4199-10-4
Chemical Structure
(S)-(-)-Propranolol hydrochloride
- CAS No.: 4199-10-4
- Formula:C16H22ClNO2
- Molecular Weight:295.81
IUPAC Name: (S)-1-(isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride
InChIKey: ZMRUPTIKESYGQW-UQKRIMTDSA-N
SMILES: O[C@H](COC1=C2C=CC=CC2=CC=C1)CNC(C)C.[H]Cl
Biological Activity: (S)-(-)-Propranolol hydrochloride is the active isomer of Propranolol (HY-B0573B), with 98-fold greater activity than (R)-(+)-Propranolol. (S)-(-)-Propranolol hydrochloride produces antinociception-related phenotypes in mouse models, accompanied by sedative and ataxic side effects. (S)-(-)-Propranolol hydrochloride can be used in research related to hypertension, myocardial infarction, and pain[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(S)-(-)-Propranolol hydrochloride | 99.97% | (S)-(-)-Propranolol hydrochloride is the active isomer of Propranolol (HY-B0573B), with 98-fold greater activity than (R)-(+)-Propranolol. (S)-(-)-Propranolol hydrochloride produces antinociception-related phenotypes in mouse models, accompanied by sedative and ataxic side effects. (S)-(-)-Propranolol hydrochloride can be used in research related to hypertension, myocardial infarction, and pain. | ||||||||||||||||||||
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References
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[1]. Veloo R A. Synthesis of enantiomerically pure (S)-(-)-propranolol from sorbitol. Tetrahedron: Asymmetry, 1993, 4: 2401-2404.
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[2]. Martin L J, et al. Differences in the Antinociceptive Effects and Binding Properties of Propranolol and Bupranolol Enantiomers. The Journal of Pain, 2015, 16: 1321-1333.
