1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. (S)-(-)-Propranolol hydrochloride

(S)-(-)-Propranolol hydrochloride 

Cat. No.: HY-B0573A Purity: ≥98.0%
COA Handling Instructions

(S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.

For research use only. We do not sell to patients.

(S)-(-)-Propranolol hydrochloride Chemical Structure

(S)-(-)-Propranolol hydrochloride Chemical Structure

CAS No. : 4199-10-4

Size Price Stock Quantity
50 mg USD 40 In-stock
100 mg USD 65 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (S)-(-)-Propranolol hydrochloride:

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Description

(S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[2].

IC50 & Target

β adrenergic receptor

 

Molecular Weight

295.80

Formula

C16H22ClNO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H](COC1=C2C=CC=CC2=CC=C1)CNC(C)C.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (169.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 10 mg/mL (33.81 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3807 mL 16.9033 mL 33.8066 mL
5 mM 0.6761 mL 3.3807 mL 6.7613 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.3807 mL 16.9033 mL 33.8066 mL 84.5166 mL
5 mM 0.6761 mL 3.3807 mL 6.7613 mL 16.9033 mL
10 mM 0.3381 mL 1.6903 mL 3.3807 mL 8.4517 mL
15 mM 0.2254 mL 1.1269 mL 2.2538 mL 5.6344 mL
20 mM 0.1690 mL 0.8452 mL 1.6903 mL 4.2258 mL
25 mM 0.1352 mL 0.6761 mL 1.3523 mL 3.3807 mL
30 mM 0.1127 mL 0.5634 mL 1.1269 mL 2.8172 mL
DMSO 40 mM 0.0845 mL 0.4226 mL 0.8452 mL 2.1129 mL
50 mM 0.0676 mL 0.3381 mL 0.6761 mL 1.6903 mL
60 mM 0.0563 mL 0.2817 mL 0.5634 mL 1.4086 mL
80 mM 0.0423 mL 0.2113 mL 0.4226 mL 1.0565 mL
100 mM 0.0338 mL 0.1690 mL 0.3381 mL 0.8452 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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(S)-(-)-Propranolol hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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