2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. 8(S)-HETE

8(S)-HETE  (Synonyms: 8(S)-Hydroxyeicosatetraenoic acid)

Cat. No.: HY-112653 Purity: 99.9%
COA
SDS
Handling Instructions Technical Support

8(S)-HETE (8(S)-Hydroxyeicosatetraenoic acid) is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 μM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.

For research use only. We do not sell to patients.

8(S)-HETE

8(S)-HETE Chemical Structure

CAS No. : 98462-03-4

Size Price Stock Quantity
Solvent
25 μg (312.04 μM * 250 μL in Ethanol) In-stock
Solvent
50 μg (312.04 μM * 500 μL in Ethanol) In-stock

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Based on 1 publication(s) in Google Scholar

Other Forms of 8(S)-HETE:

8(S)-HETE Related Antibodies

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PPARα PPARβ/δ PPARγ PPAR PPARδ

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Description

8(S)-HETE (8(S)-Hydroxyeicosatetraenoic acid) is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 μM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.

Molecular Weight

320.47

Formula

C20H32O3
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CCCCC/C=C\C/C=C/C=C\[C@H](C/C=C\CCCC(O)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Purity & Documentation

Purity: 99.9%

SDS (604 KB)

COA (238 KB) RP-HPLC (263 KB) MS (188 KB)

Handling Instructions (2659 KB)
References
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8(S)-HETE Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

8(S)-HETE98462-03-48(S)-Hydroxyeicosatetraenoic acidPPARPeroxisome proliferator-activated receptorsInhibitorinhibitorinhibit

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