2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. (S)-(-)-Propranolol hydrochloride

(S)-(-)-Propranolol hydrochloride 

Cat. No.: HY-B0573A Purity: ≥98.0%
COA Handling Instructions

(S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.

For research use only. We do not sell to patients.

(S)-(-)-Propranolol hydrochloride Chemical Structure

(S)-(-)-Propranolol hydrochloride Chemical Structure

CAS No. : 4199-10-4

Size Price Stock Quantity
50 mg USD 40 In-stock
100 mg USD 65 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (S)-(-)-Propranolol hydrochloride:

(S)-(-)-Propranolol hydrochloride Related Antibodies

Top Publications Citing Use of Products

View All Adrenergic Receptor Isoform Specific Products:

View All Isoforms
α adrenergic receptor β adrenergic receptor

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

(S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[2].

IC50 & Target

log Kd: -8.16 (β1-adrenergic receptor)
log Kd: -9.08 (β2-adrenergic receptor)
log Kd: -6.93 (β3-adrenergic receptor)[1]
Molecular Weight

295.80

Appearance

Solid

Formula

C16H22ClNO2
CAS No.
SMILES

O[C@H](COC1=C2C=CC=CC2=CC=C1)CNC(C)C.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (169.03 mM; Need ultrasonic)

H2O : ≥ 10 mg/mL (33.81 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3807 mL 16.9033 mL 33.8066 mL
5 mM 0.6761 mL 3.3807 mL 6.7613 mL
10 mM 0.3381 mL 1.6903 mL 3.3807 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: ≥98.0%

COA (247 KB)

Handling Instructions (2659 KB)
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

(S)-(-)-Propranolol hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

(S)-(-)-Propranolol4199-10-4Adrenergic ReceptorBeta Receptorhypertensionpheochromocytomamyocardial infarctioncardiac arrhythmiasangina pectoris hypertrophic cardiomyopathyInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
(S)-(-)-Propranolol hydrochloride
Cat. No.:
HY-B0573A
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.