Remtolumab
Based on 1 Customer Validation
Remtolumab is a bispecific variable domain immunoglobulin molecule with human affinities for TNFα and IL-17 in the low pM range of Kd. Remtolumab can be used in research related to rheumatoid arthritis, psoriatic arthritis, and moderate-to-severe plaque psoriasis.
For research use only. We do not sell to patients.
- Purity: 99.24%
- CAS No.: 1791410-27-9
- Molecular Weight:198.31 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
[VH-VH'-H-Gamma1_VL-VL'-C-kappa]-dimer
Human
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IL-17A |
Remtolumab (ABT-122) is the lead dual variable domain immunoglobul (DVD-Ig™) candidate selected based on its superior affinity and potency targeting human TNF and human IL-17 relative to other top candidates[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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[VH-VH'-H-Gamma1_VL-VL'-C-kappa]-dimer
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 1791410-27-9
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Appearance Liquid
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Molecular Weight 198.31 kDa
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Color Colorless to light yellow
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SMILES
[Remtolumab]
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Synonyms
ABT-122
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (257 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)