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Evabosmig

(Synonyms: AGA2118)
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Based on 1 Customer Validation

Evabosmig (AGA2118) is a humanized bispecific monoclonal antibody targeting sclerostin (SOST/sclerostin) and DKK1. SOST and DKK1 are two key secreted negative regulators of the intramedullary Wnt/β-catenin pathway. Evabosmig possesses activities to induce bone formation, inhibit bone resorption and increase bone mineral density. Evabosmig is applicable for research related to osteoporosis.

For research use only. We do not sell to patients.

  • Purity: 97.91%
  • CAS No.: 3061142-96-6
  • Molecular Weight:145.18 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Evabosmig
  • Experimental Validation Results for Evabosmig
  • Experimental Validation Results for Evabosmig
  • Evabosmig Chemical Structure
    Evabosmig Chemical Structure
CAS No.: 3061142-96-6
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Evabosmig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

All Wnt Isoforms

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Assay Types
  • 1/16

    IgG4-kappa

  • 1/16

    Immobilized SOST Protein, Human (HEK293, HY-P70756) can bind Evabosmig. The ED50 for this effect is 361 ng/mL.

  • 1/16

    Loaded Evabosmig on biosensor, can bind DKK-1 Protein, Human (HEK293, HY-P7155A) with an affinity constant of 6.75E-10 M as determined in BLI assay.

  • Evabosmig Chemical Structure
    1/16
  • Evabosmig
  • Immobilized SOST Protein, Human (HEK293, HY-P70756) can bind Evabosmig. The ED50 for this effect is 361 ng/mL.
  • Loaded Evabosmig on biosensor, can bind DKK-1 Protein, Human (HEK293, HY-P7155A) with an affinity constant of 6.75E-10 M as determined in BLI assay.
  • IgG4-kappa