98462-03-4

8(S)-HETE Chemical Structure
98462-03-4

Chemical Structure

8(S)-HETE

Synonym(s): 8(S)-Hydroxyeicosatetraenoic acid

  • CAS No.: 98462-03-4
  • Formula:C20H32O3
  • Molecular Weight:320.47

IUPAC Name: (S,5Z,9Z,11E,14Z)-8-hydroxyicosa-5,9,11,14-tetraenoic acid

InChIKey: NLUNAYAEIJYXRB-FHBXLWLHSA-N

SMILES: CCCCC/C=C\C/C=C/C=C\[C@H](C/C=C\CCCC(O)=O)O

Biological Activity: 8(S)-HETE (8(S)-Hydroxyeicosatetraenoic acid) is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 μM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.
The product specifications provided below refer solely to the active content of 8(S)-HETE.

Cat. No. Product Name Purity Description Pricing
HY-112653 		8(S)-HETE 99.9% 8(S)-HETE (8(S)-Hydroxyeicosatetraenoic acid) is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 μM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.
The product specifications provided below refer solely to the active content of 8(S)-HETE.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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