(-)-Menthyloxyacetic acid
Based on 1 Customer Validation
(-)-Menthyloxyacetic acid is a hydrophobic tag that can facilitate the degradation of the CDK9-cyclin T1 protein. Tetraasterane can be used to synthesize LL-K9-3 (HY-156084).
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 40248-63-3
- Formula: C12H22O3
- Molecular Weight:214.31
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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hydrophobic tag |
Chemical Information
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CAS No. 40248-63-3
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Appearance Solid
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Molecular Weight 214.31
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Formula C12H22O3
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Color White to off-white
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SMILES
O=C(O)CO[C@H]1[C@H](C(C)C)CC[C@@H](C)C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Li J, et al. Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer. Journal of medicinal chemistry. 2022 Aug 25;65(16):11034-11057. [Content Brief]
[2]. Lin R, et al. Discovery of HyT-Based Degraders of CDK9-Cyclin T1 Complex. Chemistry & biodiversity. 2023 Aug;20(8):e202300769. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)