478288-90-3
Chemical Structure
(R)-Bromoenol lactone
Synonym(s): (R,E)-Bromoenol lactone
- CAS No.: 478288-90-3
- Formula:C16H13BrO2
- Molecular Weight:317.18
IUPAC Name: (R,E)-6-(bromomethylene)-3-(naphthalen-1-yl)tetrahydro-2H-pyran-2-one
InChIKey: BYUCSFWXCMTYOI-HBIYDYFMSA-N
SMILES: O=C1[C@@H](C2=C3C=CC=CC3=CC=C2)CC/C(O1)=C\Br
Biological Activity: (R)-Bromoenol lactone ((R,E)-Bromoenol lactone) is an isomer of Bromoenol lactone (HY-107411). (R)-Bromoenol lactone acts as a selective inhibitor of microsomal calcium-independent phospholipase A2γ (iPLA2γ). (R)-Bromoenol lactone induces mild activation of p38 mitogen-activated protein kinase in prostate cancer cells, resulting in slight increases in the expressions of phosphorylated p53, total p53 and p21. (R)-Bromoenol lactone is applicable to prostate cancer-related research[1].
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(R)-Bromoenol lactone | (R)-Bromoenol lactone ((R,E)-Bromoenol lactone) is an isomer of Bromoenol lactone (HY-107411). (R)-Bromoenol lactone acts as a selective inhibitor of microsomal calcium-independent phospholipase A2γ (iPLA2γ). (R)-Bromoenol lactone induces mild activation of p38 mitogen-activated protein kinase in prostate cancer cells, resulting in slight increases in the expressions of phosphorylated p53, total p53 and p21. (R)-Bromoenol lactone is applicable to prostate cancer-related research. | |||||||||||||||||||||
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(R)-Bromoenol lactone-d7 | (R)-Bromoenol lactone-d7 ((R,E)-Bromoenol lactone-d7) is the deuterated-labeled (R)-Bromoenol lactone (HY-117068). (R)-Bromoenol lactone ((R,E)-Bromoenol lactone) is an isomer of Bromoenol lactone (HY-107411). (R)-Bromoenol lactone acts as a selective inhibitor of microsomal calcium-independent phospholipase A2γ (iPLA2γ). (R)-Bromoenol lactone induces mild activation of p38 mitogen-activated protein kinase in prostate cancer cells, resulting in slight increases in the expressions of phosphorylated p53, total p53 and p21. (R)-Bromoenol lactone is applicable to prostate cancer-related research. | |||||||||||||||||||||
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