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Results for "

immunoglobulins

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (2) ADC Payload (1) Aminopeptidase (1) Amylases (1) Amyloid-β (3) ANGPTL (1) Antibiotic (1) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (5) Bacterial (4) Beta-lactamase (1) Biochemical Assay Reagents (17) c-Kit (1) C-type Lectin-like Receptors (CTLRs) (1) Caspase (1) CCR (1) CD1 (1) CD20 (1) CD276/B7-H3 (1) CD28 (2) CD3 (5) CD47 (1) Claudin (1) Complement System (4) CTLA-4 (3) CXCR (1) Dihydroorotate Dehydrogenase (2) DNA/RNA Synthesis (2) Drug Derivative (2) Drug Intermediate (1) EGFR (1) Endogenous Metabolite (4) Endothelin Receptor (1) Factor VIIa (1) Fc Receptor (FcR) (13) Fluorescent Dye (1) GLP Receptor (1) HBV (2) HIV (1) HSP (2) Human leukocyte immunoglobulin (Ig)-like receptors (LILR) (3) IFNAR (3) IGF-1R (1) Influenza Virus (1) Insulin Receptor (1) Interleukin Related (18) LAG-3 (2) LILRB (2) MHC (1) mRNA (4) Mucin (1) Notch (1) NTPDase (1) Nuclear Factor of activated T Cells (NFAT) (1) Orexin Receptor (OX Receptor) (1) P-selectin (1) PAK (1) PD-1/PD-L1 (7) Phosphodiesterase (PDE) (1) Platelet-activating Factor Receptor (PAFR) (1) Potassium Channel (2) Prostaglandin Receptor (2) Reference Standards (3) SARS-CoV (2) Ser/Thr Protease (2) Sirtuin (2) STAT (1) TGF-beta/Smad (1) TGF-β Receptor (1) Thrombopoietin Receptor (1) Tie (1) Tim3 (2) TNF Receptor (9) Transmembrane Glycoprotein (13) TSH Receptor (1) VEGFR (2) Virus Protease (1) VISTA (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (56) Cardiovascular Disease (7) Endocrinology (2) Infection (11) Inflammation/Immunology (114) Metabolic Disease (11) Neurological Disease (5)
Oligonucleotides:	mRNA (4) Interleukin & Receptors (1)

165

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

108

Inhibitory Antibodies

Natural
Products

Oligonucleotides

Ifinatamab DS-7300a Antibody; MABX-9001A Antibody	CD276/B7-H3	Inflammation/Immunology Cancer
Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur .

Rocatinlimab AMG 451; KHK4083	Orexin Receptor (OX Receptor)	Infection Inflammation/Immunology
Rocatinlimab (AMG 451) (KHK4083) is a fully human immunoglobulin G1 (IgG1) anti-OX40 monoclonal antibody. Rocatinlimab can be used for the research of atopic dermatitis (AD) .

Mosunetuzumab 1 Publications Verification BTCT-4465A; RG-7828; RO7030816	CD20 CD3	Inflammation/Immunology Cancer
Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs) .

Omalizumab 1 Publications Verification Olizumab; rhuMab-E25; IGE25; RG-3648	Interleukin Related	Inflammation/Immunology Cancer
Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a K_D of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a K_D of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research . The component ratio of this product is Active ingredient : Excipients = 1:1.3-1:1.5.

Sibeprenlimab VIS649	SARS-CoV	Inflammation/Immunology Cancer
Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody which inhibits a proliferation-inducing ligand (APRIL). Sibeprenlimab suppresses pathogenic immunoglobulins (IgA and IgM), while preserving antibody responses to mRNA-based vaccines against SARS-COV-2. Sibeprenlimab reduces urinary protein-to-creatinine ratio (UPCR) and glomerular filtration rate (GFR). Sibeprenlimab is promising for the research of IgA nephropathy (IgAN) .

Tiragolumab MTIG-7192A; RG-6058	CD28	Cancer
Tiragolumab is an immune checkpoint inhibitor binding to the T-cell immunoglobulin and ITIM domain (TIGIT). Tiragolumab in combination with Atezolizumab (HY-P9904) and Bevacizumab (HY-P9906) has benefit in unresectable hepatocellular carcinoma. Tiragolumab can be used to study non-small cell lung cancer (NSCLC) and melanoma .

Tozorakimab 1 Publications Verification MEDI-3506	Interleukin Related	Inflammation/Immunology
Tozorakimab (MEDI-3506) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. Tozorakimab reduces inflammation and epithelial dysfunction. Tozorakimab can be used to research chronic obstructive pulmonary disease .

Endoproteinase Glu-C (MS grade) V8 protease; Glu-C	Ser/Thr Protease	Others
Endoproteinase Glu-C (MS grade) is a serine proteinase. Endoproteinase GluC is able to hydrolyze some serpins and all classes of mammalian immunoglobulins .

Lutikizumab ABT-981	Interleukin Related	Inflammation/Immunology
Lutikizumab (ABT-981) is an anti-IL-1α and IL-1β dual variable domain immunoglobulin. Lutikizumab binds and inhibits IL-1α and IL-1β. Lutikizumab can be used for the research of osteoarthritis .

Maridebart AMG133 antibody	ADC Antibody GLP Receptor	Metabolic Disease
Maridebart (AMG133 antibody) is a human immunoglobulin G1-kappa, anti-GIPR (gastric inhibitory polypeptide receptor) monoclonal antibody. Maridebart is the antibody portion of Maridebart cafraglutide (HY-164535) and can be used for the synthesis of antibody-drug conjugates (ADC). Maridebart can be used for the reserrch of obesity and type 2 diabetes .

Protein A 1 Publications Verification SPA	Endogenous Metabolite Apoptosis	Inflammation/Immunology
Protein A (SPA) is an immunoglobulin (Ig)-binding protein that exists on the bacterial surface and can be freely secreted into the extracellular environment. Protein A blocks opsonophagocytosis and induces B cell apoptosis in vitro by binding to the Fc region of antibodies and the Fab region of B cell receptors. Protein A can form toxic immune complexes with IgG, thereby inducing leukocyte necrosis. Protein A contributes to the virulence expression of Staphylococcus aureus. Protein A triggers allergic reactions in IgG-pretreated mouse models. Protein A can be used in studies related to immune system diseases .

Narsoplimab 1 Publications Verification OMS 721; Anti-MASP2 Reference Antibody (narsoplimab)	SARS-CoV	Infection
Narsoplimab (OMS 721) is a high-affinity fully human immunoglobulin gamma 4 (IgG4) monoclonal antibody that binds MASP-2 and blocks lectin pathway activation. Narsoplimab can be used in research of hematopoietic stem-cell transplantation and SARS-CoV-2 .

Nesvacumab	Tie	Cardiovascular Disease Inflammation/Immunology Cancer
Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1. Nesvacumab can be used in vascular researches .

Vibostolimab	Transmembrane Glycoprotein	Cancer
Vibostolimab is an anti-TIGIT (*T cell immunoglobulin* and ITIM domain**) monoclonal antibody. Vibostolimab shows antitumor activity, and can be used in non-small cell lung cancer (NSCLC) and melanoma research .

KF38789 2 Publications Verification	P-selectin	Inflammation/Immunology
KF38789 is a selective inhibitor of P-selectin-PSGL-1 binding. KF38789 inhibits the binding of U937 cells to immobilized P-selectin immunoglobulin G chimeric protein (P-selectin-Ig) with an IC₅₀ value of 1.97 μM .

Sugemalimab	PD-1/PD-L1	Cancer
Sugemalimab is a fully human, full length, anti-programmed death ligand 1 (PD-L1) immunoglobulin G4 (IgG4) monoclonal antibody (mAb). Sugemalimab shows anticancer activities and can be used for non-small cell lung cancer research .

Etentamig ABBV-383; TNB 383B	CD3	Cardiovascular Disease Inflammation/Immunology Cancer
Etentamig is a BCMA × CD3 bispecific T-cell engager (BiTE) that can inhibit the activity of B-cell maturation antigen (BCMA) and activate the T-cell surface glycoprotein CD3 complex. Etentamig can be used for research in multiple myeloma, immunoglobulin light chain amyloidosis, and cardiovascular diseases .

Efbemalenograstim alfa Benegrastim; Bineuta; F 627	STAT	Inflammation/Immunology
Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells .

*Mouse immunoglobulin* G** Mouse IgG	Biochemical Assay Reagents	Inflammation/Immunology
Mouse Immunoglobulin G (Mouse IgG) is a mouse serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

Lenvervimab GC1102	HBV	Infection
Lenvervimab (GC1102) is a IgG1-type recombinant human hepatitis B Immunoglobulin. Lenvervimab can be used for research of hepatitis B virus infection .

Dilpacimab ABT165; PR1283233	VEGFR Notch	Cancer
Dilpacimab (ABT165) is a bispecific variable domain immunoglobulin. Dilpacimab binds to and inhibits DLL4 and VEGF and acts as a tumor growth inhibitor. Dilpacimab can be used in research related to metastatic colorectal cancer and advanced solid tumors .

Remtolumab ABT-122	TNF Receptor Interleukin Related	Inflammation/Immunology
Remtolumab is a bispecific variable domain immunoglobulin molecule with human affinities for TNFα and IL-17 in the low pM range of K_d. Remtolumab can be used in research related to rheumatoid arthritis, psoriatic arthritis, and moderate-to-severe plaque psoriasis .

Laflunimus HR325	Dihydroorotate Dehydrogenase DNA/RNA Synthesis Prostaglandin Receptor	Inflammation/Immunology
Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC₅₀ values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor .

Himic anhydride	Drug Derivative	Inflammation/Immunology
Himic anhydride is an acid anhydride compound and sensitizer. Himic anhydride with cross-reactivity to hexahydrophthalic anhydride. Himic anhydride induces immunoglobulin E (IgE)-mediated sensitization and allergic immune responses. Himic anhydride can be used for the research of occupational asthma .

Belrestotug EOS-448; EOS884448; GSK4428859A	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Belrestotug (EOS-448) is an antagonistic anti-TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity. Belrestotug can be used for cancer and immunological research such as colon cancer .

Calpurbatug TRL1068	Bacterial	Others
Calpurbatug is an immunoglobulin G1 antibody. Calpurbatug has activity with anti-bacterial DNA-binding protein DNABII family and anti-human monoclonal TRL1068 γ1-chain .

Pucotenlimab HX008	PD-1/PD-L1	Cancer
Pucotenlimab (HX008) is a humanized immunoglobulin G4 (IgG4) anti programmed cell death protein 1 (anti-PD-1) monoclonal antibody. Pucotenlimab can be used for the research of tumor .

Tosatoxumab KBSA301; AR-301	Antibiotic Bacterial	Infection
Tosatoxumab (AR-301; KBSA301) is a human immunoglobulin G1 monoclonal antibody that specifically neutralizes alpha-toxin (alpha-hemolysin; Hla) of S. aureus. Tosatoxumab binds to an N-terminal epitope of alpha-toxin, thereby preventing functional toxin pore oligomerisation. Tosatoxumab has the potential for passive immunotherapy in the S. aureus pneumonia as an adjunctive therapy to standard antibiotic agent. Recommend Isotope Control: Human IgG1 lambda1, Isotype Control (HY-P99992) .

*Dog Immunoglobulin* G** Dog IgG		Inflammation/Immunology
Dog Immunoglobulin G (Dog IgG) is a dog serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

Patecibart Getagozumab; GMA-301	Endothelin Receptor	Cardiovascular Disease
Patecibart is a humanized immunoglobulin G4-kappa, anti-EDNRA monoclonal antibody. Patecibart is an endothelin receptor antagonist .

Rolistobart	LILRB Transmembrane Glycoprotein	Cancer
Rolistobart is a humanized immunoglobulin G4-kappa, anti-LILRB4/CD85k monoclonal antibody. Rolistobart is an immunostimulant and antineoplastic .

Firsekibart Genakumab; GenSci048; Kinnazumab	Interleukin Related	Inflammation/Immunology
Firsekibart is an immunoglobulin G4-λ2 monoclonal antibody targeting human interleukin 1β (IL-1β). Firsekibart is promising for research of inflammation-related diseases, such as rheumatoid arthritis and inflammatory bowel disease .

Muzastotug ADG126	CTLA-4	Cancer
Muzastotug is a humanized immunoglobulin G1-kappa, anti-CTLA4 monoclonal antibody. Muzastotug is an immunostimulant and antineoplastic .

*Sheep immunoglobulin* G** Sheep IgG		Inflammation/Immunology
Sheep Immunoglobulin G (Sheep IgG) is a sheep serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

*Rabbit Immunoglobulin* G** Rabbit IgG	Biochemical Assay Reagents	Inflammation/Immunology
Rabbit Immunoglobulin G (Rabbit IgG) is a rabbit serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

Trinbelimab r-anti-D	Biochemical Assay Reagents	Others
Trinbelimab (r-anti-D) is a recombinant anti-D immunoglobulin that targets the RhD antigen. Trinbelimab exerts immunosuppressive effects to block maternal-fetal RhD alloimmunization. Trinbelimab can be used for the study of maternal-fetal immunity associated with RhD incompatibility .

Obertamig	CD3	Inflammation/Immunology
Obertamig is an engineered, humanized, anti-CD3E/HLA-G monoclonal antibody with humanized CH2-CH3 modifications and consists of half immunoglobulin IgG1 λ2 and a single-chain variable fragment (scFv) .

Cirevetmab ZTS-00521426	TGF-beta/Smad	Inflammation/Immunology
Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris TGFB1 caninized monoclonal antibody. Cirevetmab is an immunomodulator .

Jacalin	Biochemical Assay Reagents	Inflammation/Immunology
Jacalin is a lectin, that can be extracted from jackfruit seeds. Jacalin interacts with human immunoglobulins and lymphocytes, and can be used in immunology research .

Rat IgG Fc fragment	Fc Receptor (FcR)	Inflammation/Immunology
Rat IgG Fc fragment is a crystallizable fragment (Fc) of rat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.

Nelvutamig	Phosphodiesterase (PDE) CD3	Cancer
Nelvutamig is a humanized immunoglobulin (H-gamma1_L-kappa)_scFvkh-G1(h-CH2-CH3) antibody targeting ENPP3/CD203c and CD3E. The corresponding isotype control is: Human immunoglobulin (H-gamma1_L-kappa)_scFvkh-G1(h-CH2-CH3) .

Efpixileukin alfa XENP-27564; XMAB-27564	Interleukin Related	Inflammation/Immunology
Efpixileukin alfa is a fusion protein that combines human IL-2 variant fused at the C-terminus to human immunoglobulin G1 (IgG1) Fc fragment. Efpixileukin alfa is an immunomodulator .

Renvistobart BMS-986207; ONO-4686	CD28	Inflammation/Immunology
Renvistobart is an immunoglobulin G1-κ, anti-[Homo sapiens TIGIT (T cell immunoreceptor with Ig domain and ITIM, VSIG9, VSTM3)] Homo sapiens monoclonal antibody .

Clenoliximab IDEC-151	HIV	Inflammation/Immunology
Clenoliximab (IDEC-151) is a macaque-human chimeric monoclonal antibody (immunoglobulin G4) specific for the CD4 molecule on the surface of T lymphocytes. Clenoliximab can be used for the research of rheumatoid arthritis .

Ompekimig	Interleukin Related	Inflammation/Immunology
Ompekimig is a humanized immunoglobulin monoclonal antibody targeting human interleukin 4 (IL-4) and interleukin 13 (IL-13). Ompekimig is promising for research of immune-mediated inflammatory diseases, such as asthma and atopic dermatitis .

Lesabelimab LDP	PD-1/PD-L1	Inflammation/Immunology Cancer
Lesabelimab (LDP) is an immunoglobulin G1-kappa anti-CD274 monoclonal antibody. CD274 is an immune checkpoint ligand, represses antitumour immunity through the interaction with PDCD1 receptor .

Cat. No.	Product Name

HY-L127

Anti-Orthopoxvirus Compound Library

37 compounds

Orthopoxvirus is a genus of viruses in the family Poxviridae and subfamily Chordopoxvirinae. The orthopoxvirus genus consists of 12 viruses including variola virus, vaccinia virus (VV), cowpox viruses (CV), monkeypox virus, and camelpox virus. Smallpox has been eradicated worldwide in 1980, but some other orthopoxvirus, such as monkeypox virus, are still threats to human health.

There are not many drugs available for orthopoxvirus treatment. The only product currently available for treatment of complications of Orthopoxvirus infection is vaccinia immunoglobulin (VIG). In 2021, brincidofovir was approved by FDA for the treatment of smallpox and tecovirimat was approved by EMA for the treatment of monkeypox in 2022. A few active compounds including interferon and interferon inducers, and a variety of nucleosides or nucleotides have been reported to have activity against orthopoxvirus.

MCE carefully prepared a unique collection of 37 compounds reported with the anti- orthopoxvirus activity which can be used for drug screening and other research about orthopoxvirus.

Cat. No.	Product Name	Type

HY-D0025

7-Amino-4-methylcoumarin-3-acetic acid	Fluorescent Dyes
7-Amino-4-methylcoumarin-3-acetic acid (AMCA) serves as the parent structure of coumarin-based blue fluorescent dyes, and its activated form AMCA-NHS can directly conjugate with proteins (Ex/Em ≈ 350/440-460).

Cat. No.	Product Name	Type

HY-NP006

Protein A

1 Publications Verification

SPA

Biochemical Assay Reagents

Protein A (SPA) is an immunoglobulin (Ig)-binding protein that exists on the bacterial surface and can be freely secreted into the extracellular environment. Protein A blocks opsonophagocytosis and induces B cell apoptosis in vitro by binding to the Fc region of antibodies and the Fab region of B cell receptors. Protein A can form toxic immune complexes with IgG, thereby inducing leukocyte necrosis. Protein A contributes to the virulence expression of Staphylococcus aureus. Protein A triggers allergic reactions in IgG-pretreated mouse models. Protein A can be used in studies related to immune system diseases .

HY-NP0196

*Mouse immunoglobulin* G** Mouse IgG	Biochemical Assay Reagents
Mouse Immunoglobulin G (Mouse IgG) is a mouse serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-D0862

DIDNTB	Biochemical Assay Reagents
DIDNTB is a dye. DIDNTB exhibits chemical sensitivity and specificity toward albumin. DIDNTB is much less affected by other proteins. DIDNTB enables the detection of urinary albumin at concentrations ≥10 mg/L .\n

HY-NP0200

*Dog Immunoglobulin* G** Dog IgG	Biochemical Assay Reagents
Dog Immunoglobulin G (Dog IgG) is a dog serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-W145481A

D-Galacto-D-mannan

Carob galactomannan

Biochemical Assay Reagents

D-Galacto-D-mannan (Carob galactomannan) is an orally active Dectin-2 agonist. D-Galacto-D-mannan exerts antioxidant activity against hydroxyl radical generation. D-Galacto-D-mannan activates Dectin-2 to trigger downstream signaling pathways, promote the expression of immunoregulatory molecules, coordinate innate and adaptive immune responses, and inhibit excessive inflammatory responses by upregulating the expression of Sirtuin 1. When used as a vaccine adjuvant, D-Galacto-D-mannan induces cellular and humoral immune responses, promotes IFNγ secretion, increases antibody levels and virus neutralization titers, and elevates the levels of immunoglobulin G and A. D-Galacto-D-mannan can serve as an adjuvant for foot-and-mouth disease vaccines, enhance the vaccine-mediated ability of hosts to defend against viral infection in mice, and reduce local side effects at the inoculation site in pigs. D-Galacto-D-mannan can be used in the research of inflammatory and immune diseases, such as foot-and-mouth disease .

HY-NP0195

*Sheep immunoglobulin* G** Sheep IgG	Biochemical Assay Reagents
Sheep Immunoglobulin G (Sheep IgG) is a sheep serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-NP0198

*Rabbit Immunoglobulin* G** Rabbit IgG	Biochemical Assay Reagents
Rabbit Immunoglobulin G (Rabbit IgG) is a rabbit serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-NP086

Jacalin	Biochemical Assay Reagents
Jacalin is a lectin, that can be extracted from jackfruit seeds. Jacalin interacts with human immunoglobulins and lymphocytes, and can be used in immunology research .

HY-NP193A

Rat IgG Fc fragment	Biochemical Assay Reagents
Rat IgG Fc fragment is a crystallizable fragment (Fc) of rat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.

HY-NP0197A

Goat IgG Fc fragment	Biochemical Assay Reagents
Goat IgG Fc fragment is a crystallizable fragment (Fc) of goat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.

HY-NP0220

Chicken Yolk Immunoglobulin	Biochemical Assay Reagents
Chicken Yolk Immunoglobulin (IgY) is a natural antibody extracted from the yolk of immune hens. It has high stability and is widely used in antiviral, immunoassay and other fields .

HY-NP0212

*Bovine Immunoglobulin* G**	Biochemical Assay Reagents
Bovine Immunoglobulin G is a bovine serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-NP0196B

*Mouse Immunoglobulin* G2a**	Biochemical Assay Reagents
Mouse Immunoglobulin G2a is a mouse serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-NP0196C

*Mouse Immunoglobulin* G2b**	Biochemical Assay Reagents
Mouse Immunoglobulin G2b is a mouse serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-NP193

*Rat Immunoglobulin* G** Rat IgG	Biochemical Assay Reagents
Rat Immunoglobulin G (Rat IgG) is a rat serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-NP0197

*Goat immunoglobulin* G** Goat IgG	Biochemical Assay Reagents
Goat Immunoglobulin G (Goat IgG) is a goat serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-NP0196D

Mouse IgG Fc fragment	Biochemical Assay Reagents
Mouse IgG Fc fragment is a crystallizable fragment (Fc) of mouse immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.

HY-NP0198B

Rabbit IgG Fab fragment	Biochemical Assay Reagents
Rabbit IgG Fab fragment is a fragment of antigen (Fab) of rabbit immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.

HY-NP0198A

Rabbit IgG Fc fragment	Biochemical Assay Reagents
Rabbit IgG Fc fragment is a crystallizable fragment (Fc) of rabbit immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.

HY-NP0196E

Mouse IgG Fab fragment	Biochemical Assay Reagents
Mouse IgG Fab fragment is a fragment of antigen (Fab) of mouse immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.

HY-NP0217

*Horse Immunoglobulin* G**	Biochemical Assay Reagents
Horse Immunoglobulin G is a horse serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-NP0196A

*Mouse Immunoglobulin* G1**	Biochemical Assay Reagents
Mouse Immunoglobulin G1 is a mouse serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-NP0199

*Porcine Immunoglobulin* G** Porcine IgG	Biochemical Assay Reagents
Porcine Immunoglobulin G (Porcine IgG) is a porcine serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-NP0216

*Guinea pig Immunoglobulin* G**	Biochemical Assay Reagents
Guinea pig Immunoglobulin G is a guinea pig serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .

HY-NP193B

Rat IgG Fab fragment	Biochemical Assay Reagents
Rat IgG Fab fragment is a fragment of antigen (Fab) of rat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.

HY-NP0197B

Goat IgG Fab fragment	Biochemical Assay Reagents
Goat IgG Fab fragment is a fragment of antigen (Fab) of goat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.

Cat. No.	Product Name	Target	Research Area

HY-P0064

Palmitoyl Tetrapeptide-3 Palmitoyl Tetrapeptide-7	Interleukin Related	Inflammation/Immunology
Palmitoyl Tetrapeptide-3 (Palmitoyl Tetrapeptide-7) is a synthetic peptide corresponding to amino acids 341-344 of the human immunoglobulin heavy chain, with the ability to stimulate phagocytosis. Palmitoyl tetrapeptide-3 reduces interleukin-6 (IL-6) secretion in keratinocytes and inhibits the UVB radiation-exposure inflammatory response of skin. Palmitoyl tetrapeptide-3 It also has anti-inflammatory and anti-aging effects, reducing skin wrinkles by promoting the production of elastic fibers in the papillary dermis .

HY-P5309

IgA1 Peptide GN5	Biochemical Assay Reagents	Inflammation/Immunology
IgA1 Peptide GN5 is a synthetic glycopeptide and can be used for detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients .

HY-P60128

TTP	Peptides	Others
TTP is a generic surrogate peptide. TTP can be used for quantitative analysis of a recombinanthuman immunoglobulin G1 (hIgG1) in rat serum .

HY-P5309A

IgA1 Peptide GN5 TFA	Biochemical Assay Reagents	Inflammation/Immunology
IgA1 Peptide GN5 (TFA) is a synthetic glycopeptide and can be used for detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients .

HY-P0071

F 991	TNF Receptor Interleukin Related	Inflammation/Immunology
F 991 is an immunoglobulin free light chain antagonist. F 991 can significantly reduce the levels of pro-inflammatory cytokines (TNF-α and IL-6). F 991 can be used for research on allergic conditions .

HY-P10492

Tregitope 289	Peptides	Others Metabolic Disease
Tregitope 289 is a peptide derived from the Fc region of immunoglobulin G (IgG) and is a highly conserved T cell epitope that stimulates the expansion of natural regulatory T cells. Co-delivery of Tregitope 289 with type 1 diabetes (T1D) antigens delays the development of hyperglycemia and reduces the incidence of diabetes in the NOD mouse model. Tregitope 289 can be used to study T1D and other autoimmune diseases .

Cat. No.	Product Name

HY-K0230

Protein A/G Agarose 25+ Cited Publications
MCE Protein A/G Agarose is an affinity chromatography medium for separation and purification of immunoglobulins.

Cat. No.	Product Name	Target	Research Area	Image

HY-P99367

Ifinatamab DS-7300a Antibody; MABX-9001A Antibody	CD276/B7-H3	Inflammation/Immunology Cancer
Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur .

HY-P99955

Rocatinlimab AMG 451; KHK4083	Orexin Receptor (OX Receptor)	Infection Inflammation/Immunology
Rocatinlimab (AMG 451) (KHK4083) is a fully human immunoglobulin G1 (IgG1) anti-OX40 monoclonal antibody. Rocatinlimab can be used for the research of atopic dermatitis (AD) .

HY-P99033

Mosunetuzumab 1 Publications Verification BTCT-4465A; RG-7828; RO7030816	CD20 CD3	Inflammation/Immunology Cancer
Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs) .

HY-P99156

Relatlimab 3 Publications Verification BMS-986016	LAG-3	Cancer
Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC₅₀ value of 0.67 nM and LAG-3/FGL1 interaction with an IC₅₀ value of 0.019 nM. Relatlimab can be used in research of cancer .

HY-P990679

Rat IgG2a kappa, Isotype Control 3 Publications Verification	Inhibitory Antibodies	Inflammation/Immunology Cancer
Rat IgG2a kappa, Isotype Control is a monoclonal antibody derived from rats, representing the immunoglobulin G2a (IgG2a) subclass with a kappa light chain. Rat IgG2a kappa, Isotype Control exhibits high efficiency in inducing K cell mediated cytotoxicity. Rat IgG2a kappa, Isotype Control is utilized in research investigating the roles of different immunoglobulin subclasses in tumor immunology. Rat IgG2a kappa, an isotype control, can be used as an isotype control for Anti-Mouse PD-1 Antibody (RMP1-14) (HY-P99144), Anti-Mouse CD11a/LFA-1α Antibody (M17/4) (HY-P990801), and Anti-Mouse IL-2 Antibody (S4B6-1) (HY-P990796) .

HY-P9950

Omalizumab 1 Publications Verification Olizumab; rhuMab-E25; IGE25; RG-3648	Interleukin Related	Inflammation/Immunology Cancer
Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a K_D of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a K_D of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research . The component ratio of this product is Active ingredient : Excipients = 1:1.3-1:1.5.

HY-P99901

Sibeprenlimab VIS649	SARS-CoV	Inflammation/Immunology Cancer
Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody which inhibits a proliferation-inducing ligand (APRIL). Sibeprenlimab suppresses pathogenic immunoglobulins (IgA and IgM), while preserving antibody responses to mRNA-based vaccines against SARS-COV-2. Sibeprenlimab reduces urinary protein-to-creatinine ratio (UPCR) and glomerular filtration rate (GFR). Sibeprenlimab is promising for the research of IgA nephropathy (IgAN) .

HY-147305

Efgartigimod alfa ARGX-113	Fc Receptor (FcR)	Inflammation/Immunology
Efgartigimod alfa (ARGX-113) is a reversibility, humanized ^Fc receptor antagonist . Efgartigimod alfa is a anti FcRn monoclonal immunoglobulin G (IgG1) Fc fragment. Efgartigimod reduces serum levels of total IgG, including pathogenic autoantibodies, by blocking FcRn function without permanent impairment. Efgartigimod alfa can be used for generalised myasthenia gravis (gMG) and primary immune thrombocytopenia research .

HY-P9920A

Ramucirumab (anti-VEGFR) 1 Publications Verification	VEGFR	Cancer
Ramucirumab (anti-VEGFR) is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab (anti-VEGFR) is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D. Ramucirumab (anti-VEGFR) is also an angiogenesis inhibitor .

HY-P990706

Povetacicept ALPN-303	TNF Receptor	Inflammation/Immunology
Povetacicept (ALPN-303) is an engineered Fc fusion protein containing the TACI domain, and acts as a dual APRIL/BAFF antagonist. The K_d value of Povetacicept for human BAFF is 59.3 pM, while its K_d value for human APRIL is 1.00 pM. Povetacicept reduces the activation, proliferation, differentiation and survival of B cells, and inhibits the production of immunoglobulins and autoantibodies. Povetacicept can be used in research related to autoimmune hemolytic anemia, immune thrombocytopenia, systemic lupus erythematosus, lupus nephritis and myasthenia gravis .

HY-P9986

Tiragolumab MTIG-7192A; RG-6058	CD28	Cancer
Tiragolumab is an immune checkpoint inhibitor binding to the T-cell immunoglobulin and ITIM domain (TIGIT). Tiragolumab in combination with Atezolizumab (HY-P9904) and Bevacizumab (HY-P9906) has benefit in unresectable hepatocellular carcinoma. Tiragolumab can be used to study non-small cell lung cancer (NSCLC) and melanoma .

HY-P99550

Tozorakimab 1 Publications Verification MEDI-3506	Interleukin Related	Inflammation/Immunology
Tozorakimab (MEDI-3506) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. Tozorakimab reduces inflammation and epithelial dysfunction. Tozorakimab can be used to research chronic obstructive pulmonary disease .

HY-P99521

Vibecotamab XmAb14045	CD3	Inflammation/Immunology Cancer
Vibecotamab (XmAb14045) is a potent bispecific antibody targeting both CD123 and CD3. Vibecotamab targets T cell-mediated killing of CD123-expressing cells, regardless of T cell antigen specificity. Vibecotamab is a full length immunoglobulin molecule. Vibecotamab can be studied in research for diseases such as Myelodysplastic syndrome and acute myeloid leukemia. Recommend Isotype Control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3 .

HY-P99721

Lutikizumab ABT-981	Interleukin Related	Inflammation/Immunology
Lutikizumab (ABT-981) is an anti-IL-1α and IL-1β dual variable domain immunoglobulin. Lutikizumab binds and inhibits IL-1α and IL-1β. Lutikizumab can be used for the research of osteoarthritis .

HY-P990047

Maridebart AMG133 antibody	ADC Antibody GLP Receptor	Metabolic Disease
Maridebart (AMG133 antibody) is a human immunoglobulin G1-kappa, anti-GIPR (gastric inhibitory polypeptide receptor) monoclonal antibody. Maridebart is the antibody portion of Maridebart cafraglutide (HY-164535) and can be used for the synthesis of antibody-drug conjugates (ADC). Maridebart can be used for the reserrch of obesity and type 2 diabetes .

HY-P99376

Narsoplimab 1 Publications Verification OMS 721; Anti-MASP2 Reference Antibody (narsoplimab)	SARS-CoV	Infection
Narsoplimab (OMS 721) is a high-affinity fully human immunoglobulin gamma 4 (IgG4) monoclonal antibody that binds MASP-2 and blocks lectin pathway activation. Narsoplimab can be used in research of hematopoietic stem-cell transplantation and SARS-CoV-2 .

HY-P99300

Ligelizumab 1 Publications Verification QGE 031; Anti-IGHE Recombinant Antibody	Fc Receptor (FcR)	Inflammation/Immunology
Ligelizumab (QGE 031) is a humanized high-affinity anti-immunoglobulin IgE monoclonal antibody. Ligelizumab selectively inhibits the binding of IgE to the high-affinity receptor FcεRI, while the inhibitory effect on the low-affinity receptor CD23 is weak. Ligelizumab can inhibit the activation of effector cells such as mast cells and Basophil, while reducing the production of IgE by B cells, and restoring the IFN-α production and regulatory T cell (Treg) induction function of plasmacytoid dendritic cells (pDC). Ligelizumab can be used in the study of allergic diseases (such as chronic spontaneous urticaria, allergic asthma) .

HY-P99036

Nesvacumab	Tie	Cardiovascular Disease Inflammation/Immunology Cancer
Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1. Nesvacumab can be used in vascular researches .

HY-P991636

AK006	Transmembrane Glycoprotein	Inflammation/Immunology
AK006 is a humanized IgG1 monoclonal antibody agonist targeting *Sialic acid-binding immunoglobulin-like lectin6 (Siglec-6)*. AK006 potently inhibits IgE-mediated human mast cell activation. AK006 can be used for inflammatory diseases like chronic urticaria (CU) and asthma research .

HY-P99665

Insulin efsitora alfa LY-3209590	Insulin Receptor	Metabolic Disease
Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa is a fusion protein composed of human IR agonists fused with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2) fragment, with a molecular weight of 64.1 kDa. Insulin efsitora alfa is well tolerated and has potential applications in diabetes .

HY-P99950

Evorpacept ALX148	CD47	Cancer
Evorpacept (ALX148) is a high-affinity CD47-blocking fusion protein with an inactive human immunoglobulin Fc region. Evorpacept binds to CD47, blocks the interaction of the CD47-SIRPα immune checkpoint, and inhibits the binding of wild-type SIRPα to CD47. Evorpacept is applicable to research related to acute myeloid leukemia .

HY-P99934

Eftozanermin alfa 1 Publications Verification ABBV-621	Apoptosis Caspase TNF Receptor	Cancer
Eftozanermin alfa (ABBV-621) is a tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa is a fusion protein consisting of a mutant immunoglobulin G1-Fc linked to 2 single-chain trimers of TRAIL. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors (DR4 receptor and DR5 receptor) with K_ds of 780 nM and 635 nM. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies .

HY-P99460

Bapotulimab BAY-1905254	Inhibitory Antibodies	Inflammation/Immunology Cancer
Bapotulimab (BAY-1905254) is a fully human IgG2 antibody targeting immunoglobulin-like domain containing receptor 2 (ILDR2). Bapotulimab has antitumor and immunosuppressive effects .

HY-P99202

Vibostolimab	Transmembrane Glycoprotein	Cancer
Vibostolimab is an anti-TIGIT (*T cell immunoglobulin* and ITIM domain**) monoclonal antibody. Vibostolimab shows antitumor activity, and can be used in non-small cell lung cancer (NSCLC) and melanoma research .

HY-P99114

Sugemalimab	PD-1/PD-L1	Cancer
Sugemalimab is a fully human, full length, anti-programmed death ligand 1 (PD-L1) immunoglobulin G4 (IgG4) monoclonal antibody (mAb). Sugemalimab shows anticancer activities and can be used for non-small cell lung cancer research .

HY-P99313

Quilizumab Anti-Human IGHE Recombinant Antibody	Apoptosis	Inflammation/Immunology
Quilizumab (Anti-Human IGHE Recombinant Antibody) is a humanized IgG1κ monoclonal antibody targeting immunoglobulin epsilon (also konwn as: IGHE, IgE). Quilizumab targets the M1-prime fragment of membrane-expressed IGHE/IgE, leading to IGHE/IgE switching and memory B cell depletion. Quilizumab has potential in asthma research .

HY-P990045

Lixudebart ALE.F02	Claudin	Endocrinology
Lixudebart (ALE.F02) is a humanized immunoglobulin G1-kappa, anti-CLDN1 monoclonal antibody. Lixudebart disrupts CLDN1 interactions with CD44 and MMP14, reduces renal macrophage infiltration, epithelial activation, and urinary albumin-to-creatinine ratio, and attenuates glomerulosclerosis. Lixudebart can be used for the research of focal segmental glomerulosclerosis .

HY-P99382

Vopratelimab JTX 2011; 37A10	Inhibitory Antibodies	Inflammation/Immunology Cancer
Vopratelimab (JTX-2011) is a humanized immunoglobulin G1-kappa agonist monoclonal antibody that pecifically binds to the Inducible CO-Stimulator of T cells (ICOS). Vopratelimab retains species cross-reactivity with affinities of 0.93 nM to hICOS, 0.46 nM to cynomolgus ICOS, 3.7 nM to rat ICOS, and 0.64 nM to mICOS. Vopratelimab has antitumor immune response .

HY-P990785

Etentamig ABBV-383; TNB 383B	CD3	Cardiovascular Disease Inflammation/Immunology Cancer
Etentamig is a BCMA × CD3 bispecific T-cell engager (BiTE) that can inhibit the activity of B-cell maturation antigen (BCMA) and activate the T-cell surface glycoprotein CD3 complex. Etentamig can be used for research in multiple myeloma, immunoglobulin light chain amyloidosis, and cardiovascular diseases .

HY-P99879

Efbemalenograstim alfa Benegrastim; Bineuta; F 627	STAT	Inflammation/Immunology
Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells .

HY-P99693

Lenvervimab GC1102	HBV	Infection
Lenvervimab (GC1102) is a IgG1-type recombinant human hepatitis B Immunoglobulin. Lenvervimab can be used for research of hepatitis B virus infection .

HY-P99852

Dilpacimab ABT165; PR1283233	VEGFR Notch	Cancer
Dilpacimab (ABT165) is a bispecific variable domain immunoglobulin. Dilpacimab binds to and inhibits DLL4 and VEGF and acts as a tumor growth inhibitor. Dilpacimab can be used in research related to metastatic colorectal cancer and advanced solid tumors .

HY-P99940

Remtolumab ABT-122	TNF Receptor Interleukin Related	Inflammation/Immunology
Remtolumab is a bispecific variable domain immunoglobulin molecule with human affinities for TNFα and IL-17 in the low pM range of K_d. Remtolumab can be used in research related to rheumatoid arthritis, psoriatic arthritis, and moderate-to-severe plaque psoriasis .

HY-P99429

Alefacept BG 9273; Human LFA 3IgG fusion protein; LFA 3TIP	Inhibitory Antibodies	Others
Alefacept (BG 9273) is a human lymphocyte function-associated antigen 3/immunoglobulin 1 fusion protein. Alefacept can be used for the research of chronic plaque psoriasis .

HY-P990032

Belrestotug EOS-448; EOS884448; GSK4428859A	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Belrestotug (EOS-448) is an antagonistic anti-TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity. Belrestotug can be used for cancer and immunological research such as colon cancer .

HY-P99962

Surzebiclimab BGB-A425	Mucin	Cancer
Surzebiclimab (BGB-A425) is a humanized IgG1-variant monoclonal antibody against *T-cell immunoglobulin* and mucin-domain containing-3 (TIM-3). Surzebiclimab binds to the extracellular domain of human Tim-3 with high affinity (K_D**=0.36 nM) and specificity. Surzebiclimab can be used in research of cancer .

HY-P990021

Calpurbatug TRL1068	Bacterial	Others
Calpurbatug is an immunoglobulin G1 antibody. Calpurbatug has activity with anti-bacterial DNA-binding protein DNABII family and anti-human monoclonal TRL1068 γ1-chain .

HY-P99938

Pucotenlimab HX008	PD-1/PD-L1	Cancer
Pucotenlimab (HX008) is a humanized immunoglobulin G4 (IgG4) anti programmed cell death protein 1 (anti-PD-1) monoclonal antibody. Pucotenlimab can be used for the research of tumor .

HY-P99551

Tosatoxumab KBSA301; AR-301	Antibiotic Bacterial	Infection
Tosatoxumab (AR-301; KBSA301) is a human immunoglobulin G1 monoclonal antibody that specifically neutralizes alpha-toxin (alpha-hemolysin; Hla) of S. aureus. Tosatoxumab binds to an N-terminal epitope of alpha-toxin, thereby preventing functional toxin pore oligomerisation. Tosatoxumab has the potential for passive immunotherapy in the S. aureus pneumonia as an adjunctive therapy to standard antibiotic agent. Recommend Isotope Control: Human IgG1 lambda1, Isotype Control (HY-P99992) .

HY-P990089

Patecibart Getagozumab; GMA-301	Endothelin Receptor	Cardiovascular Disease
Patecibart is a humanized immunoglobulin G4-kappa, anti-EDNRA monoclonal antibody. Patecibart is an endothelin receptor antagonist .

HY-P990092

Rolistobart	LILRB Transmembrane Glycoprotein	Cancer
Rolistobart is a humanized immunoglobulin G4-kappa, anti-LILRB4/CD85k monoclonal antibody. Rolistobart is an immunostimulant and antineoplastic .

HY-P991138

Firsekibart Genakumab; GenSci048; Kinnazumab	Interleukin Related	Inflammation/Immunology
Firsekibart is an immunoglobulin G4-λ2 monoclonal antibody targeting human interleukin 1β (IL-1β). Firsekibart is promising for research of inflammation-related diseases, such as rheumatoid arthritis and inflammatory bowel disease .

HY-P99932

Eftansomatropin alfa TJ-101; GX-H9; hGH-hyFc; HL-2356	Inhibitory Antibodies	Metabolic Disease
Eftansomatropin alfa (GX-H9) is a fusion protein composed of rhGH (growth hormone) and immunoglobulin fragments. In Eftansomatropin alfa, rhGH is fused to a hybrid Fc domain comprising sequences of both IgD and IgG4. Eftansomatropin alfa can be used for the study of growth hormone deficiency (GHD) .

HY-163480

PF-06835375	CXCR	Inflammation/Immunology
PF-06835375 is a selective, humanized CXCR5-targeting immunoglobulin G1 antibody. PF-06835375 depletes CXCR5-positive B cells, follicular helper T cells and circulating Tfh-like cells. PF-06835375 is applicable to research related to autoimmune diseases .

HY-P991040

hu14.18 (K322A) Gamsitabart; M3554 Antibody	Inhibitory Antibodies	Cancer
hu14.18 (K322A) is a humanized anti-disialoganglioside GD2 monoclonal antibody that contains fully human amino acid sequences for immunoglobulin G1 heavy and kappa light chains. hu14.18 (K322A) has antibody-dependent cellular cytotoxicity (ADCC). hu14.18 (K322A) can be used for the study of high-risk neuroblastoma .

HY-P991198

M6903	Tim3	Cancer
M6903 is a humanized monoclonal IgG2 antibody targeting T cell immunoglobulin and mucin domain-3 (TIM-3) (KD for human TIM-3 is 2.3 nM). M6903 binds to TIM-3, blocking the binding of TIM-3 to phosphatidylserine (PtdSer), carcinoembryonic antigen cell adhesion-related molecule 1 (CEACAM1), and galectin 9 (Gal-9), thus relieving TIM-3-mediated T cell inhibition and exerting the activities of activating antigen-specific T cells and enhancing anti-tumor immunity. M6903 is promising for research of cancers .

HY-P990048

Muzastotug ADG126	CTLA-4	Cancer
Muzastotug is a humanized immunoglobulin G1-kappa, anti-CTLA4 monoclonal antibody. Muzastotug is an immunostimulant and antineoplastic .

HY-P99545

Trinbelimab r-anti-D	Biochemical Assay Reagents	Others
Trinbelimab (r-anti-D) is a recombinant anti-D immunoglobulin that targets the RhD antigen. Trinbelimab exerts immunosuppressive effects to block maternal-fetal RhD alloimmunization. Trinbelimab can be used for the study of maternal-fetal immunity associated with RhD incompatibility .

HY-P991230

MK-4830	Inhibitory Antibodies	Cancer
MK-4830 is a fully humanized monoclonal antibody of the immunoglobulin G4 subclass that specifically binds to ILT4 and blocks its interaction with HLA-G and other ligands. MK-4830 inhibits tumor growth in humanized mouse cancer models .

HY-P990714

Obertamig	CD3	Inflammation/Immunology
Obertamig is an engineered, humanized, anti-CD3E/HLA-G monoclonal antibody with humanized CH2-CH3 modifications and consists of half immunoglobulin IgG1 λ2 and a single-chain variable fragment (scFv) .

Cat. No.	Product Name		Classification

HY-174736

Human CD70 mRNA		mRNA
Human CD70 mRNA encodes the human CD70 molecule (CD70) protein, a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. CD70 induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. It is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

HY-174546

Human PECAM1 mRNA		mRNA
Human PECAM1 mRNA encodes the human platelet and endothelial cell adhesion molecule 1 (PECAM1) protein, a member of the immunoglobulin superfamily. PECAM1 is likely involved in leukocyte migration, angiogenesis, and integrin activation.

HY-174644

Human IL11 mRNA		mRNA Interleukin & Receptors
Human IL11 mRNA encodes the human interleukin 11 (IL11) protein, a member of the gp130 family of cytokines. IL11 is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells.

HY-174738

Human CD40 mRNA		mRNA
Human CD40 mRNA encodes the human CD40 molecule (CD40) protein, a member of the TNF-receptor superfamily. CD40 is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.

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