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Cat. No.: HY-W015405

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4-Methylphthalic anhydride

Name: 4-Methylphthalic anhydride
Brand: MedChemExpress
SKU: HY-W015405
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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4-Methylphthalic anhydride is an organic acid anhydride and an immunogen/sensitizer. 4-Methylphthalic anhydride induces the production of specific immunoglobulin E and immunoglobulin G antibodies. 4-Methylphthalic anhydride is used in studies of occupational allergy.

For research use only. We do not sell to patients.

CAS No.: 19438-61-0
Formula: C₉H₆O₃
Molecular Weight:162.14

Storage:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

4-Methylphthalic anhydride Chemical Structure

CAS No.: 19438-61-0

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

All Human leukocyte immunoglobulin (Ig)-like receptors (LILR) Isoforms :

LILRB

In Vitro

4-methylphthalic anhydride forms a conjugate with rat serum albumin at a hapten density of 26 mol/mol (UV method) and 27 mol/mol (TNBS method)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

In Vivo

4-Methylphthalic anhydride (0.1 mL of 0.2 M; intradermal; single injection split into two 0.05 mL portions) induces the highest median specific IgE (3200) and IgG (6400) titers in Brown Norway rats compared to other tested organic acid anhydrides via intradermal immunization^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Brown Norway (BN) (male, 100-150 g, acclimatized for 1 week before experimentation)^[1]
Dosage:

0.1 mL of 0.2 M
Administration:

intradermal; single injection split into two 0.05 mL portions
Result:

Exhibited the highest specific IgE and IgG titers among all tested organic acid anhydrides.
Reached a median specific IgE titer of 3200, with a range of 3200-6400.
Reached a median specific IgG titer of 6400, with a range of 3200-6400.
Showed titers significantly higher than those induced by all other tested organic acid anhydrides (P<0.05).

Chemical Information

CAS No. 19438-61-0
Appearance Solid
Molecular Weight 162.14
Formula C₉H₆O₃
SMILES

O=C1OC(=O)C2=CC(=CC=C12)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang XD, et al. Antibody responses of rats after immunization with organic acid anhydrides as a model of predictive testing. Scand J Work Environ Health. 1998;24(3):220-227. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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