Oloctinebart
Based on 1 Customer Validation
Oloctinebart is a humanized immunoglobulin G4-kappa, anti-LGALS3 monoclonal antibody. Oloctinebart is used for reduction of amyloid beta oligomers formation.
For research use only. We do not sell to patients.
- Purity: 98.00%
- CAS No.: 2669063-84-5
- Molecular Weight:144.876 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG4 kappa
Human
Galectin-3/LGALS3
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
AAH53667.1
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Human IgG4 kappa
ELISA, FACS, Functional assay
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Loaded Oloctinebart on AHC2 biosensor, can bind Galectin-3/LGALS3 Protein, Human (HEK293, His, HY-P70171) with an affinity constant of 5.984E-08 M as determined in BLI assay. -
Flow Cytometry analysis of Hela cells labelling LGALS3 (red) with Oloctinebart (anti-LGALS3) (HY-P990081). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG4 (S228P) kappa (HY-P99003). Black-Unlabelled control, cells without incubation with primary antibody.
Chemical Information
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CAS No. 2669063-84-5
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Appearance Liquid
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Molecular Weight 144.876 kDa
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Color Colorless to light yellow
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SMILES
[Oloctinebart]
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Synonyms
TB-006
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)