2. Immunology/Inflammation
  3. Human leukocyte immunoglobulin (Ig)-like receptors (LILR)
  4. Ricefidase

Ricefidase (KJ-103) is a recombinant human immunoglobulin G-degrading enzyme. Ricefidase efficiently cleaves human IgG at the hinge region. Ricefidase rapidly reduces IgG levels. Ricefidase has low immunogenicity and clears AAV neutralizing antibodies. Ricefidase is applicable to research related to desensitization of all IgG subclasses and improvement of the suitability of AAV-based gene therapy.

For research use only. We do not sell to patients.

Ricefidase

Ricefidase Chemical Structure

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Ricefidase Related Antibodies

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Description

Ricefidase (KJ-103) is a recombinant human immunoglobulin G-degrading enzyme. Ricefidase efficiently cleaves human IgG at the hinge region. Ricefidase rapidly reduces IgG levels. Ricefidase has low immunogenicity and clears AAV neutralizing antibodies. Ricefidase is applicable to research related to desensitization of all IgG subclasses and improvement of the suitability of AAV-based gene therapy[1].

Species Reactivity

Human
Clinical Trial
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
SMILES

[Ricefidase]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ricefidase Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RicefidaseKJ-103KJ103KJ 103Human leukocyte immunoglobulin (Ig)-like receptors (LILR)Human leukocyte immunoglobulin (Ig)-like receptorsLILRImmunoglobulin-like transcriptILTLIRMIRCD85IgGhinge regionAAV-based gene therapyAAV2 neutralizing antibodyorgan transplantationanti-drug antibodiesF(ab')2Fc fragmentsserum IgGhuman immunoglobulin GInhibitorinhibitorinhibit

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Ricefidase
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