(R)-Bromoenol lactone-d7
(R)-Bromoenol lactone-d7 ((R,E)-Bromoenol lactone-d7) is the deuterated-labeled (R)-Bromoenol lactone (HY-117068). (R)-Bromoenol lactone ((R,E)-Bromoenol lactone) is an isomer of Bromoenol lactone (HY-107411). (R)-Bromoenol lactone acts as a selective inhibitor of microsomal calcium-independent phospholipase A2γ (iPLA2γ). (R)-Bromoenol lactone induces mild activation of p38 mitogen-activated protein kinase in prostate cancer cells, resulting in slight increases in the expressions of phosphorylated p53, total p53 and p21. (R)-Bromoenol lactone is applicable to prostate cancer-related research.
For research use only. We do not sell to patients.
- Formula: C16H6D7BrO2
- Molecular Weight:324.22
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Phospholipase Isoforms
More
Biological Activity
Description
IC50 & Target
|
p38 |
PLA2 |
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled CAS 478288-90-3
-
Molecular Weight 324.22
-
Formula C16H6D7BrO2
-
SMILES
[2H]C1=C(C([2H])=C2C(C([2H])=C(C([2H])=C2[C@@]3(C(O/C(CC3)=C/Br)=O)[H])[2H])=C1[2H])[2H]
-
Synonyms
(R,E)-Bromoenol lactone-d7
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R)-Bromoenol lactone-d7 Related Classifications
HY-117068S Related Classifications
Powered by Bioz
Keywords
- (R)-Bromoenol lactone-d7
- (R,E)-Bromoenol lactone-d7
- Isotope-Labeled Compounds
- Phospholipase
- p38 MAPK
- MDM-2/p53
- prostate cancer cells
- reactive species
- p53
- iPLA2γ
- microsomal calcium-independent phospholipase A2γ
- PC-3 human prostate cancer cells
- phosphorylated-p53
- p21
- p38 mitogen-activated protein kinase
- LNCaP human prostate cancer cells
- Inhibitor
- inhibitor
- inhibit