity and covalent modification of Gi by pertussis toxin treatment abolishes the capacity of sulmazole to mediate stimulation^[1].
Sulmazole has stimulatory effect on adenylate cyclase activity in pertussis toxin-treated membranes^[1].
Sulmazole mediates increases in cAMP accumulation by mechanisms other than phosphodiesterase inhibition, including A1 adenosine receptor antagonism and inhibition of Gi function^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 73384-60-8
Appearance Solid
Molecular Weight 287.34
Formula C₁₄H₁₃N₃O₂S
Color White to off-white
SMILES

O=S(C)C1=CC=C(C(OC)=C1)C2=NC3=NC=CC=C3N2
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. W J Parsons, et al. The new cardiotonic agent sulmazole is an A1 adenosine receptor antagonist and functionally blocks the inhibitory regulator, Gi. Mol Pharmacol. 1988 Apr;33(4):441-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- In Vitro
Chemical Information
Purity & Documentation
References

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Sulmazole

High-Throughput Bioactive Compound Library

All Adenosine Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Sulmazole Related Classifications

HY-116675 Related Classifications