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Bevacizumab (PBS) (Synonyms: Anti-Human VEGF, Humanized Antibody (PBS))

Cat. No.: HY-P9906A
Handling Instructions

Bevacizumab, as a humanized vascular endothelial growth factor (VEGF) antibody, is a highly effective monoclonal antibody. Bevacizumab can be used for the research of cancer.

For research use only. We do not sell to patients.

Bevacizumab (PBS) Chemical Structure

Bevacizumab (PBS) Chemical Structure

CAS No. : 216974-75-3

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Description

Bevacizumab, as a humanized vascular endothelial growth factor (VEGF) antibody, is a highly effective monoclonal antibody. Bevacizumab can be used for the research of cancer[1][2].

In Vitro

Bevacizumab-loaded hydrogel results in significant tumor reduction. Bevacizumab is taken up by other organs, including the heart, lung, and spleen. Bevacizumab accumulates higher within tumors via Bevacizumab-loaded hydrogel administration from 14 days onward as compared to the solution formulation. Bevacizumab (I.v.) solution, a typical drug clearance profile is observed where the antibody is cleared from the circulatory system with a half-life of ~4~5 days. The Bevacizumab-loaded hydrogel and the weekly administration of Bevacizumab solution inhibits tumor growth/metastasis in the peritoneal cavity, while one-time i.v. injection of Bevacizumab solution does not provide any therapeutic effect, leading to extensive tumor metastasis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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Bevacizumab (PBS)
Cat. No.:
HY-P9906A
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