2. Anti-infection
  3. SARS-CoV
  4. Narsoplimab

Narsoplimab  (Synonyms: OMS 721; Anti-MASP2 Reference Antibody (narsoplimab))

Cat. No.: HY-P99376 Purity: ≥95.0%
COA

Molarity Calculator

Narsoplimab (OMS 721) is a high-affinity fully human immunoglobulin gamma 4 (IgG4) monoclonal antibody that binds MASP-2 and blocks lectin pathway activation. Narsoplimab can be used in research of hematopoietic stem-cell transplantation and SARS-CoV-2.

For research use only. We do not sell to patients.

Narsoplimab Chemical Structure

Narsoplimab Chemical Structure

CAS No. : 2108782-45-0

Size Price Stock Quantity
1 mg USD 420 In-stock
5 mg USD 1090 In-stock
10 mg USD 1745 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Narsoplimab Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Narsoplimab (OMS 721) is a high-affinity fully human immunoglobulin gamma 4 (IgG4) monoclonal antibody that binds MASP-2 and blocks lectin pathway activation. Narsoplimab can be used in research of hematopoietic stem-cell transplantation and SARS-CoV-2[1].

In Vitro

Narsoplimab (100 nM; 3 h; Vero E6 cells and Vero E6 cells with SARS-CoV-2) inhibits the N protein potentiated MASP-2 deposition[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Narsoplimab Related Antibodies
In Vivo

Narsoplimab (10 mg/kg; i.v.; WT and Masp2-/- (KO) mice) decreases percentage of lymphocytes (Lym%) and increases percentage of neutrophils (Neu%)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: WT and Masp2-/- (KO) mice (C57BL/6N, female, 12-15 weeks old)[1]
Dosage: 10 mg/kg
Administration: Intravenous injection
Result: Decreased percentage of lymphocytes (Lym%) and an increased percentage of neutrophils (Neu%).
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Narsoplimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: ≥95.0%

COA (231 KB)

Handling Instructions (2659 KB)
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Narsoplimab Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Narsoplimab2108782-45-0OMS 721 Anti-MASP2 Reference Antibody (narsoplimab)OMS721OMS-721SARS-CoVSARS coronavirusmonoclonal antibodylectin pathwayhematopoietic stem-cell transplantationSARS-CoV-2N proteinVero E6Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Narsoplimab
Cat. No.:
HY-P99376
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.