478288-90-3
478288-90-3
Chemical Structure
(R)-Bromoenol lactone
Synonym(s): (R,E)-Bromoenol lactone
- CAS No.: 478288-90-3
- Formula:C16H13BrO2
- Molecular Weight:317.18
IUPAC Name: (R,E)-6-(bromomethylene)-3-(naphthalen-1-yl)tetrahydro-2H-pyran-2-one
InChIKey: BYUCSFWXCMTYOI-HBIYDYFMSA-N
SMILES: O=C1[C@@H](C2=C3C=CC=CC3=CC=C2)CC/C(O1)=C\Br
Biological Activity: (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase γ (iPLA2γ). (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 µM[1].
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(R)-Bromoenol lactone | (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase γ (iPLA2γ). (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 µM. | |||||||||||||||||||||
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(R)-Bromoenol lactone-d7 | (R)-Bromoenol lactone-d7 ((R,E)-Bromoenol lactone-d7) is deuterium labeled (R)-Bromoenol lactone. (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase γ (iPLA2γ). (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 μM. | |||||||||||||||||||||
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References
