4-Methylphthalic anhydride
Based on 1 Customer Validation
4-Methylphthalic anhydride is an organic acid anhydride and an immunogen/sensitizer. 4-Methylphthalic anhydride induces the production of specific immunoglobulin E and immunoglobulin G antibodies. 4-Methylphthalic anhydride is used in studies of occupational allergy.
For research use only. We do not sell to patients.
- CAS No.: 19438-61-0
- Formula: C9H6O3
- Molecular Weight:162.14
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
4-methylphthalic anhydride forms a conjugate with rat serum albumin at a hapten density of 26 mol/mol (UV method) and 27 mol/mol (TNBS method)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Brown Norway (BN) (male, 100-150 g, acclimatized for 1 week before experimentation)[1]
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Dosage:0.1 mL of 0.2 M
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Administration:intradermal; single injection split into two 0.05 mL portions
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Result:Exhibited the highest specific IgE and IgG titers among all tested organic acid anhydrides.
Reached a median specific IgE titer of 3200, with a range of 3200-6400.
Reached a median specific IgG titer of 6400, with a range of 3200-6400.
Showed titers significantly higher than those induced by all other tested organic acid anhydrides (P<0.05).
Chemical Information
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CAS No. 19438-61-0
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Appearance Solid
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Molecular Weight 162.14
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Formula C9H6O3
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SMILES
O=C1OC(=O)C2=CC(=CC=C12)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Methylphthalic anhydride Related Classifications
HY-W015405 Related Classifications
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