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Cat. No.: HY-P992113

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Evabosmig

(Synonyms: AGA2118)

Evabosmig (AGA2118) is a bispecific antibody targeting SOST/sclerostin and DKK-1. Evabosmig binds to both SOST and DKK-1 simultaneously, activates the Wnt/β-catenin signaling pathway, and thereby potently promotes osteogenesis. Evabosmig can be used for the study of osteoporosis.

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CAS No.: 3061142-96-6

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Evabosmig Chemical Structure

CAS No.: 3061142-96-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Isotype
- Species Reactivity
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Isotype

immunoglobulin (H-gamma4_L-kappa) (H-gamma4_L-kappa)

Species Reactivity

Human

Voir tous les produits spécifiques à Isoform Wnt :

Gene ID

50964 [NCBI] & 22943 [NCBI]

Accession

Q9BQB4 & O94907

Target

SOST/Sclerostin & DKK1

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

IgG4-kappa

Application

ELISA, FACS, Functional assay

Chemical Information

CAS No. 3061142-96-6
SMILES

[Evabosmig]
Synonyms

AGA2118
Formulation

Please refer to the lot-specific COA for specific buffer information.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Inhibitory Antibodies User Guide (603 KB)

Références

[1]. Drake, M. T., et al. (2024, September). AGA2118, a bispecific monoclonal antibody neutralizing both sclerostin and DKK1, increased bone Formation, decreased bone resorption, and led to rapid BMD gains in a first in human, single-and multiple-dose, placebo-controlled, randomized study. In ASBMR 2024 Annual Meeting. ASBMR.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- Isotype
- Species Reactivity
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Pureté et documentation
Références

Nom du produit:
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Quantité:
MCE Japan Authorized Agent:

Nom du produit:
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Evabosmig

PBS Buffer (1×)

DPBS Buffer (1×)

Cytotoxicity LDH Assay Kit

Voir tous les produits spécifiques à Isoform Wnt

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Evabosmig Related Classifications

HY-P992113 Related Classifications