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8(S)-HETE

(Synonyms: 8(S)-Hydroxyeicosatetraenoic acid)
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8(S)-HETE (8(S)-Hydroxyeicosatetraenoic acid) is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 μM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.

For research use only. We do not sell to patients.

  • Purity: 99.9%
  • CAS No.: 98462-03-4
  • Formula: C20H32O3
  • Molecular Weight:320.47
  • Storage:

    Solution, -20°C, 2 years

  • 8(S)-HETE Chemical Structure
  • 8(S)-HETE Chemical Structure
    8(S)-HETE Chemical Structure
CAS No.: 98462-03-4
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

All PPAR Isoforms

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100 mg

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  • 8(S)-HETE Chemical Structure
    8(S)-HETE Chemical Structure
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  • 8(S)-HETE