Obertamig
Based on 1 Customer Validation
Obertamig is an engineered, humanized, anti-CD3E/HLA-G monoclonal antibody with humanized CH2-CH3 modifications and consists of half immunoglobulin IgG1 λ2 and a single-chain variable fragment (scFv).
For research use only. We do not sell to patients.
- Purity: 95.803%
- CAS No.: 2750126-32-8
- Molecular Weight:148.813 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG1 kappa
Human
CD3E & HLA-G
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG1-kappa
ELISA, FACS, Functional assay
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Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Obertamig. The EC50 for this effect is 475.8 ng/mL. -
Immobilized HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein, Human (HEK293, His-Avi, HY-P77690) can bind Obertamig. The EC50 for this effect is 299.9 ng/mL.
Chemical Information
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CAS No. 2750126-32-8
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Appearance Liquid
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Molecular Weight 148.813 kDa
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Color Colorless to light yellow
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (253 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Obertamig
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)