40248-63-3
40248-63-3
Chemical Structure
(-)-Menthyloxyacetic acid
- CAS No.: 40248-63-3
- Formula:C12H22O3
- Molecular Weight:214.31
IUPAC Name: 2-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)acetic acid
InChIKey: CILPHQCEVYJUDN-OUAUKWLOSA-N
SMILES: O=C(O)CO[C@H]1[C@H](C(C)C)CC[C@@H](C)C1
Biological Activity: (-)-Menthyloxyacetic acid is a hydrophobic tag that can facilitate the degradation of the CDK9-cyclin T1 protein. Tetraasterane can be used to synthesize LL-K9-3 (HY-156084)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(-)-Menthyloxyacetic acid | 97.0% | (-)-Menthyloxyacetic acid is a hydrophobic tag that can facilitate the degradation of the CDK9-cyclin T1 protein. Tetraasterane can be used to synthesize LL-K9-3 (HY-156084). | ||||||||||||||||||||
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References
- [1]. Li J, et al. Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer. Journal of medicinal chemistry. 2022 Aug 25;65(16):11034-11057. [Content Brief]
- [2]. Lin R, et al. Discovery of HyT-Based Degraders of CDK9-Cyclin T1 Complex. Chemistry & biodiversity. 2023 Aug;20(8):e202300769. [Content Brief]
