Amfenac ethyl ester
Amfenac ethyl ester is an orally active cyclooxygenase (COX) inhibitor. Amfenac ethyl ester exhibits antiinflammatory activity in rodent models. Amfenac ethyl ester can be used for the research of inflammation.
For research use only. We do not sell to patients.
- CAS No.: 61941-57-9
- Formula: C17H17NO3
- Molecular Weight:283.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Amfenac ethyl ester (compound 3) weakly inhibits cyclooxygenase with an IC50 of 50 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Evans blue-Carrageenan-induced pleural
effusion rat model[1] -
Dosage:4; 100 mg/kg
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Administration:p.o.; single dose
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Result:Produced a 24% decrease in average pleural fluid volume relative to control rats.
Chemical Information
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CAS No. 61941-57-9
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Molecular Weight 283.32
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Formula C17H17NO3
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SMILES
O=C(CC1=C(N)C(C(C2=CC=CC=C2)=O)=CC=C1)OCC
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Initial Source
Freshwater turtles
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)