(S)-BINAP

(S)-BINAP can serve as a chiral ligand in Ru (II) dicarboxylate complexes to catalyze the asymmetric hydrogenation of prochiral α,β- or β,γ-unsaturated carboxylic acids, yielding optically active saturated carboxylic acids and lactones^[1].
(S)-BINAP, as a chiral ligand in Rh (I) cationic complexes, catalyzes the enantioselective isomerization of N,N-diethylgeranylamine (compound 63) and N,N-diethylnerylamine (compound 64) to produce (R)-citronellal (E)-enamine (compound 65) and (S)-citronellal (E)-enamine (compound 65)^[1], respectively.
(S)-BINAP acts as a chiral ligand to catalyze the asymmetric hydrogenation of N-acyl-(Z)-1-alkylidene-1,2,3,4-tetrahydroisoquinoline and γ-chloro β-keto ester 42^[1].
(S)-BINAP can form [(S)-RuCl ((S)-BINAP)(C₆H₆)]Cl [(S)-5a] and [(S)-RuCl ((S)-BINAP)(C₆H₆)]BF₄ [(S)-5d]^[2].
(S)-BINAP-derived catalyst [(S)-RuI ((S)-BINAP)(p-cymene)]I [(S)-10c] catalyzes the asymmetric hydrogenation of methyl (±)-2-(benzamidomethyl)-3-oxobutanoate [(±)-16] to produce syn-(2R,3S)-17; it catalyzes the asymmetric hydrogenation of methyl pyruvate to produce (S)-methyl 2-lactate; it catalyzes the asymmetric hydrogenation of methyl 3-oxobutanoate to produce (S)-methyl 3-hydroxybutanoate; and it catalyzes the asymmetric hydrogenation of geraniol to produce (R)-citronellol^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.