Hydrocinchonidine
Based on 1 Customer Validation
Hydrocinchonidine is an alkaloid that can be used as a chiral base in the 1,3-dipolar cycloaddition reactions of alkenes and azomethine ylides using silver fluoride. Hydrocinchonidine can also be used to synthesize molecules withoptically active quaternary centers via the aza-Henry reaction.
For research use only. We do not sell to patients.
- CAS No.: 485-64-3
- Formula: C19H24N2O
- Molecular Weight:296.41
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
>7.91 μM
Compound: GNF-Pf-1324
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NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
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[PMID: 18579783] |
| Huh-7 | CC50 |
7.91 μM
Compound: GNF-Pf-1324
|
NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
|
[PMID: 18579783] |
Chemical Information
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CAS No. 485-64-3
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Appearance Powder
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Molecular Weight 296.41
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Formula C19H24N2O
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Color White to off-white
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SMILES
O[C@H](C1=CC=NC2=C1C=CC=C2)[C@@]3([H])[N@@](CC4)C[C@H](CC)[C@]4([H])C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Alemparte C, et al., A convenient procedure for the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides and alkenes. Org Lett. 2005 Oct 13;7(21):4569-72. [Content Brief]
[2]. Knudsen KR, et al., A chiral molecular recognition approach to the formation of optically active quaternary centres in aza-Henry reactions. Org Biomol Chem. 2005 Apr 21;3(8):1362-4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hydrocinchonidine Related Classifications
HY-W035708 Related Classifications
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