Search Result

Results for "

IGF

" in MedChemExpress (MCE) Product Catalog:

By Targets:	IGF-1R (45) ADC Antibody (1) Adenylate Cyclase (2) Akt (2) Anaplastic lymphoma kinase (ALK) (6) Apoptosis (15) Aurora Kinase (1) Autophagy (3) Bcr-Abl (1) Caspase (1) Cholinesterase (ChE) (1) COX (1) Drug Metabolite (4) EGFR (5) FAK (1) G-quadruplex (1) Glucosidase (1) Insulin Receptor (15) Isotope-Labeled Compounds (1) JNK (1) mTOR (1) NF-κB (1) PARP (1) Pyk2 (1) ROS Kinase (1) SARS-CoV (1) Small Interfering RNA (siRNA) (12) Somatostatin Receptor (5) Src (1) STAT (1) Telomerase (1) TSH Receptor (1) VEGFR (1)
By Research Areas:	Cancer (47) Cardiovascular Disease (3) Endocrinology (24) Infection (1) Inflammation/Immunology (7) Metabolic Disease (9) Neurological Disease (2)

By Targets:

IGF-1R (45)

ADC Antibody (1)

Adenylate Cyclase (2)

Akt (2)

Anaplastic lymphoma kinase (ALK) (6)

Apoptosis (15)

Aurora Kinase (1)

Autophagy (3)

Bcr-Abl (1)

Caspase (1)

Cholinesterase (ChE) (1)

COX (1)

Drug Metabolite (4)

EGFR (5)

FAK (1)

G-quadruplex (1)

Glucosidase (1)

Insulin Receptor (15)

Isotope-Labeled Compounds (1)

JNK (1)

mTOR (1)

NF-κB (1)

PARP (1)

Pyk2 (1)

ROS Kinase (1)

SARS-CoV (1)

Small Interfering RNA (siRNA) (12)

Somatostatin Receptor (5)

Src (1)

STAT (1)

Telomerase (1)

TSH Receptor (1)

VEGFR (1)

By Research Areas:

Cancer (47)

Cardiovascular Disease (3)

Endocrinology (24)

Infection (1)

Inflammation/Immunology (7)

Metabolic Disease (9)

Neurological Disease (2)

Inhibitors & Agonists

Screening Libraries

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

IGF-1R inhibitor-2	IGF-1R	Cancer
IGF-1R inhibitor-2 (example 121) is an insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis .

IGF-I (24-41) Insulin-like Growth Factor I (24-41)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development .

IGF2BP1-IN-1	Insulin Receptor	Cancer
IGF2BP1-IN-1 (Compound A11) is a *IGF2BP1* inhibitor and inhibits downstream signaling. IGF2BP1-IN-1 binds to IGF2BP1 protein with a K_D value of 2.88 nM. IGF2BP1-IN-1 inhibits cancer cells proliferation (IC₅₀: 9 nM for A549 cell, 34 nM for HCT116). IGF2BP1-IN-1 induces cancer cell apoptosis. GF2BP1-IN-1 inhibits tumor growth in A549 xenograft mouse model .

IGF1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IGF1 Human Pre-designed siRNA Set A contains three designed siRNAs for IGF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IGF2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IGF2 Human Pre-designed siRNA Set A contains three designed siRNAs for IGF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IGF-I (24-41) (TFA) Insulin-like Growth Factor I (24-41) (TFA)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development .

IGF1R Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IGF1R Human Pre-designed siRNA Set A contains three designed siRNAs for IGF1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Igf1r Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Igf1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Igf1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Igf1r Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Igf1r Rat Pre-designed siRNA Set A contains three designed siRNAs for Igf1r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

IGF2R Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IGF2R Human Pre-designed siRNA Set A contains three designed siRNAs for IGF2R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IGF2BP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IGF2BP1 Human Pre-designed siRNA Set A contains three designed siRNAs for IGF2BP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IGF2BP2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IGF2BP2 Human Pre-designed siRNA Set A contains three designed siRNAs for IGF2BP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IGF2BP3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IGF2BP3 Human Pre-designed siRNA Set A contains three designed siRNAs for IGF2BP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IGF-I (30-41) (TFA) Insulin-like Growth Factor I (30-41) (TFA)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .

Xentuzumab BI 836845; Anti-Human IGF1 and IGF2 Recombinant Antibody	IGF-1R	Cancer
Xentuzumab (Anti-Human IGF1 and IGF2 Recombinant Antibody; BI836845) is a recombinant a human monoclonal antibody that targets IGF ligands *IGF1* and *IGF2. Xentuzumab inhibits both of IGF1* and *IGF2* growth-promoting signalling and suppresses AKT activation .

NBI-31772 hydrate	IGF-1R	Neurological Disease
NBI-31772 hydrate is a potent inhibitor of interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). NBI-31772 hydrate is also a nonpeptide ligand that releases bioactive IGF-I from the IGF-I/IGFBP-3 complex (K_is=1-24 nM for all six human subtypes). Anxiolytic and antidepressant-like effects .

Ganitumab AMG 479; Human Anti-IGF1R Recombinant Antibody	IGF-1R	Cancer
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

AZD-3463 ALK/IGF1R inhibitor	IGF-1R Anaplastic lymphoma kinase (ALK) Autophagy Apoptosis	Endocrinology Cancer
AZD-3463 (ALK/IGF1R inhibitor) is an orally active *ALK/IGF1R* inhibitor, with a K_i of 0.75 nM for ALK. AZD3463 induces apoptosis and autophagy in neuroblastoma cells .

*INS-IGF2 Human Pre-designed siRNA Set A*	Small Interfering RNA (siRNA)	Others
INS-IGF2 Human Pre-designed siRNA Set A contains three designed siRNAs for INS-IGF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mecasermin Human IGF-I; FK 780	IGF-1R	Metabolic Disease
Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies .

Ginsenoside Rg5 1 Publications Verification	IGF-1R NF-κB COX	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Ginsenoside Rg5 is the main component of Red ginseng and *IGF-1R* agonist. Ginsenoside Rg5 compets for the binding site of IGF-1R and blocks the binding of *IGF-1* to IGF-1R (IC₅₀ about 90 nM). Ginsenoside Rg5 also inhibits the mRNA expression of COX-2 via suppression of the DNA binding activities of NF-κB p65.

Teprotumumab	IGF-1R TSH Receptor	Endocrinology
Teprotumumab is an **IGF-1 receptor (IGF-1R)** blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular α-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research .

Dalotuzumab MK-0646; h7C10	IGF-1R Apoptosis	Cancer
Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting *IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2*-mediated tumor cell proliferation, *IGF-1R* autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo .

AZ12253801	IGF-1R	Cancer
AZ12253801 is an ATP-competitive *IGF-1R* tyrosine kinase inhibitor that shows ∼10-fold selectivity over the insulin receptor. AZ12253801 inhibits IGF-1R–driven proliferation in 3T3 mouse fibroblasts (transfected with human IGF-1R) with an IC₅₀ of 17 nmol/L. The IC₅₀ for epidermal growth factor receptor (EGFR)–driven proliferation is 440 nmol/L. Anti-tumor activity.

Istiratumab MM 141; MM-005	IGF-1R EGFR	Cancer
Istiratumab (M-6495) is bispecific monoclonal antibody targeting *IGF-1R* and ErbB3. Istiratumab induces IGF-1R and ErbB3 receptor degradation through the proteasome pathway Istiratumab can be used for research of cancers .

AG 538	IGF-1R	Cancer
AG 538 is a potent, competitive inhibitor of IGF-1 receptor kinase, with an IC₅₀ of 400 nM .

PQ401 2 Publications Verification	IGF-1R Apoptosis	Cancer
PQ401 is a potent inhibitor of *IGF-IR* signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC₅₀ of 12.0 μM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC₅₀, 6 μM). PQ401 is a potential agent for breast and other IGF-I-sensitive cancers. PQ401 induces caspase-mediated apoptosis .

Dusigitumab MEDI 573	IGF-1R	Others
Dusigitumab (MEDI 573) is a human IgG2λ monoclonal antibody that specifically targets IGF2 and IGF1 .

Figitumumab CP-751871	IGF-1R	Cancer
Figitumumab (CP-751871) is a potent and fully human monoclonal anti–insulin-like growth factor 1 receptor (IGF1R) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC₅₀ of 1.8 nM .

Picropodophyllin 15+ Cited Publications AXL1717; Picropodophyllotoxin; PPP	IGF-1R Apoptosis	Endocrinology Cancer
Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC₅₀ of 1 nM.

Indirubin Derivative E804
Indirubin Derivative E804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor *(IGF1R), with an IC₅₀* of 0.65 μM for IGF1R.

Linsitinib Maximum Cited Publications 33 Publications Verification OSI-906	IGF-1R Insulin Receptor	Endocrinology Cancer
Linsitinib (OSI-906) is a potent, selective and orally bioavailable dual inhibitor of the IGF-1 receptor and insulin receptor (IR) with IC₅₀s of 35 and 75 nM, respectively .

Chromeceptin 94G6	IGF-1R Akt mTOR	Cancer
Chromeceptin (94G6) is an IGF signaling pathway inhibitor. Chromeceptin suppresses IGF2 expression at mRNA and protein levels in hepatocyte and HCC cells. Chromeceptin inhibits the phosphorylation levels of AKT and mTOR .

AVJ16	Insulin Receptor	Cancer
AVJ16 is a cancer cell migration inhibitor that targets the insulin-like growth factor 2 mRNA binding protein *IGF2BP1* to inhibit the migration of H1299 cells with high endogenous IGF2BP1 expression. AVJ16 interferes with IGF2BP1 binding target mRNA to regulate gene expression and translation .

XL228 3 Publications Verification	Aurora Kinase Bcr-Abl IGF-1R Src	Endocrinology Cancer
XL228 is a multi-targeted tyrosine kinase inhibitor with IC₅₀s of 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, *IGF-1R, Src* and Lyn, respectively.

I-OMe-Tyrphostin AG 538 I-OMe-AG 538	IGF-1R	Metabolic Disease Cancer
I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of *IGF-1R* (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells. I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα), with an IC₅₀ of 1 µM .

Picropodophyllin-d6 AXL1717-d₆; Picropodophyllotoxin-d₆; PPP-d₆	Isotope-Labeled Compounds IGF-1R Apoptosis	Endocrinology Cancer
Picropodophyllin-d₆ (AXL1717-d₆) is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.

CWI1-2 hydrochloride	Apoptosis	Cancer
CWI1-2 hydrochloride is an *IGF2BP2* inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects .

CWI1-2	Apoptosis	Cancer
CWI1-2 is an *IGF2BP2* inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects .

BMS-536924 3 Publications Verification	IGF-1R Insulin Receptor Apoptosis	Endocrinology Cancer
BMS-536924 is an orally active, competitive and selective insulin-like growth factor receptor (IGF-1R) kinase and insulin receptor (IR) inhibitor with IC₅₀s of 100 nM and 73 nM, respectively. BMS-536924 has anti-cancer activity .

AG1024 4 Publications Verification Tyrphostin AG 1024	IGF-1R Insulin Receptor Apoptosis	Endocrinology Cancer
AG1024 (Tyrphostin AG 1024) is a reversible, competitive and selective *IGF-1R* inhibitor with an IC₅₀ of 7 μM. AG1024 inhibits phosphorylation of IR (IC₅₀=57 μM). AG1024 induces apoptosis and has anti-cancer activity .

Robatumumab Sch 717454; 19D12	IGF-1R	Cancer
Robatumumab (Sch 717454) is an anti-human *IGF-1R* (insulin-like growth factor receptor-1) antibody. Robatumumab shows anti-tumor activity and anti-proliferative activity to cancer cells. Robatumumab can be used in osteosarcoma and Ewing sarcoma research .

Cimdelirsen sodium ISIS 766720 sodium; IONIS-GHR-LRx sodium	Small Interfering RNA (siRNA)	Others
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.

Cimdelirsen ISIS 766720; IONIS-GHR-LRx	Small Interfering RNA (siRNA)	Others
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.

Paltusotine 1 Publications Verification CRN00808	Somatostatin Receptor	Endocrinology Cancer
Paltusotine (CRN00808) is an orally active, nonpeptide selective somatostatin type 2 (SST2) receptor agonist. Paltusotine has the potential for maintaining GH and IGF-1 levels after depot somatostatin receptor ligand therapy.Paltusotine can be used in research on acromegaly and neuroendocrine tumors .

Voglibose	Glucosidase	Metabolic Disease
Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis.

Cat. No.	Product Name

HY-L034

Anti-Aging Compound Library

4352 compounds

Aging is a complex biological process characterized by functional decline of tissues and organs, structural degeneration, and reduced adaptability and resistance, all of which contribute to an increase in morbidity and mortality caused by multiple chronic diseases, such as Alzheimer's disease, cancer, and diabetes. Many theories, which fall into two main categories: programmed and error theories, have been proposed to explain the process of aging, but neither of them appears to be fully satisfactory. The programmed theories imply that aging relies on specific gene regulation, and the error theories emphasize the internal and environmental damages accumulated to living organisms. The damage theories proposed the nine hallmarks that were generally considered to contribute to the aging process: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication.

MCE Anti-Aging Compound Library contains 4352 compounds, mainly targeting Sirtuin, mTOR, IGF-1R, AMPK, p53, Telomerase, Mitophagy, Mitochondrial Metabolism, COX, Cytochrome P450, Oxidase, etc. This library is a useful tool for anti-aging research.

HY-L124

Anti-Prostate Cancer Compound Library

2295 compounds

Cancer is one of the leading causes of mortality amongst world’s population, in which prostate cancer (PCa) is one of the most encountered malignancies among men. Several molecular mechanisms are involved in prostate cancer development and progression. These include common survival factors in prostate cancer (IGF-1), growth factors (TGF-α, EGF), Wnt, Hedgehog, NF-κB, and mTOR and other signaling pathways. These provide potential therapeutic target in prostate cancer treatment.

MCE offers a unique collection of 2295 compounds with identified and potential anti-prostate cancer activity. MCE Anti-Prostate Cancer Compound Library is a useful tool for anti-prostate cancer drugs screening and other related research.

Cat. No.	Product Name	Target	Research Area

HY-P1777

IGF-I (24-41) Insulin-like Growth Factor I (24-41)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development .

HY-P10044

IGF1Rtide

Peptides Others

IGF1Rtide can be used as a RET kinase substrate for RET kinase assays .

HY-P1777A

IGF-I (24-41) (TFA) Insulin-like Growth Factor I (24-41) (TFA)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development .

HY-P1773

IGF-I (30-41) Insulin-like Growth Factor I (30-41)	Peptides	Metabolic Disease Inflammation/Immunology
IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .

HY-P1773A

IGF-I (30-41) (TFA) Insulin-like Growth Factor I (30-41) (TFA)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .

HY-108905

Mecasermin Human IGF-I; FK 780	IGF-1R	Metabolic Disease
Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies .

HY-P5438

Srctide	Peptides	Others
Srctide is a biological active peptide. (This is a peptide substrate for many protein kinases, such as Blk, BTK, cKit, EPHA1, EPHB2, EPHB3, ERBB4, FAK, Flt3, IGF-1R, ITK, Lck, MET, MUSK, Ret, Src, TIE2, TrkB, VEGF-R1 (Flt-1) and VEGF-R2 (KDR).)

HY-P5527F

FAM-CSKtide	Peptides	Others
FAM-CSKtide is a biological active peptide. (This is a FAM labeled peptide substrate (Abs/Em = 494/521 nm) for C-terminal Src kinase (Csk) and many other kinases such as Axl, cKit, ERBB4, Fes, Flt3, IGF-1 R, MET, MUSK, PYK2, Ret, TIE2, TrkA, VEGF-R1 and VEGF-R2.)

HY-P4813

Preptin (rat)

Peptides Metabolic Disease

Preptin, an osteogenic peptide product of the pancreatic beta-cell, corresponds to Asp ⁶⁹-Leu ¹⁰² of pro-IGF-II .

HY-P2090

Angiopeptin	Somatostatin Receptor Adenylate Cyclase	Cardiovascular Disease
Angiopeptin, a cyclic octapeptide analogue of somatostatin, is a weak sst₂/sst₅ receptor partial agonist with IC₅₀ values of 0.26 nM and 6.92 nM, respectively. Angiopeptin is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin has the potential for coronary atherosclerosis research .

HY-P2090A

Angiopeptin TFA	Somatostatin Receptor Adenylate Cyclase	Cardiovascular Disease
Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weak sst₂/sst₅ receptor partial agonist with IC₅₀ values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin TFA inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin TFA has the potential for coronary atherosclerosis research .

HY-16381

Pasireotide SOM230	Somatostatin Receptor	Endocrinology Cancer
Pasireotide (SOM230), a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pK_i=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide also exhibits antisecretory, antiproliferative, and proapoptotic activity .

HY-16381A

Pasireotide acetate 1 Publications Verification SOM230 acetate	Somatostatin Receptor	Endocrinology Cancer
Pasireotide (SOM230) acetate, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pK_i=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide acetate can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide acetate also exhibits antisecretory, antiproliferative, and proapoptotic activity .

Cat. No.	Product Name	Target	Research Area

HY-P99274

Xentuzumab BI 836845; Anti-Human IGF1 and IGF2 Recombinant Antibody	IGF-1R	Cancer
Xentuzumab (Anti-Human IGF1 and IGF2 Recombinant Antibody; BI836845) is a recombinant a human monoclonal antibody that targets IGF ligands *IGF1* and *IGF2. Xentuzumab inhibits both of IGF1* and *IGF2* growth-promoting signalling and suppresses AKT activation .

HY-P99294

Ganitumab AMG 479; Human Anti-IGF1R Recombinant Antibody	IGF-1R	Cancer
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

HY-P99165

Teprotumumab	IGF-1R TSH Receptor	Endocrinology
Teprotumumab is an **IGF-1 receptor (IGF-1R)** blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular α-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research .

HY-P99284

Dalotuzumab MK-0646; h7C10	IGF-1R Apoptosis	Cancer
Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting *IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2*-mediated tumor cell proliferation, *IGF-1R* autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo .

HY-P99672

Istiratumab MM 141; MM-005	IGF-1R EGFR	Cancer
Istiratumab (M-6495) is bispecific monoclonal antibody targeting *IGF-1R* and ErbB3. Istiratumab induces IGF-1R and ErbB3 receptor degradation through the proteasome pathway Istiratumab can be used for research of cancers .

HY-P99867

Dusigitumab

MEDI 573
IGF-1R Others

Dusigitumab (MEDI 573) is a human IgG2λ monoclonal antibody that specifically targets IGF2 and IGF1 .

HY-P99197

Figitumumab CP-751871	IGF-1R	Cancer
Figitumumab (CP-751871) is a potent and fully human monoclonal anti–insulin-like growth factor 1 receptor (IGF1R) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC₅₀ of 1.8 nM .

HY-P99218

Robatumumab Sch 717454; 19D12	IGF-1R	Cancer
Robatumumab (Sch 717454) is an anti-human *IGF-1R* (insulin-like growth factor receptor-1) antibody. Robatumumab shows anti-tumor activity and anti-proliferative activity to cancer cells. Robatumumab can be used in osteosarcoma and Ewing sarcoma research .

HY-P99189

Cixutumumab IMC-A12; NSC742460	Inhibitory Antibodies	Cancer
Cixutumumab (IMC-A12) is a human anti-IGF-1R monoclonal antibody with high affinity that inhibits ligand-dependent receptor activation and downstream signaling. Cixutumumab also mediates the internalization and degradation of *IGF-IR*. Cixutumumab shows broad-spectrum anti-tumour activity and can be used in studies of cancers such as lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer .

HY-P990084

Veligrotug

IGF-1R Cancer

Veligrotug is an IgG1-kappa, anti-IGF1R (insulin-like growth factor 1 receptor, CD221) chimeric monoclonal antibody .

HY-P99712

Lonigutamab hz208F2-4	IGF-1R ADC Antibody	Cancer
Lonigutamab (hz208F2-4) is a humanized anti-IGF-1R monoclonal antibody that can be used for the synthesis of antibody–agent conjugates (ADC) .

Species:	Human (33) Rhesus Macaque (2) Mouse (15) Rat (1) Cynomolgus (2) Pig (1)
Tag:	His (37) T7 (1) SUMO (1) Tag Free (13) Avi (7) GST (4) Fc (3)
Source:	HEK293 (27) P. pastoris (4) Sf9 insect cells (2) E. coli (22)

Cat. No.	Compare	Product Name	Species	Source

HY-P700185AF

	*Animal-Free IGF-II Protein, Mouse (His)* AL033362; IGF; IGF-; IGF-2; M; M6; M6pr; Mpr; Peg; Peg2	Mouse	E. coli
	IGF-II Protein plays a crucial role in glucose-mediated insulin secretion, acting as a physiological amplifier alongside insulin. Additionally, it exhibits osteogenic properties by enhancing osteoblast mitogenic activity through the phosphoactivation of MAPK1 and MAPK3. This dual functionality underscores the protein's importance in glucose homeostasis and bone metabolism, suggesting therapeutic relevance for insulin secretion and bone health contexts. Animal-Free IGF-II Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIGF-II protein, expressed by E. coli, with N-His labeled tag. The total length of Animal-Free IGF-II Protein, Mouse (His) is 67 a.a., with molecular weight of ~8.20 kDa.

HY-P7070

IGF-I/IGF-1 Protein, Mouse

4 Publications Verification

rMuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I
Mouse E. coli

IGF-I/IGF-1 Protein, Mouse is a mitogenic cytokine.

HY-P7018

	IGF-I/IGF-1 Protein, Human (70a.a) Maximum Cited Publications 9 Publications Verification rHuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I	Human	E. coli
	IGF-I/IGF-1 Protein, Human (70a.a) is a mitogenic cytokine, binds to IGF type 1 receptor, and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone; IGF-I/IGF-1 Protein also mediates neuroprotective mechanism.

HY-P7019

	IGF2 Protein, Human 2 Publications Verification rHuIGF-2; Somatamedin A; IGF-II	Human	E. coli
	IGF2 Protein, Human is a mitogenic cytokine, binds to IGF type 1 receptor, and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone.

HY-P70698AF

	*Animal-Free IGF-I/IGF-1 Protein, Mouse (His)* rMuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I	Mouse	E. coli
	The IGF-I/IGF-1 protein is structurally similar to insulin and has potent growth-promoting activity. As a physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts, exceeding the efficacy of insulin at lower concentrations. Animal-Free IGF-I/IGF-1 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIGF-I/IGF-1 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IGF-I/IGF-1 Protein, Mouse (His) is 70 a.a., with molecular weight of ~8.61 kDa.

HY-P7203

	IGF-I/IGF-1 Protein, Rat 1 Publications Verification rRtIGF-I; Somatomedin C; IGF1; Mechano growth factor	Rat	E. coli
	IGF-I/IGF-1 Protein, Rat has somatomedin activity and ability to potently promote neuronal survival.

HY-P700093AF

	*Animal-Free IGF-I/IGF-1 Protein, Human (His)* 1 Publications Verification Somatamedin C; IGF-IA; Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1	Human	E. coli
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. Animal-Free IGF-I/IGF-1 Protein, Human (His) is the recombinant human-derived animal-FreeIGF-I/IGF-1 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IGF-I/IGF-1 Protein, Human (His) is 70 a.a., with molecular weight of ~8.59 kDa.

HY-P73906

	IGF2 Protein, Human (P.pastoris) Insulin-like growth factor II; IGF-II; Preptin; IGF2; PP1446	Human	P. pastoris
	The IGF2 protein is an important member of the insulin-like growth factor family and plays an important role in mammalian growth, fetoplacental development, and adult glucose metabolism. Regulated by placental prolactin, affecting tissue differentiation. IGF2 Protein, Human (P.pastoris) is the recombinant human-derived IGF2 protein, expressed by P. pastoris , with tag free. The total length of IGF2 Protein, Human (P.pastoris) is 67 a.a., with molecular weight of ~7.5 kDa.

HY-P78458

	IGF-I R Protein, Human (HEK293, His-Avi) CD221; IGF1R; IGF-1R; IGF-I R; IGF-I receptor; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216	Human	HEK293
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His-Avi) is the recombinant human-derived IGF-I R protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of IGF-I R Protein, Human (HEK293, His-Avi) is 902 a.a., with molecular weight of 110-130 kDa (alpha subunit) & 52-55 kDa (beta subunit), respectively.

HY-P70787

	IGF-I/IGF-1 Protein, Human (67a.a) Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1	Human	E. coli
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (67a.a) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by E. coli , with tag free. The total length of IGF-I/IGF-1 Protein, Human (67a.a) is 67 a.a., with molecular weight of ~9.0 kDa.

HY-P700094AF

	*Animal-Free IGF2 Protein, Human (His)* Somatamedin A; IGF-II	Human	E. coli
	The IGF2 protein is an important member of the insulin-like growth factor family and plays an important role in mammalian growth, fetoplacental development, and adult glucose metabolism. Regulated by placental prolactin, affecting tissue differentiation. Animal-Free IGF2 Protein, Human (His) is the recombinant human-derived animal-FreeIGF2 protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free IGF2 Protein, Human (His) is 67 a.a., with molecular weight of ~8.28 kDa.

HY-P78142

	IGF-I R Protein, Human (Biotinylated, HEK293, His-Avi) CD221; IGF1R; IGF-1R; IGF-I R; IGF-I receptor; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216	Human	HEK293
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of IGF-I R Protein, Human (Biotinylated, HEK293, His-Avi) is 902 a.a., with molecular weight of 110-120 kDa (alpha subunit) & 52-55 kDa (beta subunit), respectively.

HY-P70698

	IGF-I/IGF-1 Protein, Mouse (His) IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I; Somatomedin C; somatomedin-C	Mouse	E. coli
	IGF-I/IGF-1 Protein, Mouse (His) is a mitogenic cytokine, binds to IGF type 1 receptor, and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone. IGF1 also mediates neuroprotective mechanism.

HY-P70788

	IGF-I/IGF-1 Protein, Human (G49-A118) 5 Publications Verification Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1	Human	E. coli
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (G49-A118) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by E. coli , with tag free. The total length of IGF-I/IGF-1 Protein, Human (G49-A118) is 70 a.a., with molecular weight of ~9.0 kDa.

HY-P700478

	IGF-I/IGF-1 Protein, Human (P. pastoris, N-His) 1 Publications Verification Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1	Human	P. pastoris
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (P. pastoris, N-His) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of IGF-I/IGF-1 Protein, Human (P. pastoris, N-His) is 70 a.a., with molecular weight of 9.7 kDa.

HY-P70698A

	IGF-I/IGF-1 Protein, Mouse (N-His) IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I; Somatomedin C; somatomedin-C	Mouse	E. coli
	The IGF-I/IGF-1 protein is structurally similar to insulin and has potent growth-promoting activity. As a physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts, exceeding the efficacy of insulin at lower concentrations. IGF-I/IGF-1 Protein, Mouse (N-His) is the recombinant mouse-derived IGF-I/IGF-1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IGF-I/IGF-1 Protein, Mouse (N-His) is 70 a.a., with molecular weight of ~10 kDa.

HY-P74843

	IGF-I/IGF-1 Protein, Mouse (P.pastoris) Insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1	Mouse	P. pastoris
	IGF-I/IGF-1 Protein, part of the insulin family, is highlighted. IGF-I/IGF-1 Protein, Mouse (P.pastoris) is the recombinant mouse-derived IGF-I/IGF-1 protein, expressed by P. pastoris, with tag free. The total length of IGF-I/IGF-1 Protein, Mouse (P.pastoris) is 70 a.a., with molecular weight of ~7.7 kDa.

HY-P73136

	IGF-I/IGF-1 Protein, Human (HEK293, hFc) Insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1	Human	HEK293
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (HEK293, hFc) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of IGF-I/IGF-1 Protein, Human (HEK293, hFc) is 70 a.a., with molecular weight of 35-40 kDa.

HY-P72256

	IGF-I R Protein, Human (His) CD221; CD221 antigen ; IGF 1 receptor; IGF 1R; IGF I receptor; IGF-I receptor; IGF1r; IGF1R_HUMAN; IGFIR; IGFIRC; IGFR; Insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; MGC142170; MGC142172; MGC18216; Soluble IGF1R variant 1; Soluble IGF1R variant 2	Human	E. coli
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (His) is the recombinant human-derived IGF-I R protein, expressed by E. coli , with N-6*His labeled tag. The total length of IGF-I R Protein, Human (His) is 169 a.a., with molecular weight of ~23.4 kDa.

HY-P72606

	IGF-I R Protein, Human (HEK293, His) Insulin-like growth factor 1 receptor; IGF-I receptor; IGF1R; CD221	Human	HEK293
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IGF-I R Protein, Human (HEK293, His) is 902 a.a., with molecular weight of 100-130 & 54 kDa, respectively.

HY-P701241

	IGF-I Protein, Salmon IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I; Somatomedin C; somatomedin-C	Others	E. coli
	IGF-I protein is similar to insulin and exerts effective growth-promoting activity as a ligand of IGF1R. Binding to the α subunit of IGF1R activates intrinsic tyrosine kinase, triggering autophosphorylation of the β subunit. IGF-I Protein, Salmon is the recombinant IGF-I protein, expressed by E. coli , with tag free. The total length of IGF-I Protein, Salmon is 70 a.a., with molecular weight of ~8 kDa.

HY-P73137

	IGF-I R Protein, Human (sf9, His-GST) Insulin-like growth factor 1 receptor; IGF-I receptor; CD221; IGF1R	Human	Sf9 insect cells
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (sf9, His-GST) is the recombinant human-derived IGF-I R protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of IGF-I R Protein, Human (sf9, His-GST) is 414 a.a., with molecular weight of ~74.6 kDa.

HY-P74442

	IGF-I R Protein, Human (HEK293, His, solution) Insulin-like growth factor 1 receptor; IGF-I receptor; CD221; IGF1R	Human	HEK293
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His, solution) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-His labeled tag. The total length of IGF-I R Protein, Human (HEK293, His, solution) is 902 a.a., with molecular weight of ~150 kDa.

HY-P700870

	IGF2R Protein, Human (HEK293, His-Avi) CI-MPR; M6PR; MPR 300; IGF-II receptor; M6P/IGF2R; CD222; MPRI	Human	HEK293
	IGF2R Protein orchestrates cellular processes by transporting phosphorylated lysosomal enzymes from the Golgi complex to lysosomes. Lysosomal enzymes, with phosphomannosyl residues, bind to mannose-6-phosphate receptors in the Golgi, forming a complex transported to an acidic prelysosomal compartment. The low pH facilitates complex dissociation, and the receptor is recycled via interaction with the retromer. IGF2R also binds IGF2, positively regulates T-cell coactivation with DPP4, and engages with HA-I and HA-II plasma membrane adapters, showcasing its versatile molecular interactions in intracellular transport. IGF2R Protein, Human (HEK293, His-Avi) is the recombinant human-derived IGF2R protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of IGF2R Protein, Human (HEK293, His-Avi) is 1462 a.a., with molecular weight of 165-200 kDa.

HY-P700241AF

	*Animal-Free IGF-I Protein, Pig (His)* Insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1	Pig	E. coli
	The IGF-I protein is structurally similar to insulin and has excellent growth-promoting activity. As a potential physiological regulator, it affects [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Animal-Free IGF-I Protein, Pig (His) is the recombinant pig-derived animal-FreeIGF-I protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IGF-I Protein, Pig (His) is 70 a.a., with molecular weight of ~8.59 kDa.

HY-P700869

	IGF2R Protein, Human (Biotinylated, HEK293, His-Avi) CI-MPR; M6PR; MPR 300; IGF-II receptor; M6P/IGF2R; CD222; MPRI	Human	HEK293
	IGF2R Protein orchestrates cellular processes by transporting phosphorylated lysosomal enzymes from the Golgi complex to lysosomes. Lysosomal enzymes, with phosphomannosyl residues, bind to mannose-6-phosphate receptors in the Golgi, forming a complex transported to an acidic prelysosomal compartment. The low pH facilitates complex dissociation, and the receptor is recycled via interaction with the retromer. IGF2R also binds IGF2, positively regulates T-cell coactivation with DPP4, and engages with HA-I and HA-II plasma membrane adapters, showcasing its versatile molecular interactions in intracellular transport. IGF2R Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IGF2R protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of IGF2R Protein, Human (Biotinylated, HEK293, His-Avi) is 1462 a.a., with molecular weight of 165-200 kDa.

HY-P700871

	IGF2R Protein, Human (Domain 1-3, HEK293, His-Avi) CI-MPR; M6PR; MPR 300; IGF-II receptor; M6P/IGF2R; CD222; MPRI	Human	HEK293
	IGF2R Protein orchestrates cellular processes by transporting phosphorylated lysosomal enzymes from the Golgi complex to lysosomes. Lysosomal enzymes, with phosphomannosyl residues, bind to mannose-6-phosphate receptors in the Golgi, forming a complex transported to an acidic prelysosomal compartment. The low pH facilitates complex dissociation, and the receptor is recycled via interaction with the retromer. IGF2R also binds IGF2, positively regulates T-cell coactivation with DPP4, and engages with HA-I and HA-II plasma membrane adapters, showcasing its versatile molecular interactions in intracellular transport. IGF2R Protein, Human (Domain 1-3, HEK293, His-Avi) is the recombinant human-derived IGF2R protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of IGF2R Protein, Human (Domain 1-3, HEK293, His-Avi) is 422 a.a., with molecular weight of 55-65 kDa.

HY-P701061

	IGF2R Protein, Human (Domain 1-7, HEK293, His-Avi) CI-MPR; M6PR; MPR 300; IGF-II receptor; M6P/IGF2R; CD222; MPRI	Human	HEK293
	IGF2R proteins coordinate cellular processes by transporting phosphorylated lysosomal enzymes from the Golgi complex to lysosomes. Lysosomal enzymes with phosphomannosyl residues bind to mannose-6-phosphate receptors in the Golgi apparatus, form complexes, and transport to the acidic prelysosomal compartment. IGF2R Protein, Human (Domain 1-7, HEK293, His-Avi) is the recombinant human-derived IGF2R protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of IGF2R Protein, Human (Domain 1-7, HEK293, His-Avi) is 1033 a.a., with molecular weight of 120-160 kDa.

HY-P78586

	IGF-I R Protein, Cynomolgus (HEK293, His) IGF1R; IGFR; JTK13; CD221; MGC142170; MGC142172; MGC18216	Cynomolgus	HEK293
	The IGF-I R protein is a receptor tyrosine kinase that mediates the effects of insulin-like growth factor 1 (IGF1) and has high affinity for IGF1. Upon ligand binding, IGF1R is activated, leading to autophosphorylation and tyrosine phosphorylation of substrates, including IRS1/2, Shc, and 14-3-3 proteins. IGF-I R Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IGF-I R protein, expressed by HEK293 , with C-His labeled tag. The total length of IGF-I R Protein, Cynomolgus (HEK293, His) is 878 a.a., with molecular weight (glycosylation form) of 48-58 kDa (β subunit) & 100-115 kDa (α subunit) & 130-150 kDa, respectively.

HY-P78723

	IGF-I R Protein, Mouse (HEK293, His) IGF1R; IGFR; JTK13; CD221; MGC142170; MGC142172; MGC18216	Mouse	HEK293
	The IGF-I R protein, a receptor tyrosine kinase, mediates insulin-like growth factor 1 (IGF1) actions, with high affinity for IGF1. Upon ligand binding, IGF1R activates, leading to autophosphorylation and tyrosine phosphorylation of substrates, including IRS1/2, Shc, and 14-3-3 proteins. Phosphorylation initiates PI3K-AKT/PKB and Ras-MAPK pathways, regulating proliferation and apoptosis. IGF1R signals through JAK/STAT, activating STAT3, contributing to its transforming activity. It also activates JNK and inhibits JNK activation, forming a hybrid receptor with INSR to bind IGF1. IGF-I R Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGF-I R protein, expressed by HEK293, with C-His labeled tag. The total length of IGF-I R Protein, Mouse (HEK293, His) is 906 a.a., with molecular weight of 110-140 & 50-65 kDa, respectively.

HY-P70950

	IGF2BP2 Protein, Human (T7-His) Insulin-Like Growth Factor 2 mRNA-Binding Protein 2; IGF2 mRNA-Binding Protein 2; IMP-2; Hepatocellular Carcinoma Autoantigen p62; IGF-II mRNA-Binding Protein 2; VICKZ Family Member 2; IGF2BP2; IMP2; VICKZ2	Human	E. coli
	The IGF2BP2 protein is an RNA-binding factor that coordinates the recruitment of target transcripts into cytoplasmic mRNP, promoting mRNA transport and transient storage. It regulates the contact of target transcripts with the translation machinery and protects them from microRNA-mediated degradation. IGF2BP2 Protein, Human (T7-His) is the recombinant human-derived IGF2BP2 protein, expressed by E. coli , with N-T7, C-6*His labeled tag. The total length of IGF2BP2 Protein, Human (T7-His) is 220 a.a., with molecular weight of ~43.0 kDa.

HY-P74850

	IGF2BP2 Protein, Human (sf9, His-GST) Insulin-like growth factor 2 mRNA-binding protein 2; IMP-2; IGF2BP2; VICKZ2	Human	Sf9 insect cells
	The IGF2BP2 protein is an RNA-binding factor that coordinates the recruitment of target transcripts into cytoplasmic mRNP, promoting mRNA transport and transient storage. It regulates the contact of target transcripts with the translation machinery and protects them from microRNA-mediated degradation. IGF2BP2 Protein, Human (sf9, His-GST) is the recombinant human-derived IGF2BP2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of IGF2BP2 Protein, Human (sf9, His-GST) is 599 a.a., with molecular weight of ~90 kDa.

HY-P7020

	IGFBP-3 Protein, Human rHuIGF-BP3; IBP-3; IGF-binding protein 3; IGFBP-3	Human	E. coli
	IGFBP-3 Protein, Human belongs to insulin-like growth factor-binding protein, prolongs the half-life of the insulin-like growth factors (IGFs), inhibits interaction of IGFs with their cell surface receptors, and functions in cancer reduction.

HY-P700475

	IGF2 Protein, Human (GST) insulin-like growth factor 2 (somatomedin A); INSIGF; pp9974; C11orf43; FLJ22066; FLJ44734; IGF2; insulin-like growth factor 2; IGF-II; somatomedin A; somatomedin-A; insulin-like growth factor II; insulin-like growth factor type 2; putative insulin-like growth factor II associated protein; chromosome 11 open reading frame 43; OTTHUMP00000011157; OTTHUMP00000011018	Human	E. coli
	The IGF2 protein is an important member of the insulin-like growth factor family and plays an important role in mammalian growth, fetoplacental development, and adult glucose metabolism. Regulated by placental prolactin, affecting tissue differentiation. IGF2 Protein, Human (GST) is the recombinant human-derived IGF2 protein, expressed by E. coli , with N-GST labeled tag. The total length of IGF2 Protein, Human (GST) is 151 a.a., with molecular weight of 44.1 kDa.

HY-P73138

	IGFBP-3 Protein, Human (HEK293, His) Insulin-like growth factor-binding protein 3; IGF-BP3; IBP-3; IGFBP-3	Human	HEK293
	IGFBP-3 protein is a part of IGFBP that significantly prolongs IGF half-life and modulates growth effects in cell culture. It inhibits or stimulates IGF-induced cellular responses by changing the kinetics of interaction with cell surface receptors. IGFBP-3 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-3 protein, expressed by HEK293 , with N-His labeled tag. The total length of IGFBP-3 Protein, Human (HEK293, His) is 264 a.a., with molecular weight of 40-45 kDa.

HY-P74846

	IGFBP-2 Protein, Mouse (HEK293, His) IBP-2; Insulin-like growth factor binding protein 2; IGFBP2; IGF-BP53	Mouse	HEK293
	IGFBP-2 protein, a member of the IGF-binding protein family, inhibits IGF-mediated growth and developmental rates. It can extend the half-life of IGF and exhibit dual functions by inhibiting or stimulating the growth-promoting effect of IGF in cell culture. IGFBP-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-2 Protein, Mouse (HEK293, His) is 271 a.a., with molecular weight of ~32-40 kDa.

HY-P74847

	IGFBP-2 Protein, Mouse (HEK293, Fc) IBP-2; Insulin-like growth factor binding protein 2; IGFBP2; IGF-BP53	Mouse	HEK293
	IGFBP-2 protein, a member of the IGF-binding protein family, inhibits IGF-mediated growth and developmental rates. It can extend the half-life of IGF and exhibit dual functions by inhibiting or stimulating the growth-promoting effect of IGF in cell culture. IGFBP-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IGFBP-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IGFBP-2 Protein, Mouse (HEK293, Fc) is 305 a.a., with molecular weight of ~56.6 kDa.

HY-P70357

	IGFBP-6 Protein, Mouse (HEK293, His) rMuInsulin-like growth factor-binding protein 6/IGFBP-6, His; Insulin-like growth factor-binding protein 6; IBP-6; IGF-binding protein 6; IGFBP-6; IGFbp6; IBP6; IGF binding protein 6; insulin-like growth factor-binding protein 6	Mouse	HEK293
	IGFBP-6 protein can extend the half-life of IGF and regulate its effects. It can inhibit or stimulate the growth-promoting effects of IGF. IGFBP-6 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-6 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IGFBP-6 Protein, Mouse (HEK293, His) is 213 a.a., with molecular weight of ~28.0 kDa.

HY-P77393

	IGFBP-4 Protein, Cynomolgus (HEK293, His) Insulin-like growth factor-binding protein 4; IGF-BP-4; IBP-4; IGFBP-4; BP4	Cynomolgus	HEK293
	IGFBP-4 protein lacks essential conserved residue(s) for propagating feature annotation. IGFBP-4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IGFBP-4 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-4 Protein, Cynomolgus (HEK293, His) is 235 a.a., with molecular weight of 33-36 kDa.

HY-P77396

	IGFLR1 Protein, Human (HEK293, Fc) IGF-like family receptor 1; Transmembrane protein 149; TMEM149; U2AF1L4	Human	HEK293
	IGFLR1 protein, a probable cell membrane receptor, exhibits specific affinity for IGF-like family proteins IGFL1 and IGFL3, with higher binding affinity compared to others. This selective interaction profile suggests a key role for IGFLR1 in mediating cellular responses to these ligands, emphasizing its significance in the intricate network of cellular signaling pathways. IGFLR1 Protein, Human (HEK293, Fc) is the recombinant human-derived IGFLR1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IGFLR1 Protein, Human (HEK293, Fc) is 159 a.a., with molecular weight of ~58.9 & 47.6 kDa, respectively.

HY-P78713

	CCN2/CTGF Protein, Rhesus macaque (HEK293, His) CCN2; NOV2; HCS24; IGFBP8; IBP-8; IGFBP-8; IGF-binding protein 8	Rhesus Macaque	HEK293
	CCN2 is a mitogen secreted by vascular endothelial cells and a mechanosensor of mesenchymal cell differentiation that secretes stromal cell proteins. CCN2 can sense appropriate mechanical stress and downregulate its expression accordingly. CCN2 is a classic epithelial-to-mesenchymal transition (EMT) and fibrosis marker. CCN2/CTGF Protein, Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CCN2/CTGF protein, expressed by HEK293, with C-His labeled tag. The total length of CCN2/CTGF Protein, Rhesus macaque (HEK293, His) is 323 a.a., with molecular weight of 39-45 kDa.

HY-P700256

	IGFBP-1 Protein, Mouse (SUMO, His) Insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12	Mouse	E. coli
	The IGFBP-1 protein is an insulin-like growth factor binding protein that extends the half-life of IGF and modulates its growth-promoting effects in cell cultures, thereby inhibiting or stimulating these responses. Crucially, it alters the interaction between IGF and its cell surface receptors and promotes cell migration. IGFBP-1 Protein, Mouse (SUMO, His) is the recombinant mouse-derived IGFBP-1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of IGFBP-1 Protein, Mouse (SUMO, His) is 247 a.a., with molecular weight of ~43 kDa.

HY-P72608

	IGFBP-1 Protein, Human (HEK293, His) Insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12	Human	HEK293
	IGFBP-1 protein extends the half-life of IGFs and modulates their activity. It can inhibit or stimulate IGFs' growth-promoting effects, altering their interaction with receptors and fine-tuning signaling pathways. IGFBP-1 promotes cell migration and binds to both IGF1 and IGF2, highlighting its versatile role in modulating IGF signaling pathways. IGFBP-1 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IGFBP-1 Protein, Human (HEK293, His) is 234 a.a., with molecular weight of 30-35 kDa.

HY-P76409

	IGFBP-2 Protein, Rhesus Macaque (HEK293, His) Insulin-like growth factor 2 mRNA-binding protein 2; IMP-2; IGF2BP2; VICKZ2	Rhesus Macaque	HEK293
	IGFBP‐2 is a member of a family of six insulin‐like growth factor (IGF) binding proteins. IGFBP-2 is the second most abundant IGFBP in the circulation and binds IGF-II with higher affinity than IGF-I. IGFBP-2 has been implicated in the regulation of IGF activity in most tissues and organs. IGFBP-2 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived IGFBP-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-2 Protein, Rhesus Macaque (HEK293, His) is 289 a.a., with molecular weight of ~33 KDa.

HY-P72607

	IGFBP-4 Protein, Human (237a.a, HEK293, His) Insulin-Like Growth Factor-Binding Protein 4; IBP-4; IGF-Binding Protein 4; IGFBP-4; IBP4	Human	HEK293
	IGFBP-4 protein is an important IGFBP member that prolongs the half-life of insulin-like growth factor (IGF) and modulates its effects on cell cultures by altering the kinetics of interaction with cell surface receptors. It can inhibit or stimulate IGF-induced growth responses, showing specificity for IGF2 but not IGF1. IGFBP-4 Protein, Human (237a.a, HEK293, His) is the recombinant human-derived IGFBP-4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IGFBP-4 Protein, Human (237a.a, HEK293, His) is 237 a.a., with molecular weight of 30-35 kDa.

HY-P700486

	IGFBP-1 Protein, Mouse (P. pastoris, N-His) IGFbp1; IGFbp-1; Insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1	Mouse	P. pastoris
	The IGFBP-1 protein is an insulin-like growth factor binding protein that extends the half-life of IGF and modulates its growth-promoting effects in cell cultures, thereby inhibiting or stimulating these responses. Crucially, it alters the interaction between IGF and its cell surface receptors and promotes cell migration. IGFBP-1 Protein, Mouse (P. pastoris, N-His) is the recombinant mouse-derived IGFBP-1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of IGFBP-1 Protein, Mouse (P. pastoris, N-His) is 247 a.a., with molecular weight of 44 kDa.

HY-P72378

	IGFBP-5 Protein, Human (Biotinylated, HEK293, His-Avi) Insulin-Like Growth Factor-Binding Protein 5; IBP-5; IGF-Binding Protein 5; IGFBP-5; IGFBP5; IBP5	Human	HEK293
	The IGFBP-5 protein regulates insulin-like growth factor (IGF) and extends its lifespan. It can inhibit or stimulate the growth-promoting effect of IGF, showing its dual regulatory function. IGFBP-5 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IGFBP-5 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of IGFBP-5 Protein, Human (Biotinylated, HEK293, His-Avi) is 252 a.a., with molecular weight of 32-45 kDa.

HY-P70726

	IGFBP-7 Protein, Human (HEK293, His) Insulin-like growth factor-binding protein 7; IGFBP7; IGF-binding protein 7; IGFBP-rP1; MAC25 protein; Tumor-derived adhesion factor; TAF	Human	HEK293
	IGFBP-7 Protein, with relatively low IGF-I and IGF-II affinity, stimulates prostacyclin (PGI2) production and enhances cell adhesion. The significance of its interaction with VPS24/CHMP3 remains uncertain and warrants further investigation. IGFBP-7 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IGFBP-7 Protein, Human (HEK293, His) is 256 a.a., with molecular weight of 30-35 kDa.

HY-P70858

	IGFBP-7 Protein, Mouse (HEK293, His) Insulin-like growth factor-binding protein 7; IGFBP7; IGF-binding protein 7; IGFBP-rP1; MAC25 protein; Tumor-derived adhesion factor; TAF	Mouse	HEK293
	IGFBP-7 Protein, with modest affinity, binds to IGF-I and IGF-II, and notably stimulates prostacyclin (PGI2) production. Beyond its interaction with insulin-like growth factors, IGFBP-7 contributes to cell adhesion, indicating its role in cellular processes associated with adhesion and potential influence on cell-matrix interactions. These functionalities highlight IGFBP-7's diverse roles in modulating growth factor signaling and cellular responses. IGFBP-7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-7 protein, expressed by HEK293, with C-His labeled tag. The total length of IGFBP-7 Protein, Mouse (HEK293, His) is 256 a.a., with molecular weight of 32-38 kDa.

HY-P70408

	IGFBP-5 Protein, Mouse (HEK293, His) rMuInsulin-like growth factor-binding protein 5/IGFBP5, His; BP-5; IGFBP-5; IGF-binding protein 5; Insulin-like growth factor-binding protein 5;	Mouse	HEK293
	IGFBP-5 protein is a member of the IGFBP family that significantly prolongs the half-life of IGF and modulates its growth-promoting effects in cell culture. The multifunctional IGFBP-5 can inhibit or stimulate cellular responses to IGF by altering the kinetics of interaction with IGF receptors. IGFBP-5 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-5 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IGFBP-5 Protein, Mouse (HEK293, His) is 252 a.a., with molecular weight of ~38.0 kDa.

Cat. No.	Product Name	Application	Reactivity

HY-P83447

IGF2 Antibody (YA3192)

C11orf43; IGF 2; IGF II; IGF2; INSIGF; Somatomedin A
WB, ICC/IF Human

HY-P81112

IGF 1 Antibody IBP1; IGF 1; IGF I; IGF-1; IGF IA; IGF IB; IGF1; IGFI; IGFIA; Insulin like growth factor 1 (somatomedin C); Full=Insulin-like growth factor I; Insulin Like Growth Factor 1; Insulin like growth factor IA; Insulin like growth factor IB; Mechano growth factor; MGF; Mechano growth factor; MGF; Somatomedia C; Somatomedin C; IGF1_HUMAN. IGF-I;	WB; ELISA; IP; IHC-P; IHC-F; IF	Human, Mouse, Rat, Dog(predicted: Pig, Cow, Rabbit, Sheep)
IGF 1 Antibody is an unconjugated, approximately 7.7/21 kDa, rabbit-derived, anti-IGF 1 polyclonal antibody. IGF 1 Antibody can be used for: WB, ELISA, IP, IHC-P, IHC-F, IF expriments in human, mouse, rat, dog, and predicted: pig, cow, rabbit, sheep background without labeling.

HY-P80717

IGF1 Receptor Antibody IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221	WB, IHC-P	Human
IGF1 Receptor Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 155 kDa, targeting to IGF1 Receptor. It can be used for WB,IHC-P assays with tag free, in the background of Human.

HY-P80825

*Phospho-IGF1 Receptor (Tyr1166) Antibody* IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221	WB, IP	Human, Mouse, Rat
Phospho-IGF1 Receptor (Tyr1166) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 155 kDa, targeting to Phospho-IGF1 Receptor (Tyr1166). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P81754

IGF2R Antibody (YA1499) IGF2R; MPRI; Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2R; CD222	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat

HY-P82288

IGF2BP2 Antibody (YA2033) IGF2BP2; IMP2; VICKZ2; Insulin-like growth factor 2 mRNA-binding protein 2; IGF2 mRNA-binding protein 2; IMP-2; Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; VICKZ family member 2	WB, IHC-P, ICC/IF	Human, Mouse, Rat

HY-P80724

IMP3 Antibody Cancer/testis antigen 98; CT98; DKFZp686F1078; hKOC; IF2B3_HUMAN; IGF II mRNA binding protein 3; IGF-II mRNA-binding protein 3; IGF2 mRNA binding protein 3; IGF2 mRNA-binding protein 3; IGF2BP3; IMP 3; IMP-3; Insulin like growth factor 2 mRNA binding prot	WB, ICC/IF, IP, FC	Human, Mouse, Rat
IMP3 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 64 kDa, targeting to IMP3. It can be used for WB,ICC/IF,IP,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P81844

IGFBP2 Antibody (YA1589)

IGFBP2; BP2; IBP2; Insulin-like growth factor-binding protein 2; IBP-2; IGF-binding protein 2; IGFBP-2
WB, IHC-P Human
HY-P83326

IGF2BP1 Antibody (YA3071)

insulin-like growth factor 2 mRNA binding protein 1; IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1
WB, IHC-P, IP Human, Mouse
HY-P82665

IGFBP1 Antibody (YA2410)

IGFBP1; IBP1; Insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; Placental protein 12; PP12
WB Human, Mouse, Rat

HY-P83334

IGFBP7 Antibody (YA3079) IGFBP7; MAC25; PSF; Insulin-like growth factor-binding protein 7; IBP-7; IGF-binding protein 7; IGFBP-7; IGFBP-rP1; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor; TAF	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat

HY-P81103

CTGF Antibody CCN 2; CCN-2; CCN2; Connective Tissue Growth Factor; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse, Rat(predicted: Chicken, Dog, Pig, Cow)
CTGF Antibody is an unconjugated, approximately 36 kDa, rabbit-derived, anti-CTGF polyclonal antibody. CTGF Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, and predicted: chicken, dog, pig, cow background without labeling.

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