Sulmazole
Sulmazole is a cardiotonic agent. Sulmazole has competitive inhibitory for A1 adenosine receptor. Sulmazole can improve cardiac index and reduce pulmonary capillary wedge pressure.
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- CAS No.: 73384-60-8
- Formule: C14H13N3O2S
- Masse moléculaire:287.34
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Stockage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Activité biologique
Description
In Vitro
Sulmazole has competitive inhibitory for A1 adenosine receptors[1].
Sulmazole attenuates the capacity of GTP to inhibit adenylate cyclase activity and covalent modification of Gi by pertussis toxin treatment abolishes the capacity of sulmazole to mediate stimulation[1].
Sulmazole has stimulatory effect on adenylate cyclase activity in pertussis toxin-treated membranes[1].
Sulmazole mediates increases in cAMP accumulation by mechanisms other than phosphodiesterase inhibition, including A1 adenosine receptor antagonism and inhibition of Gi function[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 73384-60-8
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Appearance Solid
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Masse moléculaire 287.34
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Formule C14H13N3O2S
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Color White to off-white
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SMILES
O=S(C)C1=CC=C(C(OC)=C1)C2=NC3=NC=CC=C3N2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Pureté et documentation
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Fiche technique (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)