2342597-90-2
Chemical Structure
Surzebiclimab
Synonym(s): BGB-A425
- CAS No.: 2342597-90-2
- Formula:N/A
- Molecular Weight:(145.72 kDa)
IUPAC Name: 1-((3R,10R,14aS)-11-chloro-9-fluoro-10-(2-fluoro-6-hydroxyphenyl)-3-methyl-1,3,4,13,14,14a-hexahydro-2H-pyrazino[1',2':5,6][1,5]oxazocino[4,3,2-de]quinazolin-2-yl)prop-2-en-1-one
SMILES: [Surzebiclimab]
Biological Activity: Surzebiclimab (BGB-A425) is a humanized IgG1-variant monoclonal antibody against T-cell immunoglobulin and mucin-domain containing-3 (TIM-3). Surzebiclimab binds to the extracellular domain of human Tim-3 with high affinity (KD=0.36 nM) and specificity. Surzebiclimab can be used in research of cancer[1].
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Surzebiclimab | 95.00% | Surzebiclimab (BGB-A425) is a humanized IgG1-variant monoclonal antibody against T-cell immunoglobulin and mucin-domain containing-3 (TIM-3). Surzebiclimab binds to the extracellular domain of human Tim-3 with high affinity (KD=0.36 nM) and specificity. Surzebiclimab can be used in research of cancer. | ||||||||||||||||||||
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Keywords
