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Belrestotug

(Synonyms: EOS-448; EOS884448; GSK4428859A)
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Based on 1 Customer Validation

Belrestotug (EOS-448) is an antagonistic anti-TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity. Belrestotug can be used for cancer and immunological research such as colon cancer.

For research use only. We do not sell to patients.

  • Purity: 97%
  • CAS No.: 2574438-65-4
  • Molecular Weight:145.7 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Belrestotug
  • Experimental Validation Results for Belrestotug
  • Experimental Validation Results for Belrestotug
  • Belrestotug Chemical Structure
    Belrestotug Chemical Structure
CAS No.: 2574438-65-4
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Belrestotug Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Belrestotug on AHC2 biosensor, can bind TIGIT Protein, Human (120a.a, HEK293, His, HY-P70624) with an affinity constant of 6.401E-10 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 FaDu cells with Belrestotug (HY-P990032, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Belrestotug Chemical Structure
    1/16
  • Belrestotug
  • Loaded Belrestotug on AHC2 biosensor, can bind TIGIT Protein, Human (120a.a, HEK293, His, HY-P70624) with an affinity constant of 6.401E-10 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 FaDu cells with Belrestotug (HY-P990032, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).