Sedoheptulose
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Sedoheptulose is a heptulose. Sedoheptulose, in the form of phosphate esters, functions as a metabolic intermediate in the pentose phosphate pathway. Sedoheptulose serves as a starting material for the chemical synthesis of pseudoaminosugars and chiral substituted furans.
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- Purity: 99.46%
- CAS No.: 3019-74-7
- Formula: C7H14O7
- Molecular Weight:210.18
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Sedoheptulose (10% D-ribose; 4 d) is produced at 8.4 mg/mL and 12.3 mg/mL by wild-type Bacillus subtilis IFO 12114 and IFO 13719 T strains, respectively, when cultured at 37°C[1].
Sedoheptulose (15% D-glucose; 4 d) is produced at 4.5 mg/mL by transketolase-deficient Bacillus subtilis mutant strain TK-1 when cultured at 37°C, with accumulation initiating after D-ribose (produced from glucose) is consumed, reaching ~100 mg/mL by 60 h[1].
Sedoheptulose (10% D-glucose plus 5% D-ribose; 4 d) is produced at 25.5 mg/mL by transketolase-deficient Bacillus subtilis mutant strain TK-1 when cultured at 37°C, with scale-up fermentation achieving ~20-25 mg/mL accumulation[1].
Sedoheptulose (15% D-glucose; 4 d) is produced at ~4-6 mg/mL by each of eight transketolase-deficient Bacillus subtilis mutant strains when cultured at 37°C[1].
Sedoheptulose isolated from Bacillus subtilis mutant strain TK-1 fermentation broth is confirmed via multiple analytical methods, with 2.8 g of sedoheptulose syrup recovered and 0.63 g of crystalline sedoheptulosan monohydrate produced from 1.0 g of this syrup[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3019-74-7
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Appearance Oil
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Molecular Weight 210.18
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Formula C7H14O7
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Color Colorless to off-white
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SMILES
O=C(CO)[C@@H](O)[C@H](O)[C@H](O)[C@H](O)CO
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Initial Source
Bacillus subtilis
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Sedoheptulose
- 3019-74-7
- Drug Intermediate
- Endogenous Metabolite
- transketolase-deficient Bacillus subtilis mutant strain TK-1
- pentose phosphate pathway
- D-glucose
- Sedum spectabile
- pseudo amino sugars
- Bacillus subtilis IFO 12114
- Bacillus subtilis IFO 13719 T
- D-ribose
- chirally substituted furans
- ketoheptose
- Inhibitor
- inhibitor
- inhibit