1. Immunology/Inflammation
  2. CD20 CD3
  3. Mosunetuzumab

Mosunetuzumab  (Synonyms: BTCT-4465A)

Cat. No.: HY-P99033 Purity: 99.05%
COA

Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs).

For research use only. We do not sell to patients.

Mosunetuzumab Chemical Structure

Mosunetuzumab Chemical Structure

CAS No. : 1905409-39-3

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5 mg USD 710 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs)[1][2].

In Vitro

Mosunetuzumab has two arms. One arm binds specifically to CD3 on T-cells and the other to CD20 present on normal and neoplastic B-cells. Simultaneous binding of both arms to their respective targets facilitates T-cell-mediated killing of CD20+ B-cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Mosunetuzumab]

Shipping

Shipping with dry ice.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Purity: 99.05%

References
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Mosunetuzumab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Mosunetuzumab
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