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Evans' chiral oxazolidinone

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (24) Cardiovascular Disease (15) Endocrinology (2) Infection (52) Inflammation/Immunology (21) Metabolic Disease (15) Neurological Disease (9)
Click Chemistry:	Azide (2)
Oligonucleotides:	Nucleotide Analogs (2)

230

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Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1102

Evans Blue 25+ Cited Publications Direct Blue 53; T-1824; C.I. 23860	EAAT iGluR	Cardiovascular Disease Neurological Disease
Evans Blue (Direct Blue 53) is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Evans Blue is a L-glutamate and kainate receptor-mediated currents inhibitor. Evans Blue has a strong affinity towards serum albumin, making it a high molecular weight protein tracer. Evans Blue is also used to study BBB (blood-brain barrier) permeability .

HY-W002292

L-Homoserine	Endogenous Metabolite	Inflammation/Immunology
L-Homoserine is a nonessential chiral amino acid and the precursor of L-Threonine (HY-N0658) and L-Methionine (HY-N0326). L-Homoserine wide applications in the fields of pharmaceutical, agricultural, cosmetic and fragrance industries .

HY-40135

L-Hydroxyproline 2 Publications Verification (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid	Endogenous Metabolite	Others
L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-14855

Tedizolid 15+ Cited Publications TR 700; Torezolid; DA-7157	Bacterial Antibiotic	Infection
Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.

HY-10392

Sutezolid 4 Publications Verification PNU-100480; U-100480; PF-02341272	Bacterial Antibiotic	Infection
Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis .

HY-111056

UK122 TFA 1 Publications Verification	Ser/Thr Protease	Cancer
UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC₅₀ of 0.2 μM. UK122 shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC₅₀>100 μM). UK122, 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion .

HY-100180

Delpazolid 1 Publications Verification LCB01-0371	Bacterial Antibiotic	Infection
Delpazolid is a novel oxazolidinone antibiotic agent which can inhibit the growth of MSSA and MRSA with a MIC₉₀ of 2 μg/mL for both of them.

HY-W129394

6-Amino-6-deoxy-β-cyclodextrin	Biochemical Assay Reagents	Others
6-Amino-6-deoxy-β-cyclodextrin is a cyclodextrin derivative that can be used to prepare other cyclodextrin derivatives. 6-Amino-6-deoxy-β-cyclodextrin can also be used as a chiral selector for chiral separation of α-amino acid derivatives by capillary electrophoresis .

HY-14507

YK-4-279 5+ Cited Publications	DNA/RNA Synthesis Apoptosis	Cancer
YK-4-279 blocks RNA Helicase A (RHA) binding with EWS-FLI1 (oncogenic protein). YK-4-279 induces apoptosis and shows anti-proliferation activities towards various cancer cells. YK-4-279 has a chiral center and it can be separated into two enantiomers. YK-4-279 can be used for the research of cancer .

HY-40228

(R)-(+)-tert-Butylsulfinamide (R)-2-Methylpropane-2-sulfinamide	Biochemical Assay Reagents	Others
(R)-(+)-tert-Butylsulfinamide ((R)-2-Methylpropane-2-sulfinamide) is a chiral reagent commonly used in the asymmetric synthesis of compounds such as amines, amino acids, and amino alcohols. (R)-(+)-tert-Butylsulfinamide achieves stereoselective reactions by condensing with carbonyl groups to form sulfinyl imine intermediates, and after the reaction, this group can be removed under acidic conditions to obtain the target product .

HY-W012982

3-Amino-2-oxazolidinone 1 Publications Verification AOZ	Drug Metabolite Monoamine Oxidase	Cardiovascular Disease Metabolic Disease
3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone (HY-B1336). 3-Amino-2-oxazolidinone is always be detected as a indicator of furazolidone residues in vivo. 3-Amino-2-oxazolidinone is orally active .

HY-69348

(S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde	Biochemical Assay Reagents Drug Intermediate	Others
(S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is a chiral compound. (S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is commonly used as a chiral intermediate in asymmetric synthesis and has important applications in the field of organic synthesis .

HY-40229

(S)-(-)-tert-Butylsulfinamide S-(-)-T-Butylsulfinimide	Biochemical Assay Reagents	Others
(S)-(-)-tert-Butylsulfinamide (S-(-)-T-Butylsulfinimide) is a compound containing a chiral sulfur atom. (S)-(-)-tert-Butylsulfinamide can be used in the synthesis of other compounds .

HY-100436

Cadazolid ACT-179811	Bacterial Antibiotic	Infection
Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile.

HY-14800

Radezolid 10+ Cited Publications RX-1741	Bacterial Antibiotic	Infection
Radezolid (RX-1741) is a oxazolidinone antibiotic. Radezolid is active against *Staphylococcus, Chlamydia, and Legionella* species, and remains active against Linezolid-resistant strains .

HY-41882

(S)-4-Benzyl-2-oxazolidone (-)-4-Benzyl-2-oxazolidinone	Biochemical Assay Reagents	Others
(S)-4-Benzyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-139398

TBI-223 1 Publications Verification	Antibiotic Bacterial	Infection
TBI-223 is an orally active oxazolidinone antibiotic and an antimicrobial. TBI-223 shows activity against Mycobacterium tuberculosis (Mtb). TBI-223 exhibits an IC₅₀ of 68 μg/mL for inhibiting mitochondrial protein synthesis (MPS) in HepG2 cells. TBI-223 is effective in three mouse models (bloodstream infection, skin infection, and bone infection) of methicillin-resistant staphylococcus aureus infection. TBI-223 can be used for the study of tuberculosis .

HY-W008325

Boc-L-Dap-OH	Amino Acid Derivatives	Others
Boc-L-Dap-OH is a Boc-protected derivative of L-2,3-diaminopropionic acid. Boc-L-Dap-OH is an important chiral amino acid derivative. Boc-L-Dap-OH can be generated via the Hofmann rearrangement of Boc-L-asparagine. Boc-L-Dap-OH serves as a starting material for the preparation of BIM analogs .

HY-59125

(R,R)-(+)-Hydrobenzoin	Endogenous Metabolite	Others
(R,R)-(+)-Hydrobenzoin is a chiral secondary alcohol that can be used as a key substrate or a chiral auxiliary reagent in various catalytic reactions and synthetic experiments .

HY-I0169

(R)-Amino-N-benzyl-3-methoxypropionamide	Drug Metabolite	Neurological Disease
(R)-Amino-N-benzyl-3-methoxypropionamide is a key intermediate for the synthesis of the antiepileptic agent (R)-Lacosamide. To improve its chiral purity and chemical stability, (R)-Amino-N-benzyl-3-methoxypropionamide can react with phosphoric acid to form a phosphate salt. Detected by high performance liquid chromatography (HPLC), this phosphate salt exhibits extremely high chiral purity, with the content of the R-enantiomer reaching up to 99.37% .

HY-123622

CYMAL-5, 98% (TLC)	Biochemical Assay Reagents	Others
CYMAL-5, 98% (TLC) is a cycloalkyl aliphatic saccharide. CYMAL-5, 98% (TLC) is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5, 98% (TLC) is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .

HY-W002040

(±)-3-Amino-1,2-propanediol, 97% 1-Aminoglycerol, 97%	Drug Intermediate	Others
(±)-3-Amino-1,2-propanediol, 97% (1-Aminoglycerol, 97%) is a chiral raw material that can be used for the synthesis of chiral vanadium (V) Schiff base complexes .

HY-14855A

(S)-Tedizolid 2 Publications Verification (S)-TR 700; (S)-DA 7157	Bacterial Antibiotic	Infection
(S)-Tedizolid is the S-enantiomer of Tedizolid. Tedizolid is a novel oxazolidinone with activity against Gram-positive pathogens. (S)-Tedizolid is the less active isomer.

HY-W127459

2,3-Dipalmitoyl-sn-glycero-1-phosphocholine, 95% D-DPPC, 95%	Liposome	Others
2,3-Dipalmitoyl-sn-glycero-1-phosphocholine, 95% (D-DPPC, 95%) is a chiral phospholipid that serves as a membrane-forming lipid component for bicelle assembly. 2,3-Dipalmitoyl-sn-glycero-1-phosphocholine, 95% can form bicelle assemblies with DHPC, which induce an induced circular dichroism (ICD) signal in the chiral probe DPH, with a polarity opposite to that induced by chiral L-DPPC/DHPC bicelles .

HY-W012982S

*3-Amino-2-oxazolidinone-d4* AOZ-d₄	Isotope-Labeled Compounds Monoamine Oxidase Drug Metabolite	Cardiovascular Disease Metabolic Disease
3-Amino-2-oxazolidinone-d₄ (AOZ-d₄) is a deuterium labeled 3-Amino-2-oxazolidinone (HY-W012982). 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone (HY-B1336). 3-Amino-2-oxazolidinone is always be detected as a indicator of furazolidone residues in vivo. 3-Amino-2-oxazolidinone is orally active .

HY-W002502

(DHQ)2PHAL Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine	Biochemical Assay Reagents	Others
(DHQ)2PHAL (Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine) can be used as a chiral ligand in asymmetric dihydroxylation reactions .

HY-W007664

(R)-4-Benzyl-2-oxazolidinone	Drug Intermediate Cytochrome P450	Cancer
(R)-4-Benzyl-2-oxazolidinone is an oxazolidinone-type auxiliary that enables highly stereoselective asymmetric alkylation reactions. (R)-4-Benzyl-2-oxazolidinone is applied in the total synthesis of natural products and pharmaceutical preparations. Especially in pharmaceutical research and development, (R)-4-Benzyl-2-oxazolidinone not only serves as a key precursor for the synthesis of aromatase inhibitors, but also can be used in studies related to estrogen-dependent breast cancer .

HY-B1871

Metolachlor	Environmental Pollutants Herbicide	Others
Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers .

HY-P10741

DOTA-EB-TATE	Radionuclide-Drug Conjugates (RDCs) Peptide-Drug Conjugates (PDCs) Somatostatin Receptor	Cancer
DOTA-EB-TATE is composed of SST peptide derivative, DOTA-octreotate conjugated a common to an Evans blue analog (EB). DOTA-EB-TATE is a peptide drug conjugate (PDC) improves the pharmacokinetics of SSTR2 analogs and reduces PRRT toxicity. DOTA-EB-TATE can also be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

HY-I0606B

(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde	Drug Intermediate Endogenous Metabolite
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is a chiral molecule with potential chiral catalytic activity. It can be used as an intermediate in organic synthesis and plays a key role in the construction of complex molecular systems. This compound has also been used to develop new compound carriers and exhibits good biocompatibility.

HY-W002062

(S)-4-Isopropyl-2-oxazolidinone	Biochemical Assay Reagents	Others
(S)-4-Isopropyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-70027

*p53 and MDM2 proteins-interaction-inhibitor (chiral)*	MDM-2/p53 E1/E2/E3 Enzyme	Cancer
p53 and MDM2 proteins-interaction-inhibitor (chiral) (Compound 32) is an inhibitor of the interaction between p53 and MDM2 proteins.

HY-W093149

(-)-Menthyloxyacetic acid	Biochemical Assay Reagents	Others
(-)-Menthyloxyacetic acid can be used as a chiral resolving agent .

HY-137025

(S)-NIFE	Amino Acid Derivatives	Others
(S)-NIFE is a chiral derivatizing agent for proteinogenic amino acid analysis .

HY-Y1126

(2S)-2-Pyrrolidinemethanol (S)-(+)-Prolinol; (S)-(+)-Pyrrolidin-2-ylmethanol; (S)-1-(Pyrrolidin-2-yl)methanol	Biochemical Assay Reagents	Others
(2S)-2-Pyrrolidinemethanol ((S)-(+)-Prolinol) reveals binucleophilic character and can be anchored to phthalonitrile derivative from both nitrogen and oxygen atoms. (2S)-2-Pyrrolidinemethanol can be utilized as chiral catalyst .

HY-W021016

(+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane (S,S)-Ph-BPE	Biochemical Assay Reagents	Others
(+)-1,2-Bis ((2S,5S)-2,5-diphenylphospholano)ethane ((S,S)-Ph-BPE) is a chiral bisphosphine ligand and catalyst. (+)-1,2-Bis ((2S,5S)-2,5-diphenylphospholano)ethane acts as a chiral ligand in rhodium-catalyzed reductive hydroformylation of alkenyl boronic esters, enabling enantiodivergent synthesis of chiral γ-boryl alcohols. (+)-1,2-Bis ((2S,5S)-2,5-diphenylphospholano)ethane forms chiral nickel-phosphine complexes to mediate asymmetric hydrogenation of aliphatic γ- and δ-keto acids; protons promote substrate C₌O bond activation and stereoselectivity control via hydrogen bonding. (+)-1,2-Bis ((2S,5S)-2,5-diphenylphospholano)ethane forms a monodentate nickel complex, which serves as the active species for asymmetric hydrogenation of aliphatic keto acids .

HY-153193A

(1R)-LSN3160440	Drug Isomer	Others
(1R)-LSN3160440 is the (1R) chiral isomer of LSN3160440 (HY-153193). LSN3160440 is an allosteric modulator of GLP-1R .

HY-101819

Antibacterial compound 1	Bacterial	Infection
Antibacterial compound 1 is a oxazolidinone extracted from patent WO1999037630A1 with antibacterial activities.

HY-135397

(R)-Linezolid (R)-PNU-100766	Drug Metabolite	Infection
(R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis .

HY-15993

Posizolid AZD2563; AZD5847	Antibiotic	Infection
Posizolid (AZD2563), an oxazolidinone antibiotic, is developed by AstraZeneca for the study of bacterial infections. Posizolid shows very good anti-mycobacterial activity .

HY-136369

Ethofumesate 2 Publications Verification	Environmental Pollutants Herbicide	Others
Ethofumesate, a chiral herbicide, acts by inhibiting mitosis and reducing photosynthesis and plant respiration .

HY-W019727

(S)-4-Phenyloxazolidin-2-one (S)-(+)-4-Phenyl-2-oxazolidinone	Biochemical Assay Reagents	Others
(S)-4-Phenyloxazolidin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-111056A

UK122 hydrochloride 1 Publications Verification	Ser/Thr Protease	Cancer
UK122 hydrochloride is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC₅₀ of 0.2 μM. UK122 hydrochloride shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC₅₀s > 100 μM). UK122 hydrochloride, a 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion .

HY-N16536

(-)-Umtatin	Drug Isomer	Others
(-)-umtatin is a chiral furochromone. (-)-umtatin can be isolated from Ptaeroxylon obliquum (Meliaceae) .

HY-163683

EB-PSMA-617	Radionuclide-Drug Conjugates (RDCs) PSMA	Cancer
EB-PSMA-617 is a modified form of PSMA-617 that has enhanced pharmacokinetic properties by conjugating it to Evans Blue (EB) to extend its circulation half-life to improve prostate tumor uptake and radiotherapy efficacy. In preclinical studies using PC3-PIP-loaded mice, EB-PSMA-617 demonstrated prolonged blood half-life, increased accumulation in PSMA-positive tumors, and successful tumor elimination with lower radioactivity .

HY-W017206

1-Phenyl-2-nitropropene	Drug Intermediate	Others
1-Phenyl-2-nitropropene is the reduction product of acetophenone and can be used to prepare chiral amine compounds .

HY-W012982R

*3-Amino-2-oxazolidinone* (Standard)** AOZ (Standard)	Reference Standards Monoamine Oxidase Drug Metabolite	Cardiovascular Disease Metabolic Disease
3-Amino-2-oxazolidinone (Standard) (AOZ (Standard)) is the analytical standard of 3-Amino-2-oxazolidinone (HY-W012982). This product is intended for research and analytical applications. 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone (HY-B1336). 3-Amino-2-oxazolidinone is always be detected as a indicator of furazolidone residues in vivo. 3-Amino-2-oxazolidinone is orally active .

HY-W098280

Phenylglycine methyl ester	Biochemical Assay Reagents	Others
Phenylglycine methyl ester is a chiral anisotropic reagent. Phenylglycine methyl ester can be used for absolute configuration determination of various chiral carboxylic acids .

HY-116653

Flurtamone	Stearoyl-CoA Desaturase (SCD)	Others
Flurtamone is a chiral herbicide with acute toxicity levels to Selenastrum capricornutum .

HY-167892

DRF-8417	Antibiotic Bacterial	Infection Inflammation/Immunology
DRF-8417, an oxazolidinone antibiotic, is active against Gram-positive and fastidious Gram-negative bacteria. DRF 8417 exhibits potent activity against Gram-positive pathogens with MIC₅₀ and MIC₉₀ values ranging from 0.06 to 1 mg/L .

Cat. No.	Product Name

HY-L903

3D Diverse Fragment Library

5,278 compounds

Fragment-based drug discovery (FBDD) is well suited for discovering both drug leads and chemical probes of protein function. 3-dimensionality (3D) diversity is pivotal because the molecular shape is one of the most important factors in molecular recognition by a biomolecule. There is a developing appreciation that 3D fragments could offer opportunities that are not provided by 2D fragments.

MCE 3D Diverse Fragment Library consists of 5,400 non-flat fragment-like molecules (average Fsp3 value 0.58). More than 4,700 fragment compounds contain at least one chiral center in the structure. The key concepts that underlie the library design were 3D shape, structural diversity, reactive functionality and fragment-like. This 3D Diverse Fragment Library brings higher fragment hit optimization and increases the likelihood to find innovative hits in FBDD.

HY-L944

MCE‑18 Novelty Focused Drug‑Like Library

11028 compounds

MCE 18 stands for Medicinal Chemistry Evolution 2018. This metric was established based on structural data of 28,161 patented lead molecules, 1,370 marketed innovative drugs, and nearly 30,000 investigational candidates from preclinical to Phase III stages across 23 major global pharmaceutical companies from 1950 to 2018. After scaffold clustering analysis, a scoring model was constructed by integrating five three dimensional scaffold characteristics, including aromatic rings (AR), non aromatic heterocycles (NAR), chiral centers (CHIRAL), spirocycles (SPIRO), and the sp³ carbon ratio in cyclic and acyclic moieties, enabling quantitative assessment of molecular scaffold novelty and three dimensional complexity.

According to the score distribution of patented molecules, the top 25% of the original patent dataset was defined as the high novelty region. MCE 18 high scoring compounds selected based on this criterion can effectively avoid scaffold patent conflicts and intellectual property risks from the source. Molecules in this range typically feature a high sp³ carbon ratio, abundant chiral centers, spirocycles, and fused heterocycles with prominent three dimensional conformations. Their spatial properties allow precise matching to complex non traditional undruggable target pockets such as PPI interfaces and allosteric sites, making them ideal structural types for early stage screening of First in class drugs.

MCE‑18 Novelty Focused drug‑Like library strictly selects molecules from the aforementioned high scoring range, containing more than 10,000 premium drug like molecules with highly diverse scaffolds and rich 3D diversity. It can be used for high throughput screening of well established targets such as kinases, GPCRs, and proteases, and is especially suitable for hit identification in allosteric modulation, protein–protein interactions, and various undruggable orphan targets, fully supporting early stage drug discovery for cutting edge innovat

HY-L943

MCE‑18 Novelty drug‑like Library

37030 compounds

MCE-18 stands for Medicinal Chemistry Evolution 2018, which was first published in Journal of Medicinal Chemistry in 2019 for assessing molecular novelty and three-dimensional complexity. Developed based on Clarivate global pharmaceutical patent database, this descriptor was constructed via big-data analysis covering 28,161 patented lead compounds, 1,370 approved drugs and nearly 30,000 preclinical-to-phase III drug candidates from 23 top pharmaceutical companies worldwide between 1950 and 2018, followed by structural clustering and removal of redundant outdated scaffolds for data denoising. Its scoring system integrates five core structural features including aromatic ring (AR), aliphatic heterocycle (NAR), chiral center (CHIRAL), spiro atom (SPIRO), cyclic and acyclic sp³ carbon ratio together with a quadratic topological correction factor. Breaking the limitations of the single Fsp³ parameter, MCE-18 effectively distinguishes conventional flat aromatic scaffolds from modern 3D-enriched novel chemotypes, overcoming typical drawbacks of traditional compound libraries such as scaffold redundancy, low screening hit rates and poor compatibility with allosteric and PPI-related difficult targets.

This library contains over 37,000 structurally diverse compounds with favorable overall drug-likeness, suitable for high-throughput screening against canonical targets including kinases, GPCRs and proteases as well as challenging allosteric and PPI targets. Compounds comply with the developmental trend of modern novel drug discovery, supporting routine primary screening as well as early hit identification of allosteric modulators and PPI inhibitors, serving as an efficient screening resource for early-stage innovative drug discovery.

HY-L0120V

Asinex BioDesign Library

170,269 compounds

“BioDesign” approach incorporates key structural features of known pharmacologically relevant natural products (e.g. alkaloids and other secondary metabolites) into synthetically feasible medicinal chemistry scaffolds. In order to identify the privileged pharmacophores, ring systems and linkers, we have carried out statistical analysis of structural features of natural products, marketed drugs, and drug candidates.

Saturated, fused ring, spiro, and bridged systems with a tendency towards multiple chiral centers are highly privileged among natural products and marketed drugs yet these structures are very poorly represented in commercial libraries. This library addressed this market need by incorporating these privileged elements into the design of novel synthetic molecules with high molecular framework diversity, multiple stereogenic centers (≥2), and degree of saturation (Fsp3 > 0.5).

Cat. No.	Product Name	Type

HY-B1102

Evans Blue

25+ Cited Publications

Direct Blue 53; T-1824; C.I. 23860

Biochemical Assay Reagents

Evans Blue (Direct Blue 53) is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Evans Blue is a L-glutamate and kainate receptor-mediated currents inhibitor. Evans Blue has a strong affinity towards serum albumin, making it a high molecular weight protein tracer. Evans Blue is also used to study BBB (blood-brain barrier) permeability .

HY-40228

(R)-(+)-tert-Butylsulfinamide

(R)-2-Methylpropane-2-sulfinamide

Biochemical Assay Reagents

(R)-(+)-tert-Butylsulfinamide ((R)-2-Methylpropane-2-sulfinamide) is a chiral reagent commonly used in the asymmetric synthesis of compounds such as amines, amino acids, and amino alcohols. (R)-(+)-tert-Butylsulfinamide achieves stereoselective reactions by condensing with carbonyl groups to form sulfinyl imine intermediates, and after the reaction, this group can be removed under acidic conditions to obtain the target product .

HY-Y0816

(S)-Mandelic acid	Biochemical Assay Reagents
(S)-Mandelic Acid is a (S)-enantiomer of Mandelic Acid (HY-W015591). (S)-Mandelic Acid undergoes one-directional chiral inversion to (R)-Mandelic Acid in rat models. (S)-Mandelic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-Y1131

Ethyl (R)-3-hydroxybutyrate Ethyl (R)-3-hydroxybutanoate	Biochemical Assay Reagents
Ethyl (R)-3-hydroxybutyrate is an organic compound commonly used as a starting material for chiral chemical synthesis. It can be used in the preparation of medicines, spices, fine chemicals and food additives, etc., and is widely used in medicine, cosmetics and food industries. In addition, this compound is also used as a substrate or intermediate in some biochemical reactions

HY-69348

(S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde	Biochemical Assay Reagents
(S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is a chiral compound. (S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is commonly used as a chiral intermediate in asymmetric synthesis and has important applications in the field of organic synthesis .

HY-40229

(S)-(-)-tert-Butylsulfinamide S-(-)-T-Butylsulfinimide	Biochemical Assay Reagents
(S)-(-)-tert-Butylsulfinamide (S-(-)-T-Butylsulfinimide) is a compound containing a chiral sulfur atom. (S)-(-)-tert-Butylsulfinamide can be used in the synthesis of other compounds .

HY-W002530

(1S,2R)-1-Aminoindan-2-ol	Biochemical Assay Reagents
(1S,2R)-1-Aminoindan-2-ol is a chiral resolving agent. (1S,2R)-1-Aminoindan-2-ol efficiently resolves various racemic 2-arylalkanoic acids and precisely controls the stereostructure of the products in asymmetric syntheses. (1S,2R)-1-Aminoindan-2-ol can be used in the synthesis of HIV protease inhibitors .

HY-41882

(S)-4-Benzyl-2-oxazolidone (-)-4-Benzyl-2-oxazolidinone	Biochemical Assay Reagents
(S)-4-Benzyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W008325

Boc-L-Dap-OH	Biochemical Assay Reagents
Boc-L-Dap-OH is a Boc-protected derivative of L-2,3-diaminopropionic acid. Boc-L-Dap-OH is an important chiral amino acid derivative. Boc-L-Dap-OH can be generated via the Hofmann rearrangement of Boc-L-asparagine. Boc-L-Dap-OH serves as a starting material for the preparation of BIM analogs .

HY-W016042

N-Cbz-Hydroxy-L-proline	Biochemical Assay Reagents
N-Cbz-Hydroxy-L-proline is a chiral N-Cbz-protected amino acid derivative. N-Cbz-Hydroxy-L-proline is commonly used in the synthesis of polypeptides and pharmaceutical intermediates. N-Cbz-Hydroxy-L-proline undergoes decarboxylation under AlCl₃/HFIP conditions .

HY-I0259

8-Amino-2-naphthol

Biochemical Assay Reagents

8-Amino-2-naphthol is a photoactive charge transfer compounds, which can be used as fluorescent probe. 8-Amino-2-naphthol undergoes excited-state proton transfer (ESPT) to form a zwitterion under acidic conditions, where the photoacidity of its hydroxyl group is regulated by the protonation state of the amino group, enabling pH to act as an on/off switch for photoacidity. 8-Amino-2-naphthol is also utilized as chiral organocatalyst .

HY-123622

CYMAL-5, 98% (TLC)

Biochemical Assay Reagents

CYMAL-5, 98% (TLC) is a cycloalkyl aliphatic saccharide. CYMAL-5, 98% (TLC) is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5, 98% (TLC) is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .

HY-W002040

(±)-3-Amino-1,2-propanediol, 97% 1-Aminoglycerol, 97%	Biochemical Assay Reagents
(±)-3-Amino-1,2-propanediol, 97% (1-Aminoglycerol, 97%) is a chiral raw material that can be used for the synthesis of chiral vanadium (V) Schiff base complexes .

HY-W127459

2,3-Dipalmitoyl-sn-glycero-1-phosphocholine, 95%

D-DPPC, 95%

Biochemical Assay Reagents

2,3-Dipalmitoyl-sn-glycero-1-phosphocholine, 95% (D-DPPC, 95%) is a chiral phospholipid that serves as a membrane-forming lipid component for bicelle assembly. 2,3-Dipalmitoyl-sn-glycero-1-phosphocholine, 95% can form bicelle assemblies with DHPC, which induce an induced circular dichroism (ICD) signal in the chiral probe DPH, with a polarity opposite to that induced by chiral L-DPPC/DHPC bicelles .

HY-W007729

Boc-L-Alaninol	Biochemical Assay Reagents
Boc-L-Alaninol is a Boc-protected chiral amino alcohol. Boc-L-Alaninol can be used in the synthesis of optically active bipyridine-containing polymers .

HY-24312

AD-mix-α

Biochemical Assay Reagents

AD-mix-α is a mixture of organic compounds, commonly used to distinguish and identify asymmetric carbon atoms in chiral compounds. It consists of compounds containing catalytically active metals and chiral ligands. AD-mix-α is widely used in various organic synthesis reactions, such as hydrogenation, addition, and carbonylation reactions, to increase yield and reduce the formation of side reaction products. Although it has no direct application in the medical field, it plays an important role in the pharmaceutical industry and chemical research.

HY-W002878

TsDPEN	Biochemical Assay Reagents
TsDPEN (Compound 2) is a biochemical reagent. TsDPEN derivatives containing N,N,N imide chiral ligands can be applied to copper catalyzed asymmetric Kinugasa reactions .

HY-W005223

(R)-Tetrahydrofuran-2-carboxylic acid (R)-(+)-Tetrahydrofuran-2-carboxylic acid	Biochemical Assay Reagents
(R)-Tetrahydrofuran-2-carboxylic acid is a chiral building block for Faropenem (HY-A0035). Faropenem is a clinically effective non-natural β-lactam antibiotic .

HY-W012846A

L-Threitol L-1,2,3,4-Butanetetrol	Biochemical Assay Reagents
L-Threitol (L-1,2,3,4-Butanetetrol) is a four-carbon sugar alcohol. L-Threitol serves as an important pharmaceutical intermediate and can be used in the synthesis of other active compounds, such as anticancer agents and chiral compounds .

HY-75070

(+)-1-(1-Naphthyl)ethylamine

Biochemical Assay Reagents

(+)-1-(1-Naphthyl)ethylamine ((+)-1-(1-NEA)) is a chiral modifier used to introduce enantioselectivity in catalytic hydrogenation reactions. 1-NEA can undergo H-D exchange with D2 in solution to form N?D bonds. That is, 1-NEA can complete Pt surface adsorption and protonation through amine N atoms, indicating that NEA molecules have the potential to impart enantioselectivity to Pt hydrogenation catalysts .

HY-W010507

(R)-Methyl 3-hydroxybutanoate

Methyl (R)-(-)-3-hydroxybutyrate

Biochemical Assay Reagents

(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.

HY-Y0549

Diphenylacetic acid

Diphenylmethane-α-carboxylic Acid

Biochemical Assay Reagents

Diphenylacetic acid (Diphenylmethane-α-carboxylic Acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Diphenylacetic acid can be used as a reagent in the kinetic resolution of racemic 2-hydroxy-y-butyrolactones by asymmetric esterification in the presence of pivalic anhydride and chiral acyl-transfer catalyst. Diphenylacetic acid can act as a catalyst to synthesize 2-allyl-3-oxazolin-5-one derivatives via Rh-catalyzed coupling reaction of azlactones and alkynes followed by aza-Cope rearrangement .

HY-W002502

(DHQ)2PHAL Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine	Biochemical Assay Reagents
(DHQ)2PHAL (Hydroquinine 1,4-phthalazinediyl diether; 1,4-Bis(dihydroquinine)phthalazine) can be used as a chiral ligand in asymmetric dihydroxylation reactions .

HY-W007664

(R)-4-Benzyl-2-oxazolidinone

Biochemical Assay Reagents

(R)-4-Benzyl-2-oxazolidinone is an oxazolidinone-type auxiliary that enables highly stereoselective asymmetric alkylation reactions. (R)-4-Benzyl-2-oxazolidinone is applied in the total synthesis of natural products and pharmaceutical preparations. Especially in pharmaceutical research and development, (R)-4-Benzyl-2-oxazolidinone not only serves as a key precursor for the synthesis of aromatase inhibitors, but also can be used in studies related to estrogen-dependent breast cancer .

HY-32959

N-Boc-2-pyrroleboronic acid

Biochemical Assay Reagents

N-Boc-2-pyrroleboronic acid is an organic synthesis intermediate used primarily in the synthesis of chiral pharmaceutical molecules and biologically active molecules. The boronic acid on the pyrrole ring can participate in Suzuki coupling reactions. The boronic acid can be oxidized to a hydroxyl group under the action of nitrogen oxides, and after tautomerization, it can be further transformed into 2-oxo-2,5-dihydro-1-pyrrolecarboxylic acid tert-butyl ester .

HY-W010394

Methyl 3-oxopentanoate

Biochemical Assay Reagents

Methyl 3-oxopentanoate, which is also known as diethyl acetylmalonate or MEAM, Methyl 3-oxopentanoate is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings, and it can also Used as a reagent in organic chemical reactions, especially the formation of carbon-carbon bonds through malonate synthesis, the researchers also investigated the potential use of Methyl 3-oxopentanoate in the development of chiral auxiliaries that can aid in the selection of Controlling the stereochemistry of chemical reactions.

HY-W142618

D-Glucal

Biochemical Assay Reagents

D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

HY-40040

(S)-1-Boc-3-methylpiperazine	Biochemical Assay Reagents
(S)-1-Boc-3-methylpiperazine is a synthetic intermediate for indole-piperazine hybrid antimicrobial agent preparation. (S)-1-Boc-3-methylpiperazine can be used for research on bacterial infection and fungal infection .

HY-W002062

(S)-4-Isopropyl-2-oxazolidinone	Biochemical Assay Reagents
(S)-4-Isopropyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W093149

(-)-Menthyloxyacetic acid	Biochemical Assay Reagents
(-)-Menthyloxyacetic acid can be used as a chiral resolving agent .

HY-Y1126

(2S)-2-Pyrrolidinemethanol (S)-(+)-Prolinol; (S)-(+)-Pyrrolidin-2-ylmethanol; (S)-1-(Pyrrolidin-2-yl)methanol	Biochemical Assay Reagents
(2S)-2-Pyrrolidinemethanol ((S)-(+)-Prolinol) reveals binucleophilic character and can be anchored to phthalonitrile derivative from both nitrogen and oxygen atoms. (2S)-2-Pyrrolidinemethanol can be utilized as chiral catalyst .

HY-W012885

(S)-Methyl 3-hydroxybutanoate

Biochemical Assay Reagents

(S)-Methyl 3-hydroxybutanoate consists of a chiral center, resulting in two enantiomers, where (S)-Methyl 3-hydroxybutanoate means that the hydroxyl group is located on the third carbon atom of the S-configuration carboxylic acid group stereoisomers. This compound is often used as a building block for the synthesis of various pharmaceuticals and natural products. Due to its fruity taste, it is also used as a flavor and fragrance ingredient.

HY-W019727

(S)-4-Phenyloxazolidin-2-one (S)-(+)-4-Phenyl-2-oxazolidinone	Biochemical Assay Reagents
(S)-4-Phenyloxazolidin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-34531

4,6-Dichloro-2-methylpyrimidine 2-Methyl-4,6-dichloropyrimidine	Biochemical Assay Reagents
4,6-Dichloro-2-methylpyrimidine (2-Methyl-4,6-dichloropyrimidine) is a chiral catalyst .

HY-78924

N-Boc-D-prolinol	Biochemical Assay Reagents
N-Boc-D-prolinol is a protected chiral proline derivative. N-Boc-D-prolinol facilitates the synthesis of highly selective histamine H₁ and H₃ receptor antagonists. N-Boc-D-prolinol can be used in the research of allergic rhinitis .

HY-W007401

(1R,2S)-1-Amino-2-indanol	Biochemical Assay Reagents
(1R,2S)-1-Amino-2-indanol is a chiral amino-alcohol. (1R,2S)-1-Amino-2-indanol can be used as a chromophore .

HY-Y1126R

(2S)-2-Pyrrolidinemethanol (Standard)

(S)-(+)-Prolinol (Standard); (S)-(+)-Pyrrolidin-2-ylmethanol (Standard); (S)-1-(Pyrrolidin-2-yl)methanol (Standard)

Biochemical Assay Reagents

(2S)-2-Pyrrolidinemethanol (Standard) ((S)-(+)-Prolinol (Standard)) is the analytical standard of (2S)-2-Pyrrolidinemethanol (HY-Y1126). This product is intended for research and analytical applications. (2S)-2-Pyrrolidinemethanol ((S)-(+)-Prolinol) reveals binucleophilic character and can be anchored to phthalonitrile derivative from both nitrogen and oxygen atoms. (2S)-2-Pyrrolidinemethanol can be utilized as chiral catalyst .

HY-W019727R

(S)-4-Phenyloxazolidin-2-one (Standard) (S)-(+)-4-Phenyl-2-oxazolidinone (Standard)	Biochemical Assay Reagents
(S)-4-Phenyloxazolidin-2-one (Standard) is the analytical standard of (S)-4-Phenyloxazolidin-2-one. This product is intended for research and analytical applications. (S)-4-Phenyloxazolidin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127459A

2,3-Dipalmitoyl-sn-glycero-1-phosphocholine, 99%

D-DPPC, 99%

Biochemical Assay Reagents

2,3-Dipalmitoyl-sn-glycero-1-phosphocholine, 99% (D-DPPC, 99%) is a chiral phospholipid that serves as a membrane-forming lipid component for bicelle assembly. 2,3-Dipalmitoyl-sn-glycero-1-phosphocholine, 99% can form bicelle assemblies with DHPC, which induce an induced circular dichroism (ICD) signal in the chiral probe DPH, with a polarity opposite to that induced by chiral L-DPPC/DHPC bicelles .

HY-34061

2-Benzimidazolemethanol 1H-Benzimidazol-2-ylmethanol; 2-(Hydroxymethyl)benzimidazole	Biochemical Assay Reagents
2-Benzimidazolemethanol (1H-Benzimidazol-2-ylmethanol) is a chiral ligand .

HY-W004830

2-Phenyl-1,3-propanediol 2-Phenylpropane-1,3-diol	Biochemical Assay Reagents
2-Phenyl-1,3-propanediol (2-Phenylpropane-1,3-diol) is a chiral ligand .

HY-W005223R

(R)-Tetrahydrofuran-2-carboxylic acid (Standard) (R)-(+)-Tetrahydrofuran-2-carboxylic acid (Standard)	Biochemical Assay Reagents
(R)-Tetrahydrofuran-2-carboxylic acid (Standard) is an analytical standard for (R)-Tetrahydrofuran-2-carboxylic acid (HY-W005223). This product is intended for research and analytical applications. (R)-Tetrahydrofuran-2-carboxylic acid is a chiral building block for Faropenem (HY-A0035). Faropenem is a clinically effective non-natural β-lactam antibiotic .

HY-75920

Inhoffen Lythgoe diol

Biochemical Assay Reagents

Inhoffen Lythgoe diol is an organic molecule commonly used in chiral selective reactions in organic synthesis. It can be used as a catalyst and a ligand, and has a wide range of applications in the preparation of nitrogen- and sulfur-containing natural products, pharmaceuticals, and material science. Inhoffen Lythgoe diol plays a very important role in the field of asymmetric synthesis. Although it has no direct medical application, it plays an important role in the production and research of many important chemicals.

Cat. No.	Product Name	Target	Research Area

HY-Y1080

N-Acetyl-R-leucine N-Acetyl-D-leucine	Amino Acid Derivatives Monocarboxylate Transporter	Endocrinology
N-Acetyl-R-leucine is an amino-protecting group N-substituted chiral amino acid. N-Acetyl-R-leucine is a PepT1 and MCT1 inhibitor with IC₅₀ of 0.74 and 11 mM, respectively. N-Acetyl-R-leucine can be used for LysoTracker signaling studies .

HY-P10741

DOTA-EB-TATE	Radionuclide-Drug Conjugates (RDCs) Peptide-Drug Conjugates (PDCs) Somatostatin Receptor	Cancer
DOTA-EB-TATE is composed of SST peptide derivative, DOTA-octreotate conjugated a common to an Evans blue analog (EB). DOTA-EB-TATE is a peptide drug conjugate (PDC) improves the pharmacokinetics of SSTR2 analogs and reduces PRRT toxicity. DOTA-EB-TATE can also be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W002292

L-Homoserine	Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
L-Homoserine is a nonessential chiral amino acid and the precursor of L-Threonine (HY-N0658) and L-Methionine (HY-N0326). L-Homoserine wide applications in the fields of pharmaceutical, agricultural, cosmetic and fragrance industries .

HY-40135

L-Hydroxyproline 2 Publications Verification (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid	Alkaloids Immune System Disorder Pyrrole Alkaloids Classification of Application Fields Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-N0548

α-Angelica lactone 2 Publications Verification	Natural Products Classification of Application Fields Dicerothamnus rhinocerotis Umbelliferae Plants Disease Research Fields Source Classification Cancer	Glutathione S-transferase
α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes .

HY-134200

1-Palmitoyl-2-oleoyl-sn-glycerol	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
1-Palmitoyl-2-oleoyl-sn-glycerol is a diacylglycerol hormogonium inducer that can be isolated from the coralloid roots of Cycas revoluta. 1-Palmitoyl-2-oleoyl-sn-glycerol promotes the differentiation of filamentous Nostoc cell aggregates into motile hormogonia, and further induces the formation of dense bundle-like structures. 1-Palmitoyl-2-oleoyl-sn-glycerol is not only commonly used as a diacylglycerol standard, but also can effectively identify and separate glycerophosphate-containing phospholipid enantiomers after acetylation. 1-Palmitoyl-2-oleoyl-sn-glycerol is also used to study cyanobacterial developmental mechanisms and lipid analysis .

HY-111664A

(S)-(-)-Citronellal (-)-Citronellal	Structural Classification Classification of Application Fields Citrus limon (L.) Burm. F. Rutaceae Cymbopogon nardus Metabolic Disease Plants Endogenous metabolite Other Monoterpenes Terpenoids Gramineae Disease Research Fields Source Classification	Drug Isomer
(S)-(-)-Citronellal ((-)-Citronellal) is an oxygenated monoterpenoid found in Citrus limon (L.) Burm. F. essential oils. (S)-(-)-Citronellal is a chiral isomers of (R)-(+)-Citronellal (HY-111664) and does not possess microtubule-disrupting activity. (S)-(-)-Citronellal can be used for cancer research .

HY-Y1080

N-Acetyl-R-leucine N-Acetyl-D-leucine	Microorganisms Source Classification	Amino Acid Derivatives Monocarboxylate Transporter
N-Acetyl-R-leucine is an amino-protecting group N-substituted chiral amino acid. N-Acetyl-R-leucine is a PepT1 and MCT1 inhibitor with IC₅₀ of 0.74 and 11 mM, respectively. N-Acetyl-R-leucine can be used for LysoTracker signaling studies .

HY-59125

(R,R)-(+)-Hydrobenzoin	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
(R,R)-(+)-Hydrobenzoin is a chiral secondary alcohol that can be used as a key substrate or a chiral auxiliary reagent in various catalytic reactions and synthetic experiments .

HY-W012874

D-Threonine H-D-Thr-OH	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Fructose-1,6-bisphosphate aldolase Endogenous Metabolite Drug Intermediate
D-Threonine (H-D-Thr-OH) is one of the important unnatural amino acids used as chiral building blocks in pharmaceutical drugs. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde by the catalytic action of D-threonine aldolase .

HY-W008393

(-)-Corey lactone diol	Classification of Application Fields Other Diseases Disease Research Fields	Drug Intermediate
(-)-Corey lactone diol is the reduced form of Corey aldehyde. (-)-Corey lactone diol can be used as a drug intermediate for the synthesis of Beraprost (HY-13569A) .

HY-W015806

3-Pyridineacetic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
3-Pyridineacetic acid is an orally active nicotinic acid analog. 3-Pyridineacetic acid enhances cholesterol oxidation in rat liver mitochondria. 3-Pyridineacetic acid inhibits Triton-induced hypercholesterolemia in rats. 3-Pyridineacetic acid can be used in research related to hypercholesterolemia .

HY-40135R

L-Hydroxyproline (Standard) (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid (Standard)	Alkaloids Structural Classification Immune System Disorder Pyrrole Alkaloids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
L-Hydroxyproline (Standard) is the analytical standard of L-Hydroxyproline. This product is intended for research and analytical applications. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-79334

(S)-(+)-1,2-Propanediol	Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
(S)-(+)-1,2-Propanediol is an endogenous metabolite. (S)-(+)-1,2-Propanediol can be used as an organic solvent and diluent in drug preparations. (S)-(+)-1,2-Propanediol can also be used as a chiral synthetic intermediate and a substrate for enzyme research .

HY-W002292R

L-Homoserine (Standard)	Structural Classification Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
L-Homoserine (Standard) is the analytical standard of L-Homoserine (HY-W002292). This product is intended for research and analytical applications. L-Homoserine is a nonessential chiral amino acid and the precursor of L-Threonine (HY-N0658) and L-Methionine (HY-N0326). L-Homoserine wide applications in the fields of pharmaceutical, agricultural, cosmetic and fragrance industries.

HY-79334R

(S)-(+)-1,2-Propanediol (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
(S)-(+)-1,2-Propanediol (Standard) is the analytical standard of (S)-(+)-1,2-Propanediol. This product is intended for research and analytical applications. (S)-(+)-1,2-Propanediol is an endogenous metabolite. (S)-(+)-1,2-Propanediol can be used as an organic solvent and diluent in drug preparations. (S)-(+)-1,2-Propanediol can also be used as a chiral synthetic intermediate and a substrate for enzyme research.

HY-N0548R

α-Angelica lactone (Standard)	Structural Classification Natural Products Dicerothamnus rhinocerotis Umbelliferae Plants Source Classification	Glutathione S-transferase Reference Standards
α-Angelica lactone (Standard) is the analytical standard of α-Angelica lactone. This product is intended for research and analytical applications. α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes .

HY-N16536

(-)-Umtatin	Structural Classification Natural Products Monophenols Flavonoids Flavones Rutaceae Phenols Plants Source Classification	Drug Isomer
(-)-umtatin is a chiral furochromone. (-)-umtatin can be isolated from Ptaeroxylon obliquum (Meliaceae) .

HY-N15913

ent-DOPC	Lipid	Drug Isomer
ent-DOPC is a glycerol chirality isomer of 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) (HY-113424A) .

HY-N9022

(S)-1-(4-Hydroxy-2,2-dimethylchroman-6-yl)ethanone	Natural Products Plants Compositae Source Classification Tephrosia purpurea (L.) Pers.	Others
(S)-1-(4-Hydroxy-2,2-dimethylchroman-6-yl)ethanone is an enantiopure chiral alcohol. Stereoselective reduction of prochiral ketones is studied by using both cell cultures and wild tissues of various endemic plant species .

HY-59125R

(R,R)-(+)-Hydrobenzoin (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
(R,R)-(+)-Hydrobenzoin (Standard) is the analytical standard of (R,R)-(+)-Hydrobenzoin. This product is intended for research and analytical applications. (R,R)-(+)-Hydrobenzoin is a chiral secondary alcohol that can be used as a key substrate or a chiral auxiliary reagent in various catalytic reactions and synthetic experiments.

HY-N9761

Murrayanine	Alkaloids Pyrrole Alkaloids Rutaceae Murraya koenigii (L.) Spreng Plants Source Classification	Others
Murrayanine is a dimeric pyranoquinoline alkaloid, a mixture of two enantiomers with a predominant configuration on the chiral axis .

HY-W178699

(±)-Neoisomenthol	Structural Classification Other Monoterpenes Philadelphus coronarius L. Terpenoids Hydrangeaceae Plants Source Classification	Drug Derivative
(±)-Neoisomenthol is a monoterpene. (±)-Neoisomenthol is a volatile constituent of Mentha arvensis with a peppermint odor and taste. (±)-Neoisomenthol is a chiral compound, existing as a racemic mixture of two enantiomers, (+)-Neoisomenthol and (-)-Neoisomenthol .

HY-N8275

(R)-(+)-Citronellic acid	Structural Classification Terpenoids Sesquiterpenes Marine natural products Marine microorganism Source Classification	Drug Intermediate
(R)-(+)-Citronellic acid is a chiral carboxylic acid and can be used as a drug intermediate .

HY-W726070

Sedoheptulose	Structural Classification Natural Products Microorganisms Source Classification	Drug Intermediate Endogenous Metabolite
Sedoheptulose is a heptulose. Sedoheptulose, in the form of phosphate esters, functions as a metabolic intermediate in the pentose phosphate pathway. Sedoheptulose serves as a starting material for the chemical synthesis of pseudoaminosugars and chiral substituted furans .

HY-N13470

meso-Astaxanthin	Other Terpenoids Structural Classification Natural Products Animals Terpenoids Source Classification	Drug Isomer
meso-Astaxanthin is a natural stereoisomer of Astaxanthin (HY-B2163) with antioxidant activity and is found in a variety of aquatic animals. meso-Astaxanthin binds to human serum albumin in a monomeric form at a stoichiometric ratio; at low ligand-to-protein ratios, human serum albumin acts as a chiral template for supramolecular assembly at higher ratios. meso-Astaxanthin directly scavenges superoxide anions. meso-Astaxanthin can be used in the research of myocardial ischemia-reperfusion injury .

HY-N12970

14S(15R)-EET	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Others
14S(15R)-EET is an endogenous epoxytrienoic acid derivative that mainly exists in rat organs. By studying its metabolic process, it was found that its stereoselective hydration and formation of chiral diols were significantly affected by epoxidase. Different 14,15-EET enantiomers showed different regions and stereochemistry of hydration reactions, among which 14(R),15(S)-EET showed specific hydration for C15. These findings reveal the important role of epoxidase in the metabolism of endogenous EETs, and the differences in enzyme affinity and reaction rate for individual EET enantiomers may lead to their stereoselective metabolism .

HY-N7469

Glabralide A	Structural Classification Other Monoterpenes Terpenoids Sarcandra glabra (Thunb.) Nakai Other Phenylpropanoids Chloranthaceae Phenylpropanoids Plants Source Classification	Drug Derivative
Glabralide A is a natural chalcone.

HY-N17940

Hemerocallal A	Structural Classification Terpenoids Hemerocallis fulva (L.) L. Diterpenoids Plants Asphodelaceae Source Classification	Others
Hemerocallal A is a diterpenoid compound with a trans-bicyclooctane core, which can be isolated from the dried roots of Hemerocallis fulva (L.) L .

Cat. No.	Product Name	Chemical Structure

HY-40135S

L-Hydroxyproline-d3
L-Hydroxyproline-d₃ is the deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-B1871S

Metolachlor-d6
Metolachlor-d₆ is the deuterium labeled Metolachlor . Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers .

HY-W654232

L-Hydroxyproline-d4
L-Hydroxyproline-d₄ is deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals .

HY-W012982S

*3-Amino-2-oxazolidinone-d4*
3-Amino-2-oxazolidinone-d₄ (AOZ-d₄) is a deuterium labeled 3-Amino-2-oxazolidinone (HY-W012982). 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone (HY-B1336). 3-Amino-2-oxazolidinone is always be detected as a indicator of furazolidone residues in vivo. 3-Amino-2-oxazolidinone is orally active .

HY-10394S1

Linezolid-d8
PNU-100766-d₈ is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .

HY-W750774

(R)-4-Benzyl-3-propionyloxazolidin-2-one-d3
(R)-4-Benzyl-3-propionyloxazolidin-2-one-d₃ (N-3-propionyl-(4R)-benzyl-2-oxazolidinone-d₃) is the deuterium labeled (R)-4-Benzyl-3-propionyloxazolidin-2-one (HY-W008773).

HY-14855S

Tedizolid-13C,d3
Tedizolid- ¹³C,d₃ is the ¹³C- and deuterium labeled Tedizolid. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.

HY-135397S

(R)-Linezolid-d3
(R)-Linezolid-d₃ ((R)-PNU-100766-d₃) is the deuterium labeled (R)-Linezolid. (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis .

HY-10392S

Sutezolid-13C4
Sutezolid- ¹³C₄ (PNU-100480- ¹³C₄) is ¹³C labeled Sutezolid. Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis .

HY-W713975

Metolachlor-d11
Metolachlor-d₁₁ is the deuterium labeled Metolachlor (HY-B1871). Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers .

HY-W012874S

D-Threonine-d2
D-Threonine-d₂ (H-D-Thr-OH-d₂) is the deuterium labeled D-Threonine (HY-W012874). D-Threonine is one of the important unnatural amino acids used as chiral building blocks in pharmaceutical drugs. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde by the catalytic action of D-threonine aldolase.

HY-117068S

(R)-Bromoenol lactone-d7
(R)-Bromoenol lactone-d₇ ((R,E)-Bromoenol lactone-d₇) is deuterium labeled (R)-Bromoenol lactone. (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase γ (iPLA2γ). (R)-BEL inhibits human recombinant iPLA2γ with an IC₅₀ of approximately 0.6 μM .

HY-132672S

*(4S)-3-[(2R)-2-[(2R)-2-(2,4-Difluorophenyl)oxiranyl]-1-oxopropyl]-4-benzyl-2-oxazolidinone-d3*
(4S)-3-[(2R)-2-[(2R)-2-(2,4-Difluorophenyl)oxiranyl]-1-oxopropyl]-4-benzyl-2-oxazolidinone-d₃ is the deuterium labeled (4S)-3-[(2R)-2-[(2R)-2-(2,4-Difluorophenyl)oxiranyl]-1-oxopropyl]-4-benzyl-2-oxazolidinone .

HY-141723S

*(4R,5R)-5-(2,4-Difluorophenyl)-4-methyl-5-(1H-1,2,4-triazol-1-ylmethyl)-2-oxazolidinone-d3*
(4R,5R)-5-(2,4-Difluorophenyl)-4-methyl-5-(1H-1,2,4-triazol-1-ylmethyl)-2-oxazolidinone-d₃ is the deuterium labeled (4R,5R)-5-(2,4-Difluorophenyl)-4-methyl-5-(1H-1,2,4-triazol-1-ylmethyl)-2-oxazolidinone .

HY-W741021

(S)-4-Benzyl-3-propionyloxazolidin-2-one-d3
(S)-4-Benzyl-3-propionyloxazolidin-2-one-d₃ (2-Oxazolidinone, 3-(1-oxopropyl)-4-(phenylmethyl)-, (4S)-d₃) is the deuterium labeled (S)-4-Benzyl-3-propionyloxazolidin-2-one (HY-W008304).

HY-136369S

Ethofumesate-d5
Ethofumesate-d₅ is the deuterium labeled Ethofumesate (HY-136369). Ethofumesate, a chiral herbicide, acts by inhibiting mitosis and reducing photosynthesis and plant respiration .

Cat. No.	Product Name		Classification

HY-151702

(2S)-N3-IsoSer		Azide
(2S)-N3-IsoSer is a click chemistry reagent, a chiral alpha-hydroxypropinoic acid, containing azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151702A

(2S)-N3-IsoSer (DCHA)		Azide
(2S)-N3-IsoSer DCHA is a click chemistry reagent, a chiral alpha-hydroxypropinoic acid, containing azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-F0003

NADPH tetrasodium salt 15+ Cited Publications		Nucleotide Analogs
NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication .

HY-F0003A

NADPH tetracyclohexanamine 15+ Cited Publications		Nucleotide Analogs
NADPH tetracyclohexanamine functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetracyclohexanamine is an endogenous inhibitor of ferroptosis. NADPH tetracyclohexanamine plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication .

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Evans' chiral oxazolidinone

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