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Adalimumab

(Synonyms: Anti-Human TNF-alpha, Human Antibody; ABBV-3373 Antibody)
20 Cited Publications
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Based on 20 publication(s) in Google Scholar

Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).

For research use only. We do not sell to patients.

  • Purity: 99.27%
  • CAS No.: 331731-18-1
  • Molecular Weight:145.43 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Adalimumab
  • Experimental Validation Results for Adalimumab
  • Experimental Validation Results for Adalimumab
  • Experimental Validation Results for Adalimumab
  • Experimental Validation Results for Adalimumab
  • Experimental Validation Results for Adalimumab
  • Experimental Validation Results for Adalimumab
  • Experimental Validation Results for Adalimumab
  • Experimental Validation Results for Adalimumab
  • Adalimumab Chemical Structure
    Adalimumab Chemical Structure
CAS No.: 331731-18-1
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Bio/Physico-chemical AssayRT-PCRELISACell Imaging/StainingFlow Cytometry
  • ELISA
  • Cell Imaging/Staining
  • Flow Cytometry
  • RT-PCR
  • Bio/Physico-chemical Assay

All TNF Receptor Isoforms

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Adalimumab on AHC2 biosensor, can bind TNF-alpha/TNFSF2 Protein, Human (177a.a, His, HY-P700291) with an affinity constant of 2.247E-10 M as determined in BLI assay.

  • 1/16

    Immobilized TNF-alpha/TNFSF2 Protein, Human (HY-P7058) can bind Adalimumab. The EC50 for this effect is 6.753 ng/mL.

  • 1/16

    Flow Cytometry analysis of THP-1 cells with Adalimumab (HY-P9908, red) with Adalimumab (anti-Cytokeratin 19) (HY-P9908). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Adalimumab purchased from MedChemExpress. Usage Cited in: Adv Mater. 2025 Dec 12:e13952. [Abstract]

    Customer Validation
     Inhibitory dose-response curves to determine the IC50 for Adalimumab (5-20 μg/mL; 72 h) on secretion of TNF-α in the established rheumatoid arthritis model.

  • 1/16

    Adalimumab purchased from MedChemExpress. Usage Cited in: Adv Mater. 2025 Dec 12:e13952. [Abstract]

    Customer Validation
     Analysis of the ROS levels in the synovium part and cartilage part treated with Methotrexate (MTX), Adalimumab (ADA; 5-20 μg/mL; 72 h), and the combination of MTX and ADA.

  • 1/16

    Adalimumab purchased from MedChemExpress. Usage Cited in: Adv Mater. 2025 Dec 12:e13952. [Abstract]

    Customer Validation
     Drug testing in the 3D coculture RA model with T and B cells. The expression of Ki 67 and TNF-α on T and B cells evaluated by flow cytometer. RA, M1 Mφ incorporated 3D model that cocultured with T and B cells. RA+MTX (2 μM), RA model treated with Methotrexate. RA+ADA (5 μg/mL), RA model treated with Adalimumab. RA+MTX+ADA, RA model treated with Methotrexate and Adalimumab.

  • 1/16

    Adalimumab purchased from MedChemExpress. Usage Cited in: J Clin Invest. 2025 Jan 16;135(2):e178198. [Abstract]

    Customer Validation
     Real-time PCR of gene expression in MFS patient-specific iPSC-derived VSMCs with conditional media treatment in the presence of Adalimumab (10 μg/mL; 24 h) or IgG.

  • 1/16

    Adalimumab purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2024 Dec;11(46):e2404559. [Abstract]

    Customer Validation
     The real-time assessment data of the affinity between TNF-α protein and Adalimumab (2.5-80 nM) detected by the FED-MSPR biosensor.

  • Adalimumab Chemical Structure
    1/16
  • Adalimumab
  • Loaded Adalimumab on AHC2 biosensor, can bind TNF-alpha/TNFSF2 Protein, Human (177a.a, His, HY-P700291) with an affinity constant of 2.247E-10 M as determined in BLI assay.
  • Immobilized TNF-alpha/TNFSF2 Protein, Human (HY-P7058) can bind Adalimumab. The EC50 for this effect is 6.753 ng/mL.
  • Flow Cytometry analysis of THP-1 cells with Adalimumab (HY-P9908, red) with Adalimumab (anti-Cytokeratin 19) (HY-P9908). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).