1791410-27-9
Chemical Structure
Remtolumab
Synonym(s): ABT-122
- CAS No.: 1791410-27-9
- Formula:N/A
- Molecular Weight:(198.31 kDa)
IUPAC Name: 5-nitroquinoline-4-carboxylic acid
SMILES: [Remtolumab]
Biological Activity: Remtolumab is a bispecific variable domain immunoglobulin molecule with human affinities for TNFα and IL-17 in the low pM range of Kd. Remtolumab can be used in research related to rheumatoid arthritis, psoriatic arthritis, and moderate-to-severe plaque psoriasis[1][2].
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Remtolumab | 99.24% | Remtolumab is a bispecific variable domain immunoglobulin molecule with human affinities for TNFα and IL-17 in the low pM range of Kd. Remtolumab can be used in research related to rheumatoid arthritis, psoriatic arthritis, and moderate-to-severe plaque psoriasis. | ||||||||||||||||||||
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- [1]. C.-M. Hsieh, et al. FRI0303 Discovery and Characterization of Abt-122, an Anti-TNF/IL-17 Dvd-Ig™ Molecule as A Potential Therapeutic Candidate for Rheumatoid Arthritis. Annals of the Rheumatic Diseases. 2014;72(2).
- [2]. Havnaer A, et al. Systemic therapies in psoriasis: an update on newly approved and pipeline biologics and oral treatments. Cutis. 2019;104(2S):17-20. [Content Brief]
Keywords