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Surzebiclimab

(Synonyms: BGB-A425)
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Based on 1 Customer Validation

Surzebiclimab (BGB-A425) is a humanized IgG1-variant monoclonal antibody against T-cell immunoglobulin and mucin-domain containing-3 (TIM-3). Surzebiclimab binds to the extracellular domain of human Tim-3 with high affinity (KD=0.36 nM) and specificity. Surzebiclimab can be used in research of cancer.

For research use only. We do not sell to patients.

  • Purity: 95.00%
  • CAS No.: 2342597-90-2
  • Molecular Weight:145.72 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Surzebiclimab
  • Experimental Validation Results for Surzebiclimab
  • Surzebiclimab Chemical Structure
    Surzebiclimab Chemical Structure
CAS No.: 2342597-90-2
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Surzebiclimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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100 mg

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow cytometric analysis of 1.5X106 MCF-7 cells with Surzebiclimab (HY-P99962, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.

  • Surzebiclimab Chemical Structure
    1/16
  • Surzebiclimab
  • Flow cytometric analysis of 1.5X106 MCF-7 cells with Surzebiclimab (HY-P99962, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.