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Ramucirumab (anti-VEGFR)

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Based on 1 publication(s) in Google Scholar

Ramucirumab (anti-VEGFR) is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab (anti-VEGFR) is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D. Ramucirumab (anti-VEGFR) is also an angiogenesis inhibitor.

For research use only. We do not sell to patients.

  • Purity: 99.9%
  • CAS No.: 947687-13-0
  • Molecular Weight:144.56 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ramucirumab (anti-VEGFR)
  • Experimental Validation Results for Ramucirumab (anti-VEGFR)
  • Experimental Validation Results for Ramucirumab (anti-VEGFR)
  • Ramucirumab (anti-VEGFR) Chemical Structure
    Ramucirumab (anti-VEGFR) Chemical Structure
CAS No.: 947687-13-0
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Ramucirumab (anti-VEGFR) Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow cytometry analysis of VEGFR2 overexpression HEK293 cells labelling VEGFR2 with Ramucirumab at 200 nM (Red). Goat anti human IgG Fc (Alexa Fluor488) was used as the secondary antibody at 1/1000 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).

  • 1/16

    Immobilized Human VEGFR2/KDR/CD309, Fc Tag can bind Ramucirumab (anti-VEGFR). The EC50for this effect is 16.83 ng/mL.

  • Ramucirumab (anti-VEGFR) Chemical Structure
    1/16
  • Ramucirumab (anti-VEGFR)
  • Flow cytometry analysis of VEGFR2 overexpression HEK293 cells labelling VEGFR2 with Ramucirumab at 200 nM (Red). Goat anti human IgG Fc (Alexa Fluor488) was used as the secondary antibody at 1/1000 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).
  • Immobilized Human VEGFR2/KDR/CD309, Fc Tag can bind Ramucirumab (anti-VEGFR). The EC50for this effect is 16.83 ng/mL.