(±)-Menthyl acetate
Based on 1 Customer Validation
(±)-Menthyl acetate is a menthol acyl derivative (monoterpene ester) and antibacterial agent found in the essential oil of Mentha arvensis L.. (±)-Menthyl acetate inhibits growth of Gram-positive bacterial strains including Streptococcus mutans, Mycobacterium smegmatis, Enterococcus faecalis, Staphylococcus aureus, and Bacillus subtilis. (±)-Menthyl acetate is inactive against tested fungal strains. (±)-Menthyl acetate can be used in the research of Gram-positive bacterial infections.
For research use only. We do not sell to patients.
- Purity : 99.68%
- CAS No.: 89-48-5
- Formula: C12H22O2
- Molecular Weight:198.31
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Menthyl acetate (Compound 19) (50 μg/disc; 48 h) inhibits the growth of Gram-positive bacterial strains Streptococcus mutans, Mycobacterium smegmatis, Enterococcus faecalis, Staphylococcus aureus, and Bacillus subtilis, with the largest net inhibition zone (15 mm) against Bacillus subtilis, and shows no activity against tested Gram-negative bacterial strains[1].
Menthyl acetate (50 μg/disc; 3-10 days) shows no antifungal activity against tested fungal strains[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 89-48-5
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Appearance Liquid (Density: 0.927±0.10 g/cm3)
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Molecular Weight 198.31
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Formula C12H22O2
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SMILES
[C@H](C)(C)[C@H]1[C@H](OC(C)=O)C[C@H](C)CC1
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (458 KB)
- English - EN (458 KB)
- Français - FR (458 KB)
- Deutsch - DE (458 KB)
- Norwegian - NO (458 KB)
- Español - ES (458 KB)
- Swedish - SV (458 KB)
- Italian - IT (458 KB)
- Korean - KR (458 KB)
- Portuguese - PT (458 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(±)-Menthyl acetate Related Classifications
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